Charles N. Cole is at the Department of Biochemistry,
Dartmouth Medical School, Hanover, New Hampshire
03755, USA
charles.n.cole@dartmouth.edu
To the growing list of factors required for the export of messenger RNA
from nucleus to cytoplasm can now be added Yra1. Yeast Yra1 and its metazoan
orthologues bind mRNAs and interact with multiple mRNA export factors.Transport
of proteins and small RNAs does not require Yra1 or any other proteins required
for mRNA export, suggesting that mRNA export may proceed by a different mechanism.
The finding that Yra1 has a role in mRNA export moves us one step closer to
identifying all the proteins required for this process.