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Article |
Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin
- Yuxin Wang
- , Guopeng Wang
- , Yaxin Li
- , Qinyu Zhu
- , Hao Shen
- , Ning Gao
- & Junyu Xiao
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Research Highlight |
Forks in the road to the first hematopoietic stem cells
- Elizabeth D. Howell
- & Nancy A. Speck
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Review Article
| Open AccessInnate lymphoid cells control signaling circuits to regulate tissue-specific immunity
- Christoph S. N. Klose
- & David Artis
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Article
| Open AccessStructure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis
- Gaoxingyu Huang
- , Yanqing Zhang
- , Xuechen Zhu
- , Chao Zeng
- , Qifan Wang
- , Qiang Zhou
- , Qinghua Tao
- , Minhao Liu
- , Jianlin Lei
- , Chuangye Yan
- & Yigong Shi
-
Article
| Open AccessMolecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex
- Yanqing Zhang
- , Sai Li
- , Chao Zeng
- , Gaoxingyu Huang
- , Xuechen Zhu
- , Qifan Wang
- , Kunpeng Wang
- , Qiang Zhou
- , Chuangye Yan
- , Wusheng Zhang
- , Guangwen Yang
- , Minhao Liu
- , Qinghua Tao
- , Jianlin Lei
- & Yigong Shi
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Review Article
| Open AccessTranscriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases
- Naganari Ohkura
- & Shimon Sakaguchi
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Research Highlight |
A β-galactosidase kiss of death for senescent cells
- Xiaoqian Liu
- , Juan Carlos Izpisua Belmonte
- , Weiqi Zhang
- & Guang-Hui Liu
-
Article |
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer
- Shuo Wang
- , Yuan Qu
- , Pengyan Xia
- , Yi Chen
- , Xiaoxiao Zhu
- , Jing Zhang
- , Guan Wang
- , Yong Tian
- , Jianming Ying
- & Zusen Fan
-
Research Highlight |
Enabling anti-tumor immunity by unleashing ILC2
- Irene Mattiola
- & Andreas Diefenbach
-
Research Highlight |
ILC transdifferentiation: roles in cancer progression
- Maryam Ghaedi
- & Pamela S. Ohashi
-
Letter to the Editor
| Open AccessN6-methyladenine is incorporated into mammalian genome by DNA polymerase
- Xiaoling Liu
- , Weiyi Lai
- , Yao Li
- , Shaokun Chen
- , Baodong Liu
- , Ning Zhang
- , Jiezhen Mo
- , Cong Lyu
- , Jing Zheng
- , Ya-Rui Du
- , Guibin Jiang
- , Guo-Liang Xu
- & Hailin Wang
-
Article
| Open AccessThe ChinaMAP analytics of deep whole genome sequences in 10,588 individuals
- Yanan Cao
- , Lin Li
- , Min Xu
- , Zhimin Feng
- , Xiaohui Sun
- , Jieli Lu
- , Yu Xu
- , Peina Du
- , Tiange Wang
- , Ruying Hu
- , Zhen Ye
- , Lixin Shi
- , Xulei Tang
- , Li Yan
- , Zhengnan Gao
- , Gang Chen
- , Yinfei Zhang
- , Lulu Chen
- , Guang Ning
- , Yufang Bi
- , Weiqing Wang
- , Yifei Zhang
- , Yuhong Chen
- , Jianmin Liu
- , Jie Hong
- , Weiqiong Gu
- , Shu Wang
- , Hongyan Zhao
- , Xiuli Jiang
- , Aijing Shan
- , Qing Zhang
- , Wei Di
- , Qing Su
- , Xuefeng Yu
- , Guijun Qin
- , Qin Wan
- , Guixia Wang
- , Feixia Shen
- , Zuojie Luo
- , Yingfen Qin
- , Li Chen
- , Yanan Huo
- , Qiang Li
- , Chao Liu
- , Youmin Wang
- , Shengli Wu
- , Tao Yang
- , Huacong Deng
- , Jiajun Zhao
- , Yiming Mu
- , Limin Wang
- , Wenhua Zhao
- , Qiang Gao
- , Qiaoxiu Wang
- , Shengqing Wan
- , Fengyu Li
- , Xuanlin Huang
- , Xueyan Cheng
- , Peide Huang
- , Junmei Xu
- , Weining Hu
- , Guojia Zhang
- , Shizhi Luo
- , Chen Wang
- , Sha Liu
- , Hongyi Song
- , Yanhua Chen
- , Lishi Wang
- , Bing Zeng
- , Yu Liu
- , Siyu Wang
- , Jinbo Wu
- , Jia Guo
- , Rong Zhao
- , Lingyu Wu
- , Zewei Xiong
- & Mengyao Wang
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Article |
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells
- Xiaojing Liu
- , Tingting Liu
- , Yafang Shang
- , Pengfei Dai
- , Wubing Zhang
- , Brian J. Lee
- , Min Huang
- , Dingpeng Yang
- , Qiu Wu
- , Liu Daisy Liu
- , Xiaoqi Zheng
- , Bo O. Zhou
- , Junchao Dong
- , Leng-Siew Yeap
- , Jiazhi Hu
- , Tengfei Xiao
- , Shan Zha
- , Rafael Casellas
- , X. Shirley Liu
- & Fei-Long Meng
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Research Highlight |
COVID-19: treating and managing severe cases
- Jingwen Ai
- , Yang Li
- , Xian Zhou
- & Wenhong Zhang
-
Article
| Open AccessRegulation of sister chromatid cohesion by nuclear PD-L1
- Jia Yu
- , Bo Qin
- , Ann M. Moyer
- , Somaira Nowsheen
- , Xinyi Tu
- , Haidong Dong
- , Judy C. Boughey
- , Matthew P. Goetz
- , Richard Weinshilboum
- , Zhenkun Lou
- & Liewei Wang
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-
Research Highlight |
A new varietal of DNA interstrand crosslink repair
- Ravindra Amunugama
- & Johannes C. Walter
-
Letter to the Editor
| Open AccessPathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient
- Xiao-Hong Yao
- , Zhi-Cheng He
- , Ting-Yuan Li
- , Hua-Rong Zhang
- , Yan Wang
- , Huaming Mou
- , Qiaonan Guo
- , Shi-Cang Yu
- , Yanqing Ding
- , Xindong Liu
- , Yi-Fang Ping
- & Xiu-Wu Bian
-
Article
| Open AccessElimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice
- Yusheng Cai
- , Huanhuan Zhou
- , Yinhua Zhu
- , Qi Sun
- , Yin Ji
- , Anqi Xue
- , Yuting Wang
- , Wenhan Chen
- , Xiaojie Yu
- , Longteng Wang
- , Han Chen
- , Cheng Li
- , Tuoping Luo
- & Hongkui Deng
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Research Highlight |
Gasdermins deliver a deadly punch to cancer
- Cheng Shen
- , Abhimanu Pandey
- & Si Ming Man
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Article
| Open Accesss-HBEGF/SIRT1 circuit-dictated crosstalk between vascular endothelial cells and keratinocytes mediates sorafenib-induced hand–foot skin reaction that can be reversed by nicotinamide
- Peihua Luo
- , Hao Yan
- , Xueqin Chen
- , Ying Zhang
- , Ziying Zhao
- , Ji Cao
- , Yi Zhu
- , Jiangxia Du
- , Zhifei Xu
- , Xiaochen Zhang
- , Su Zeng
- , Bo Yang
- , Shenglin Ma
- & Qiaojun He
-
Letter to the Editor
| Open AccessStructural basis for gating mechanism of Pannexin 1 channel
- Luqiu Mou
- , Meng Ke
- , Mengxiao Song
- , Yuanyue Shan
- , Qingjie Xiao
- , Qingting Liu
- , Jialu Li
- , Ke Sun
- , Lei Pu
- , Li Guo
- , Jia Geng
- , Jianping Wu
- & Dong Deng
-
Correction |
Author Correction: Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and -C2
- Meisheng Ma
- , Jun-Jie Liu
- , Yan Li
- , Yuwei Huang
- , Na Ta
- , Yang Chen
- , Hua Fu
- , Ming-Da Ye
- , Yuehe Ding
- , Weijiao Huang
- , Jia Wang
- , Meng-Qiu Dong
- , Li Yu
- & Hong-Wei Wang
-
Research Highlight |
Proteasome phase separation: a novel layer of quality control
- Victoria Cohen-Kaplan
- , Ido Livneh
- & Aaron Ciechanover
-
Letter to the Editor |
Cryo-EM structures of human pannexin 1 channel
- Qiuheng Jin
- , Bo Zhang
- , Xiang Zheng
- , Ningning Li
- , Lingyi Xu
- , Yuan Xie
- , Fangjun Song
- , Eijaz Ahmed Bhat
- , Yuan Chen
- , Ning Gao
- , Jiangtao Guo
- , Xiaokang Zhang
- & Sheng Ye
-
Article |
Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies
- Yuting Wang
- , Guangyi Dai
- , Zhili Gu
- , Guopeng Liu
- , Ke Tang
- , Yi-Hsuan Pan
- , Yujie Chen
- , Xin Lin
- , Nan Wu
- , Haoshan Chen
- , Su Feng
- , Shou Qiu
- , Hongduo Sun
- , Qian Li
- , Chuan Xu
- , Yanan Mao
- , Yong Edward Zhang
- , Philipp Khaitovich
- , Yan-Ling Wang
- , Qunxiu Liu
- , Jing-Dong Jackie Han
- , Zhen Shao
- , Gang Wei
- , Chun Xu
- , Naihe Jing
- & Haipeng Li
-
Article
| Open AccessInhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
- Shuai Xia
- , Meiqin Liu
- , Chao Wang
- , Wei Xu
- , Qiaoshuai Lan
- , Siliang Feng
- , Feifei Qi
- , Linlin Bao
- , Lanying Du
- , Shuwen Liu
- , Chuan Qin
- , Fei Sun
- , Zhengli Shi
- , Yun Zhu
- , Shibo Jiang
- & Lu Lu
-
Letter to the Editor |
Base editing-mediated splicing correction therapy for spinal muscular atrophy
- Xiang Lin
- , Haizhu Chen
- , Ying-Qian Lu
- , Shunyan Hong
- , Xinde Hu
- , Yanxia Gao
- , Lu-Lu Lai
- , Jin-Jing Li
- , Zishuai Wang
- , Wenqin Ying
- , Lixiang Ma
- , Ning Wang
- , Erwei Zuo
- , Hui Yang
- & Wan-Jin Chen
-
Correction |
Author Correction: Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism
- Jia Wang
- , Xianqiang Song
- , Dandan Zhang
- , Xiaoqing Chen
- , Xun Li
- , Yaping Sun
- , Cui Li
- , Yunpeng Song
- , Yao Ding
- , Ruobing Ren
- , Essa Hu Harrington
- , Liaoyuan A. Hu
- , Wenge Zhong
- , Cen Xu
- , Xin Huang
- , Hong-Wei Wang
- & Yingli Ma
-
Letter to the Editor |
Cryo-EM structure of human bile salts exporter ABCB11
- Liang Wang
- , Wen-Tao Hou
- , Li Chen
- , Yong-Liang Jiang
- , Da Xu
- , Linfeng Sun
- , Cong-Zhao Zhou
- & Yuxing Chen
-
Article
| Open AccessEmbryonic endothelial evolution towards first hematopoietic stem cells revealed by single-cell transcriptomic and functional analyses
- Siyuan Hou
- , Zongcheng Li
- , Xiaona Zheng
- , Yun Gao
- , Ji Dong
- , Yanli Ni
- , Xiaobo Wang
- , Yunqiao Li
- , Xiaochen Ding
- , Zhilin Chang
- , Shuaili Li
- , Yuqiong Hu
- , Xiaoying Fan
- , Yu Hou
- , Lu Wen
- , Bing Liu
- , Fuchou Tang
- & Yu Lan
-
Letter to the Editor |
Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice
- Fangfang Han
- , Xiao Liu
- , Chuanfang Chen
- , Yinan Liu
- , Mingkun Du
- , Yu Zhou
- , Yong Liu
- , Bao-Liang Song
- , Housheng Hansen He
- & Yan Wang
-
Review Article
| Open AccessSignaling networks in immunometabolism
- Jordy Saravia
- , Jana L. Raynor
- , Nicole M. Chapman
- , Seon Ah Lim
- & Hongbo Chi
-
Research Highlight |
A separation that’s for the best: coming together at the PAS
- Wayne D. Hawkins
- & Daniel J. Klionsky
-
Letter to the Editor |
Cryo-EM structure of human heptameric Pannexin 1 channel
- Ronggui Qu
- , Lili Dong
- , Jilin Zhang
- , Xuekui Yu
- , Lei Wang
- & Shujia Zhu
-
Letter to the Editor |
Cryo-EM structure of full-length α-synuclein amyloid fibril with Parkinson’s disease familial A53T mutation
- Yunpeng Sun
- , Shouqiao Hou
- , Kun Zhao
- , Houfang Long
- , Zhenying Liu
- , Jing Gao
- , Yaoyang Zhang
- , Xiao-Dong Su
- , Dan Li
- & Cong Liu
-
Letter to the Editor
| Open AccessThe cell surface marker CD36 selectively identifies matured, mitochondria-rich hPSC-cardiomyocytes
- Ellen Ngar-Yun Poon
- , Xiao-ling Luo
- , Sarah E. Webb
- , Bin Yan
- , Rui Zhao
- , Stanley Chun Ming Wu
- , Yong Yang
- , Peng Zhang
- , Huajun Bai
- , Jiaofang Shao
- , Ching Man Chan
- , Godfrey Chi-Fung Chan
- , Suk Ying Tsang
- , Rebekah L. Gundry
- , Huang-Tian Yang
- & Kenneth R. Boheler
-
Letter to the Editor
| Open AccessGeneration of human hepatocytes from extended pluripotent stem cells
- Qiming Wang
- , Da Sun
- , Zhen Liang
- , Junyi Wang
- , Xinxing Zhong
- , Yulin Lyu
- , Junning Cao
- , Zhongqing Lin
- , Yuanyuan Du
- , Zhenchuan Miao
- , Shichun Lu
- , Cheng Li
- , Jun Xu
- , Yan Shi
- & Hongkui Deng
-
Review Article
| Open AccessToward targeting inflammasomes: insights into their regulation and activation
- Shelbi Christgen
- , David E. Place
- & Thirumala-Devi Kanneganti
-
-
Article
| Open AccessThe PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm
- Anne Ramat
- , Maria-Rosa Garcia-Silva
- , Camille Jahan
- , Rima Naït-Saïdi
- , Jérémy Dufourt
- , Céline Garret
- , Aymeric Chartier
- , Julie Cremaschi
- , Vipul Patel
- , Mathilde Decourcelle
- , Amandine Bastide
- , François Juge
- & Martine Simonelig
-
Review Article
| Open AccessTargeting immunometabolism as an anti-inflammatory strategy
- Eva M. Pålsson-McDermott
- & Luke A. J. O’Neill
-
Research Highlight |
First structural insights into CRISPR-Cas-guided DNA transposition
- John van der Oost
- & Ioannis Mougiakos
-
Article |
Rett syndrome-causing mutations compromise MeCP2-mediated liquid–liquid phase separation of chromatin
- Liang Wang
- , Mingli Hu
- , Mei-Qing Zuo
- , Jicheng Zhao
- , Di Wu
- , Li Huang
- , Yongxin Wen
- , Yunfan Li
- , Ping Chen
- , Xinhua Bao
- , Meng-Qiu Dong
- , Guohong Li
- & Pilong Li
-
-
Research Highlight |
Expanding the AtLAS of non-coding RNA functions in the brain
- Matthew J. Regier
- & Jason D. Shepherd
-
Article
| Open AccessMeningeal lymphatic vessels regulate brain tumor drainage and immunity
- Xueting Hu
- , Qiuping Deng
- , Lu Ma
- , Qingqing Li
- , Yidong Chen
- , Yuhan Liao
- , Fan Zhou
- , Chen Zhang
- , Linlin Shao
- , Jun Feng
- , Tubao He
- , Weihai Ning
- , Yan Kong
- , Yingqing Huo
- , Aibin He
- , Bing Liu
- , Jingjing Zhang
- , Ralf Adams
- , Yulong He
- , Fuchou Tang
- , Xiuwu Bian
- & Jincai Luo
-
Correction |
Author Correction: The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity
- Alexandra Schnell
- , Lloyd Bod
- , Asaf Madi
- & Vijay K. Kuchroo
-
Article |
In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids
- Yan Yuan
- , Laihua Li
- , Qing Cheng
- , Feiyang Diao
- , Qiao Zeng
- , Xiaoyu Yang
- , Yibo Wu
- , Hao Zhang
- , Mingqian Huang
- , Junqing Chen
- , Quan Zhou
- , Yunfei Zhu
- , Rong Hua
- , Jianyu Tian
- , Xin Wang
- , Zuomin Zhou
- , Jie Hao
- , Jinjin Yu
- , Dong Hua
- , Jiayin Liu
- , Xuejiang Guo
- , Qi Zhou
- & Jiahao Sha
