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Evolutionary biology

Body plans and simple brains

Genes expressed in the vertebrate brain and spinal cord show up in the surface nerve net of a closely related group of invertebrates. Could this mean that brains started out on the body surface?

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Figure 1: Protostomes and deuterostomes.
Figure 2: Saccoglossus embryo showing expression patterns for two of the 22 genes examined by Lowe et al.1.

References

  1. Lowe, C. J. et al. Cell 113, 853–865 (2003).

    Article  CAS  Google Scholar 

  2. Holland, N. D. Nature Rev. Neurosci. doi:10.1038/nrn1175 (2003).

  3. Nieuwenhuys, R. Prog. Brain Res. 125, 49–126 (2000).

    Article  CAS  Google Scholar 

  4. Gee, H. Before the Backbone (Chapman & Hall, London, 1996).

    Google Scholar 

  5. Tagawa, K. et al. Evol. Dev. 3, 443–454 (2001).

    Article  CAS  Google Scholar 

  6. Gerhart, J. Proc. Natl Acad. Sci. USA 97, 1113–1122 (2000).

    Article  Google Scholar 

  7. Ruppert, E. E. Invert. Biol. 118, 202–212 (1999).

    Article  Google Scholar 

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Lacalli, T. Body plans and simple brains. Nature 424, 263–264 (2003). https://doi.org/10.1038/424263a

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