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Hypertrophic cardiomyopathy: from gene defect to clinical disease

Man-Wei CHUNG, Tatiana TSOUTSMAN and Christopher SEMSARIAN

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Figure 1.

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Pathology of hypertrophic cardiomyopathy
A. Post-mortem examination of the heart from an individual ith HCM demonstrating massive asymmetric left ventricular hypertrophy, with associated reduction in left ventricular cavity size, compared to a normal heart. B. Histopathology of heart sections stained with Massons trichrome showing significant myofibre disarray and interstitial fibrosis in HCM.

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