Abstract.
We report the identification of nine DNA polymorphisms in PSPLA1 encoding phosphatidylserine-specific phospholipase A1. Because the gene product shares homology with triglyceride lipases, these polymorphisms may be useful in association studies with metabolic traits such as hypertriglyceridemia and related lipoprotein abnormalities, and will also provide tools for mapping studies of chromosome 3q13.13–13.2.
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Received: June 28, 2002 / Accepted: July 22, 2002
Acknowledgments Pearl Campbell provided outstanding technical assistance. Dr. Hegele holds a Canada Research Chair (Tier I) in Human Genetics and a Career Investigator award from the Heart and Stroke Foundation of Ontario. This work was supported by grants from Canadian Institutes for Health Research (MT13430), the Heart and Stroke Foundation of Ontario, the Canadian Genetic Diseases Network, and the Blackburn Group.
Correspondence to:R.A. Hegele
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Wang, J., Wen, XY., Stewart, A. et al. Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 (PSPLA1). J Hum Genet 47, 611–613 (2002). https://doi.org/10.1007/s100380200093
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DOI: https://doi.org/10.1007/s100380200093