Many messenger RNAs are not functional until they are processed by a complex called the spliceosome. It seems increasingly likely that processing is catalysed by the RNA — and not the protein — parts of this complex.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Nilsen, T. W. in RNA Structure and Function (eds Simons, R. W. & Grunberg-Manago, M.) 279–307 (Cold Spring Harbor Laboratory Press, New York, 1998).
Valadkhan, S. & Manley, J. L. Nature 413, 701–707 (2001).
Madhani, H. D. & Guthrie, C. Genes Dev. 8, 1071–1086 (1994).
Sun, J. S. & Manley, J. L. Genes Dev. 9, 843–854 (1995).
Valadkhan, S. & Manley, J. L. RNA 6, 206–219 (2000).
Yu, Y.-T, Maroney, P. A. & Nilsen, T. W. Cell 75, 1049–1059 (1993).
Sontheimer, E. J., Sun, S. & Piccirilli, J. A. Nature 388, 801–805 (1997).
Yean, S.-L, Wuenschell, G., Termini, J. & Lin, R.-J Nature 408, 881–884 (2000).
Collins, C. A. & Guthrie, C. Nature Struct. Biol. 7, 850–854 (2000).
Nissen, P., Hansen, J., Ban, N., Moore, P. B. & Steitz, T. A. Science 289, 920–930 (2000).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Newman, A. RNA enzymes for RNA splicing. Nature 413, 695–696 (2001). https://doi.org/10.1038/35099665
Issue Date:
DOI: https://doi.org/10.1038/35099665