Nature 252, 495 - 497 (06 December 1974); doi:10.1038/252495a0

Transcriptional control of -foetoprotein synthesis in developing mouse liver

K. KOGA^*, D. W. O'KEEFE, T. IIO^† & T. TAMAOKI

University of Alberta Cancer Research Unit, (McEachern Laboratory) and Department of Biochemistry, Edmonton, Alberta, Canada
^*Present address: Agricultural Chemistry Institute, Kyushu University, Fukuoka, Japan.
^†On leave from Showa College of Pharmaceutical Sciences, Tokyo, Japan.

-FOETOPROTEIN (FP) is a dominant serum protein in many mammalian species during embryonic and early postnatal life. It is hardly detectable in the adult body but is often found in an elevated quantity in the serum of individuals with hepatocarcinomas and teratocarcinomas¹⁻⁵.

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