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Nature Cell Biology  2, E55 - E58 (2000)
doi:10.1038/35008681

mRNA export: the long and winding road

Charles N. Cole

Charles N. Cole is at the Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
charles.n.cole@dartmouth.edu

To the growing list of factors required for the export of messenger RNA from nucleus to cytoplasm can now be added Yra1. Yeast Yra1 and its metazoan orthologues bind mRNAs and interact with multiple mRNA export factors.Transport of proteins and small RNAs does not require Yra1 or any other proteins required for mRNA export, suggesting that mRNA export may proceed by a different mechanism. The finding that Yra1 has a role in mRNA export moves us one step closer to identifying all the proteins required for this process.

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Nature Cell Biology
ISSN: 1465-7392
EISSN: 1476-4679
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