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Protein conformation dictates prion strain

Abstract

A new conformation-based immunoassay provides a smart and sensitive way of differentiating between strains of prions, the infectious particles believed to cause spongiform encephalopathy (pages 1157–1165 ).

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Aguzzi, A. Protein conformation dictates prion strain. Nat Med 4, 1125–1126 (1998). https://doi.org/10.1038/2621

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