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Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

Nature volume 368, pages 208–214 (1994)Cite this article

Abstract

Drosophila limbs are subdivided into anterior and posterior compartments which derive from adjacent cell populations founded early in development. Evidence is now provided that posterior cells organize growth and cell patterning in both compartments by secreting hedgehog protein and that hedgehog protein acts indirectly by inducing neighbouring anterior cells to secrete decapentaplegic or wingless protein.

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Authors and Affiliations

  1. Zoologisches Institut, Universität Zürich, Winterthurerstrasse 190, 8057, Zürich, Switzerland

    Konrad Basler

  2. Howard Hughes Medical Institute, Columbia University College of Physicians and Surgeons, 701 West 168th Street, New York

    Gary Struhl

Authors
  1. Konrad Basler
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  2. Gary Struhl
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Basler, K., Struhl, G. Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein. Nature 368, 208–214 (1994). https://doi.org/10.1038/368208a0

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  • DOI: https://doi.org/10.1038/368208a0

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