The Per2 gene is a core component of the circadian clock in mammals. It now seems that the mouse Per2 gene is also involved in suppressing tumours, through other genes that affect cell proliferation and death.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Fu, L., Pelicano, H., Liu, J., Huang, P. & Lee, C. C. Cell 111, 41–50 (2002).
Zheng, B. H. et al. Nature 400, 169–173 (1999).
Konopka, R. J. & Benzer, S. Proc. Natl Acad. Sci. USA 68, 2112–2116 (1971).
Allada, R., Emery, P., Takahashi, J. S. & Rosbash, M. Annu. Rev. Neurosci. 24, 1091–1119 (2001).
Zheng, B. H. et al. Cell 105, 683–694 (2001).
Akhtar, R. A. et al. Curr. Biol. 12, 540–550 (2002).
Panda, S. et al. Cell 109, 307–320 (2002).
Storch, K. F. et al. Nature 417, 78–83 (2002).
Ueda, H. R. et al. Nature 418, 534–539 (2002).
Balsalobre, A., Damiola, F. & Schibler, U. Cell 93, 929–937 (1998).
Johnson, C. H. & Golden, S. S. Annu. Rev. Microbiol. 53, 389–409 (1999).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rosbash, M., Takahashi, J. The cancer connection. Nature 420, 373–374 (2002). https://doi.org/10.1038/420373a
Issue Date:
DOI: https://doi.org/10.1038/420373a
This article is cited by
-
Introducing Therioepistemology: the study of how knowledge is gained from animal research
Lab Animal (2017)
-
Aging Lesions: Background Versus Phenotype
Current Pathobiology Reports (2015)
-
‘One medicine—one pathology': are veterinary and human pathology prepared?
Laboratory Investigation (2008)
-
Time- and exercise-dependent gene regulation in human skeletal muscle
Genome Biology (2003)
-
Timing the cell cycle
Nature Cell Biology (2003)