Prions are remarkable infectious agents associated with certain brain diseases. But they also occur in fungi, experiments with which now provide plausible answers to some critical questions about prion biology.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Prusiner, S. B. Science 216, 136–144 (1982).
King, C. -Y. & Diaz-Avalos, R. Nature 428, 319–323 (2004).
Tanaka, M., Chien, P., Naber, N., Cooke, R. & Weissman, J. S. Nature 428, 323–328 (2004).
Collinge, J. Annu. Rev. Neurosci. 24, 519–550 (2001).
Uptain, S. M. & Lindquist, S. L. Annu. Rev. Microbiol. 56, 703–741 (2002).
Sparrer, H. E., Santoso, A., Szoka, F. & Weissman, J. S. Science 289, 595–599 (2000).
Maddelein, M. L., Reis, S. D., Duvezin-Caubet, S., Coulary-Salin, B. & Saupe, S. J. Proc. Natl Acad. Sci. USA 99, 7402–7407 (2002).
Liebman, S. W. Proc. Natl Acad. Sci. USA 99, 9098–9100 (2002).
Bruce, M. E. Br. Med. Bull. 66, 99–108 (2003).
Uptain, S. M., Sawicki, G. J., Caughey, B. & Lindquist, S. EMBO J. 20, 6236–6245 (2001).
Tuite, M. F. & Cox, B. S. Nature Rev. Mol. Cell Biol. 4, 878–889 (2003).
Kryndushkin, D. S., Alexandrov, I. M., Ter-Avanesyan, M. D. & Kushnirov, V. V. J. Biol. Chem. 278, 49636–49643 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tuite, M. The strain of being a prion. Nature 428, 265–267 (2004). https://doi.org/10.1038/428265a
Issue Date:
DOI: https://doi.org/10.1038/428265a
This article is cited by
-
Spongiform encephalopathy, cannibalism and Neanderthals extinction
Human Evolution (2004)
