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EDITOR'S CHOICE 2012
Cell Research is proud to present a collection of featured articles from 2012 from across the fields of basic molecular and cell biology research. These articles have been chosen by the Editor to illustrate some of the latest advances in topics such as stem cells, autophagy, cancer biology, miRNAs, trafficking, and immunity.
Reviews
Polarized sorting and trafficking in epithelial cells FREE
Xinwang Cao, Michal A Surma and Kai Simons
Cell Res 22: 793-805; advance online publication, April 24, 2012; doi:10.1038/cr.2012.64
Regulation of small RNA stability: methylation and beyond FREE
Lijuan Ji and Xuemei Chen
Cell Res 22: 624-636; advance online publication, March 13, 2012; doi:10.1038/cr.2012.36
Understanding cancer stem cell heterogeneity and plasticity FREE
Dean G Tang
Cell Res 22: 457-472; advance online publication, January 17, 2012; doi:10.1038/cr.2012.13
Autophagy: for better or for worse FREE
Ellen Wirawan, Tom Vanden Berghe, Saskia Lippens, Patrizia Agostinis and Peter Vandenabeele
Cell Res 22: 43-61; advance online publication, September 13, 2011; doi:10.1038/cr.2011.152
Original Articles
Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms FREE
Zhenlin Yang, Huanhuan Liang, Qian Zhou, Ying Li, Haiwei Chen, Wen Ye, Danying Chen, Joy Fleming, Hongbing Shu and Yingfang Liu
Cell Res 22: 1328-1338; advance online publication, July 24, 2012; doi:10.1038/cr.2012.111
Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies Open
Michael Steckel, Miriam Molina-Arcas, Britta Weigelt, Michaela Marani, Patricia H Warne, Hanna Kuznetsov, Gavin Kelly, Becky Saunders, Michael Howell, Julian Downward and David C Hancock
Cell Res 22: 1227-1245; advance online publication, May 22, 2012; doi:10.1038/cr.2012.82
Laminin/β1 integrin signal triggers axon formation by promoting microtubule assembly and stabilization FREE
Wen-Liang Lei, Shi-Ge Xing, Cai-Yun Deng, Xiang-Chun Ju, Xing-Yu Jiang and Zhen-Ge Luo
Cell Res 22: 954-972; advance online publication, March 20, 2012; doi:10.1038/cr.2012.40
Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein Open
Weijiao Huang, Wooyoung Choi, Wanqiu Hu, Na Mi, Qiang Guo, Meisheng Ma, Mei Liu, Yuan Tian, Peilong Lu, Feng-Liang Wang, Haiteng Deng, Lei Liu, Ning Gao, Li Yu and Yigong Shi
Cell Res 22: 473-489; advance online publication, February 7, 2012; doi:10.1038/cr.2012.24
Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature FREE
Huansheng Xu, B Alexander Yi, Hao Wu, Christoph Bock, Hongcang Gu, Kathy O Lui, Joo-Hye C Park, Ying Shao, Alyssa K Riley, Ibrahim J Domian, Erding Hu, Robert Willette, John Lepore, Alexander Meissner, Zhong Wang and Kenneth R Chien
Cell Res 22: 142-154; advance online publication, November 8, 2011, doi:10.1038/cr.2011.171
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA FREE
Lin Zhang, Dongxia Hou, Xi Chen, Donghai Li, Lingyun Zhu, Yujing Zhang, Jing Li, Zhen Bian, Xiangying Liang, Xing Cai, Yuan Yin, Cheng Wang, Tianfu Zhang, Dihan Zhu, Dianmu Zhang, Jie Xu, Qun Chen, Yi Ba, Jing Liu, Qiang Wang, Jianqun Chen, Jin Wang, Meng Wang, Qipeng Zhang, Junfeng Zhang, Ke Zen and Chen-Yu Zhang
Cell Res 22: 107-126; advance online publication, September 20, 2011; doi:10.1038/cr.2011.158