Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Stimulus and Response during Early Pregnancy in the Mouse

Nature volume 221, pages 739–741 (1969)Cite this article

Abstract

In view of the necessity for synchrony between the development of the embryo and that of the uterus, control of implantation should depend on a complex network of events leading to a high degree of functional integration. In this article, Dr McLaren describes some of the changes that take place during early pregnancy in the mouse and considers some of the underlying mechanisms.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Tinbergen, N., The Study of Instinct (Clarendon Press, Oxford, 1951). Hinde, R. A., Animal Behaviour (McGraw-Hill Book Co., 1966).

    Google Scholar 

  2. Finn, C. A., and McLaren, A., J. Reprod. Fert., 13, 259 (1967).

    Article  CAS  Google Scholar 

  3. Reinius, S., Z. Zellforsch. Mikrosk. Anat., 77, 257 (1967).

    Article  CAS  Google Scholar 

  4. Potts, D. M., and Psychoyos, A., CR Hebd. Séanç. Acad. Sci., Paris, 264, 370 (1967).

    CAS  Google Scholar 

  5. Zhinkin, L. N., and Samoshkina, N. A., J. Embryol. Exp. Morph., 17, 593 (1967).

    CAS  PubMed  Google Scholar 

  6. Finn, C. A., and Martin, L., J. Endocrinol., 39, 593 (1967).

    Article  CAS  Google Scholar 

  7. Potts, D. M., Amer. J. Obstet. Gynec., 96, 1122 (1966); J. Anat., 103, 77 (1968).

    Article  CAS  Google Scholar 

  8. Enders, A. C., and Schlafke, S. J., Amer. J. Anat., 120, 185 (1967).

    Article  Google Scholar 

  9. Mayer, G., Nilsson, O., and Reinius, S., Z. Anat., 126, 43 (1967).

    Article  CAS  Google Scholar 

  10. Young, M. P., Whicher, J. T., and Potts, D. M., J. Embryol. Exp. Morph., 19, 341 (1968).

    CAS  PubMed  Google Scholar 

  11. Nilsson, O., Second Int. Semin. Repr. Physiol. Sex. Endocrinol., Brussels (in the press).

  12. Glenister, T. W., Fertil. Steril., Exc. Med. Fndn., ICS, 133, 385 (1966).

    Google Scholar 

  13. Potts, M., and Psychoyos, A., CR Hebd. Séanç. Acad. Sci., Paris, 264, 370 (1967).

    CAS  Google Scholar 

  14. Orsini, M. W., and McLaren, A., J. Reprod. Fert., 13, 485 (1967).

    Article  CAS  Google Scholar 

  15. McLaren, A., J. Reprod. Fert., 14, 159 (1967).

    Article  CAS  Google Scholar 

  16. McLaren, A., J. Endocrinol., 42, 453 (1968).

    Article  CAS  Google Scholar 

  17. Psychoyos, A., CR Hebd. Séanç. Acad. Sci., Paris, 252, 1515 (1961).

    CAS  Google Scholar 

  18. Krehbiel, R. H., Physiol. Zool., 10, 212 (1937).

    Article  Google Scholar 

  19. Wilson, I. B., Second Int. Semin. Repr. Physiol. Sex. Endocrinol., Brussels (in the press).

  20. Mulnard, J. G., Arch. Biol. (Liège), 78, 575 (1967).

    CAS  Google Scholar 

  21. Finn, C. A., and Lawn, A. M., J. Reprod. Fert., 15, 333 (1967).

    Article  Google Scholar 

  22. McLaren, A., Second Int. Semin. Repr. Physiol. Sex. Endocrinol., Brussels (in the press).

  23. Kraicer, P. F., and Shelesnyak, M. C., CR Hebd. Séanç. Acad. Sci., Paris, 248, 3213 (1959). Shelesnyak, M. C., Kraicer, P. F., and Zeilmaker, G. H., Acta Endocrinol., 42, 225 (1963). Shelesnyak, M. C., Marcus, G. J., Kraicer, P. F., and Lobel, B., Fertil. Steril. Exc. Med. Fndn., 363 (1967).

    CAS  Google Scholar 

  24. Emmens, C. W., Adv. Reprod. Physiol., 2, 213 (1967).

    Google Scholar 

  25. Segal, S. J., Davidson, O. W., and Wada, K., Proc. US Nat. Acad. Sci., 54, 782 (1965).

    Article  ADS  CAS  Google Scholar 

  26. McLaren, A., J. Reprod. Fert., 15, 313 (1968).

    Article  CAS  Google Scholar 

  27. McLaren, A., J. Reprod. Fert., (1969a, b) (in the press)

  28. Tarkowski, A. K., J. Embryol. Exp. Morph., 10, 476 (1962).

    CAS  PubMed  Google Scholar 

  29. Kirby, D. R. S., Second Int. Semin. Repr. Physiol. Sex. Endocrinol., Brussels (in the press).

  30. Kirby, D. R. S., Nature, 216, 1220 (1967).

    Article  ADS  CAS  Google Scholar 

  31. Finn, C. A., J. Endocrinol., 36, 239 (1966).

    Article  CAS  Google Scholar 

  32. Finn, C. A., and Keen, P. M., J. Embryol. Exp. Morph., 11, 673 (1963).

    CAS  PubMed  Google Scholar 

  33. Hetherington, C., J. Reprod. Fert., 17, 391 (1968).

    Article  CAS  Google Scholar 

  34. Hetherington, C., Nature, 219, 863 (1968).

    Article  ADS  CAS  Google Scholar 

  35. Brinster, R. L., Exp. Cell Res., 47, 271 (1967).

    Article  CAS  Google Scholar 

  36. Fridhandler, L., Exp. Cell Res., 22, 303 (1961).

    Article  CAS  Google Scholar 

  37. Böving, B. G., Physiological Mechanisms concerned with Conception (Pergamon Press, New York, 1963).

    Google Scholar 

  38. Smith, D. M., J. Endocrinol., 41, 17 (1968).

    Article  CAS  Google Scholar 

  39. Gwatkin, R. B. L., J. Cell Physiol., 68, 335 (1966).

    Article  Google Scholar 

  40. Krishnan, R. S., and Daniel, J. C., Science, 158, 490 (1967).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. ARC Unit of Animal Genetics, University of Edinburgh,

    ANNE MCLAREN

Authors
  1. ANNE MCLAREN
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

MCLAREN, A. Stimulus and Response during Early Pregnancy in the Mouse. Nature 221, 739–741 (1969). https://doi.org/10.1038/221739a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/221739a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing