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Expression of a chicken chromosomal ovalbumin gene injected into frog oocyte nuclei

Nature volume 285, pages 628–634 (1980)Cite this article

Abstract

Ovalbumin is synthesized by Xenopus oocytes injected with a plasmid containing either the chicken chromosomal ovalbumin gene or a plasmid from which the 5′ region of the chromosomal gene has been deleted. However, oocytes injected with a plasmid containing full-length ovalbumin cDNA do not synthesize ovalbumin, despite the fact that at least as much stable, ovalbumin-specific RNA is transcribed from the cDNA as from the chromosomal gene.

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Author information

Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK

    M. P. Wickens & J. B. Gurdon

  2. Department of Cell Biology, Baylor College of Medicine, Houston, Texas, 77030

    S. Woo & B. W. O'Malley

Authors
  1. M. P. Wickens
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  2. S. Woo
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  3. B. W. O'Malley
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  4. J. B. Gurdon
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Wickens, M., Woo, S., O'Malley, B. et al. Expression of a chicken chromosomal ovalbumin gene injected into frog oocyte nuclei. Nature 285, 628–634 (1980). https://doi.org/10.1038/285628a0

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