Nature Cell Biology
2, E93 - E96 (2000)
doi:10.1038/35014084
 -tubulin nucleation: template or protofilament?
Harold P. Erickson
Harold P. Erickson is in the Department of Cell Biology,
Duke University Medical Center, Durham, North Carolina
27710, USA.
h.erickson@cellbio.duke.edu
 -tubulin is known to nucleate microtubule assembly from  / -tubulin,
but the molecular mechanism by which this process occurs is the subject of
some controversy. Four recent papers have provided new structural and biochemical
constraints on the models proposed for nucleation. These have refined, but
not yet resolved, the debate.
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