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Physical and Enzymatic Studies on Poly d(I–C).Poly d(I–C), an Unusual Double-helical DNA

Nature volume 228, pages 1166–1169 (1970)Cite this article

Abstract

X-ray diffraction and circular dichroism studies indicate that poly d(I–C).poly d(I–C) exists in a new polynucleotide configuration—an eight-fold helix, possibly left-handed.

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Author notes

  1. Y. MITSUI

    Present address: Department of Molecular Biophysics, Yale University, New Haven, Connecticut

  2. Y. MITSUI and R. LANGRIDGE: Department of Biochemical Sciences, Frick Chemical Laboratory, Princeton University, Princeton, New Jersey 08540

  3. BARBARA E. SHORTLE and CHARLES R. CANTOR: Department of Chemistry and Biological Sciences, Columbia University, New York 10027

  4. CHARLES R. CANTOR: Alfred P. Sloan fellow.

  5. BARBARA E. SHORTLE: Supported by a predoctoral fellowship from the US Public Health Service.

  6. ROBERT C. GRANT: NIH predoctoral trainee.

  7. MASAHIKO KODAMA: On leave of absence from the National Cancer Center, Tokyo, Japan.

  8. Y. MITSUI: On leave of absence from the University of Tokyo, Tokyo, Japan

Authors and Affiliations

  1. Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, 53706

    ROBERT C. GRANT, MASAHIKO KODAMA & ROBERT D. WELLS

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  1. Y. MITSUI
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  2. R. LANGRIDGE
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  4. CHARLES R. CANTOR
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  7. ROBERT D. WELLS
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MITSUI, Y., LANGRIDGE, R., SHORTLE, B. et al. Physical and Enzymatic Studies on Poly d(I–C).Poly d(I–C), an Unusual Double-helical DNA. Nature 228, 1166–1169 (1970). https://doi.org/10.1038/2281166a0

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  • DOI: https://doi.org/10.1038/2281166a0

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