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Effects of sleep and arousal on the processing of visual information in the cat

Abstract

Single units in the cat lateral geniculate nucleus and primary visual cortex show changes in both spontaneous and visually evoked firing as a function of the state of wakefulness. On arousal spontaneous firing is smoother and often reduced, whereas evoked responses are usually enhanced; the result is an increase in the signal-to-noise ratio. Single- and double-label 2-deoxyglucose autoradiographs show further that slow-wave sleep differentially depresses visually evoked activity in the deeper layers of the visual cortex.

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References

  1. Hubel, D. H. J. Physiol., Lond. 150, 91–104 (1960).

    Article  CAS  Google Scholar 

  2. Singer, W. Physiol. Rev. 57, 386–420 (1977).

    Article  CAS  Google Scholar 

  3. Hubel, D. H. Am. J. Ophthal. 46, 110–122 (1958).

    Article  CAS  Google Scholar 

  4. Hubel, D. H. J. Physiol., Lond. 147, 226–238 (1959).

    Article  CAS  Google Scholar 

  5. Evarts, E. V. in The Nature of Sleep (eds Wolstenholme, G. E. W. & O'Connor, M.) 171–182 (Churchill, London, 1961).

    Google Scholar 

  6. Evarts, E. V., Bental, E., Bihari, B. & Huttenlocher, P. R. Science 135, 726–728 (1962).

    Article  ADS  CAS  Google Scholar 

  7. Coenen, A. U. L. & Vendrik, A. J. H. Expl Brain Res. 14, 227–242 (1972).

    Article  CAS  Google Scholar 

  8. Hubel, D. H. & Livingstone, M. S. Neurosci. Abstr. 10th a. Meet., Cincinnati, No. 113.3 (1980).

  9. Sokoloff, L. et al. J. Neurochem. 28, 897–916 (1979).

    Article  Google Scholar 

  10. Livingstone, M. S. & Hubel, D. H. Neurosci. Abstr. 10th a. Meet., Cincinnati, No. 113.4 (1980).

  11. Singer, W. & Dräger, U. C. Brain Res. 41, 214–220 (1972).

    Article  CAS  Google Scholar 

  12. Maffei, L. & Rizzolatti, C. T. Arch. ital. Biol. 103, 609–622 (1965).

    CAS  PubMed  Google Scholar 

  13. Sakakura, H. Jap. J. Physiol. 18, 23–42 (1968).

    Article  CAS  Google Scholar 

  14. Hubel, D. H. & Wiesel, T. N. J. Physiol., Lond. 155, 385–398 (1961).

    Article  CAS  Google Scholar 

  15. Kuffler, S. J. Neurophysiol. 16, 37–68 (1953).

    Article  CAS  Google Scholar 

  16. Barlow, H. B. J. Physiol., Lond. 119, 69–88 (1953).

    Article  CAS  Google Scholar 

  17. Cleland, B. G., Dubin, M. W. & Levick, W. R. Nature new Biol. 231, 191–192 (1971).

    Article  CAS  Google Scholar 

  18. Meulders, M. & Godfraind, J. M. Expl Brain Res. 9, 201–220 (1969).

    Article  CAS  Google Scholar 

  19. Singer, W., Tretter, F. & Cynader, M. Brain Res. 102, 71–90 (1976).

    Article  CAS  Google Scholar 

  20. Hubel, D. H. & Wiesel, T. N. J. Neurophysiol. 28, 229–289 (1965).

    Article  CAS  Google Scholar 

  21. Hubel, D. H. & Wiesel, T. N. J. Physiol., Lond. 160, 106–154 (1962).

    Article  CAS  Google Scholar 

  22. Hubel, D. H. & Wiesel, T. N. J. Physiol., Lond. 195, 215–243 (1968).

    Article  CAS  Google Scholar 

  23. Wurtz, R. H. J. Neurophysiol. 32, 727–742 (1969).

    Article  CAS  Google Scholar 

  24. Sherrington, C. S. Man on His Nature, 183–184 (Doubleday, New York, 1953).

    Google Scholar 

  25. Murata, K. & Kameda, K. Arch. ital. Biol. 101, 306–331 (1963).

    CAS  PubMed  Google Scholar 

  26. Akimoto, H., Saito, Y. & Nakamura, Y. Neurophysiologie und Psychophysik des visuellen Systems (eds Jung, R. & Kornhuber, H.) 363–374 (Springer, Berlin, 1961).

    Google Scholar 

  27. Evarts, E. V. J. Neurophysiol. 26, 229–248 (1963).

    Article  Google Scholar 

  28. Evarts, E. V. in Colloque International sur les Aspects Anatomo-fonctionnels de la Physiologie du Sommeil, 189–212 (Éditions du Centre National de la Recherche Scientifique, Paris, 1965).

    Google Scholar 

  29. Gross, C. G., Rocha-Miranda, C. E. & Bender, D. B. J. Neurophysiol. 35, 96–111 (1972).

    Article  CAS  Google Scholar 

  30. Gücer, G. Expl Brain Res. 34, 287–298 (1979).

    Article  Google Scholar 

  31. Mollica, A., Moruzzi, G. & Naquet, R. EEG J. 5, 571–584 (1953).

    CAS  Google Scholar 

  32. Machne, X., Calma, I. & Magoun, H. W. J. Neurophysiol. 18, 547–558 (1955).

    Article  CAS  Google Scholar 

  33. Strumwasser, F. Science 127, 469–470 (1958).

    Article  ADS  CAS  Google Scholar 

  34. Schlag, J. L'activité Spontanée des Cellules du Système Nerveux Central (Editions Arscia, Bruxelles, 1959).

    Google Scholar 

  35. Huttenlocher, P. R. J. Neurophysiol. 24, 451–568 (1961).

    Article  Google Scholar 

  36. Beniot, O. J. Physiol., Paris 56, 259–262 (1964).

    Google Scholar 

  37. Kasamatsu, T. Brain Res. 14, 506–509 (1969).

    Article  CAS  Google Scholar 

  38. Kasamatsu, T. Expl Neurol. 28, 450–470 (1970).

    Article  CAS  Google Scholar 

  39. Hobson, J. A., McCarley, R. W., Pivik, R. T. & Freedman, R. J. Neurophysiol. 37, 497–511 (1974).

    Article  CAS  Google Scholar 

  40. Chu, N.-S. & Bloom, F. E. Science 179, 908–910 (1973).

    Article  ADS  CAS  Google Scholar 

  41. McGinty, D. J., Harper, R. M. & Fairbanks, M. K. Serotonin and Behavior (eds Barchas, S. & Usdinin, E.) 267–279 (Academic, New York, 1973).

    Google Scholar 

  42. McGinty, D. J. & Harper, R. M. Brain Res. 101, 569–575 (1976).

    Article  CAS  Google Scholar 

  43. Foote, S. L., Aston-Jones, G. & Bloom, F. E. Proc. natn. Acad. Sci. U.S.A. 77, 3033–3037 (1980).

    Article  ADS  CAS  Google Scholar 

  44. Trulson, M. E. & Jacobs, B. L. Brain Res. 163, 135–150 (1979).

    Article  CAS  Google Scholar 

  45. Moore, R. Y. & Bloom, F. E. A. Rev. Neurosci. 2, 113–168 (1979).

    Article  CAS  Google Scholar 

  46. Moore, R. Y., Halaris, A. E. & Jones, B. E. J. comp. Neural. 180, 417–438 (1978).

    Article  CAS  Google Scholar 

  47. Wickelgren, B. G. & Sterling, P. J. Neurophysiol. 32, 16–32 (1969).

    Article  CAS  Google Scholar 

Download references

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Livingstone, M., Hubel, D. Effects of sleep and arousal on the processing of visual information in the cat. Nature 291, 554–561 (1981). https://doi.org/10.1038/291554a0

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