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Nature 406, 147-150 (13 July 2000) | doi:10.1038/35018000

Transcranial magnetic stimulation and the human brain

Mark Hallett

Transcranial magnetic stimulation (TMS) is rapidly developing as a powerful, non-invasive tool for studying the human brain. A pulsed magnetic field creates current flow in the brain and can temporarily excite or inhibit specific areas. TMS of motor cortex can produce a muscle twitch or block movement; TMS of occipital cortex can produce visual phosphenes or scotomas. TMS can also alter the functioning of the brain beyond the time of stimulation, offering potential for therapy.

  1. Human Motor Control Section, National Institute of Neurological Disorders and Stroke, NIH, Building 10, Room 5N226, 10 Center Dr. MSC 1428, Bethesda, Maryland 20892-1428 , USA

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