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Allogeneic stem cell transplantation for Evans syndrome

Bone Marrow Transplantation volume 28, pages 903–905 (2001)Cite this article

Abstract

Evans syndrome is a rare disorder characterized by combined autoimmune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA). Standard treatments consist of transfusions, corticosteroids, splenectomy, IVIG, anabolic steroids, vincristine, alkylating agents, or cyclosporine. In a patient with refractory disease, an allogeneic hematopoietic stem cell transplant (HSCT) resulted in complete clinical and serologic remission for more than 30 months. Allogeneic HSCT may be the only current curative therapy for Evans syndrome but may also be complicated by significant toxicities. Bone Marrow Transplantation (2001) 28, 903–905.

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  1. M Miranda: Retired

Authors and Affiliations

  1. Division of Immune Therapy and Autoimmune Diseases, Northwestern University Medical Center, Chicago, IL, USA

    Y Oyama, AE Traynor & RK Burt

  2. Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA

    EB Papadopoulos

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  1. Y Oyama
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  3. M Miranda
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  4. AE Traynor
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  5. RK Burt
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Oyama, Y., Papadopoulos, E., Miranda, M. et al. Allogeneic stem cell transplantation for Evans syndrome. Bone Marrow Transplant 28, 903–905 (2001). https://doi.org/10.1038/sj.bmt.1703237

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  • DOI: https://doi.org/10.1038/sj.bmt.1703237

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