Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

The Third Horseman takes wing

Nature Cell Biology volume 1, pages E123–E124 (1999)Cite this article

Abstract

The identification of a Drosophila homologue of the nematode cell-death protein CED-4 indicates a role for the apoptosome — a complex consisting of CED-4, CED-3 and CED-9 — in developmental cell deaths in Drosophila.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: A model for apoptosis in Drosophila.

References

  1. Zou, H., Henzel, W., Liu, X., Lutschg, A. & Wang, X. Cell 90, 405–413 (1997).

    Article  CAS  Google Scholar 

  2. Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M. & Horvitz, H. R. Cell 75, 641–652 (1993).

    Article  CAS  Google Scholar 

  3. Hengartner, M. O. & Horvitz, H. R. Cell 76, 665–676 (1994).

    Article  CAS  Google Scholar 

  4. Rodriguez, A. et al. Nature Cell Biol. 1, 272–279 (1999).

    Article  CAS  Google Scholar 

  5. Vaux, D. Cell 90, 389–390 (1997).

    Article  CAS  Google Scholar 

  6. Cryns, V. & Yuan, J. Genes Dev. 12, 1551–1570 (1998).

    Article  CAS  Google Scholar 

  7. Yoshida, H. et al. Cell 94, 739–750 (1998).

    Article  CAS  Google Scholar 

  8. Hu, Y., Ding, L., Spencer, D. & Nüñez, G. J. Biol. Chem. 273, 33489–33494 (1998).

    Article  CAS  Google Scholar 

  9. Srinivasula, S., Ahmad, M., Fernandes-Alnemri, T. & Alnemri, E. Mol. Cell 1, 949–957 (1998).

    Article  CAS  Google Scholar 

  10. Dorstyn, L., Colussi, P., Quinn, L., Richardson, H. & Kumar, S. Proc. Natl Acad. Sci. USA 96, 4307–4312 (1999).

    Article  CAS  Google Scholar 

  11. Li, P. et al. Cell 91, 479–489 (1997).

    Article  CAS  Google Scholar 

  12. Hakem, R. et al. Cell 94, 339–352 (1998).

    Article  CAS  Google Scholar 

  13. Kuida, K. et al. Cell 94, 325–337 (1998).

    Article  CAS  Google Scholar 

  14. McCall, K. & Steller, H. Trends Genet. 13, 222–226 (1997).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Kristin White is at the Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, 02129, Massachusetts, USA

    Kristin White

Authors
  1. Kristin White
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kristin White.

Rights and permissions

Reprints and permissions

About this article

Cite this article

White, K. The Third Horseman takes wing. Nat Cell Biol 1, E123–E124 (1999). https://doi.org/10.1038/12953

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/12953

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing