ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
November 11 2009 |
November 4 2009 |
September 30 2009 |
September 23 2009 |
September 2 2009 |
July 1 2009 |
February 20 2008 |
February 13 2008
November 18 2009
Practice
Intravenous-to-Oral Switch in Anticancer Chemotherapy: A Focus on Docetaxel and Paclitaxel
S L W Koolen, J H Beijnen and J H M Schellens
Clin Pharmacol Ther advance online publication, November 18, 2009; doi:10.1038/clpt.2009.233
State of the Art
Drug Uptake Systems in Liver and Kidney: A Historic Perspective
B Hagenbuch
Clin Pharmacol Ther advance online publication, November 18, 2009; doi:10.1038/clpt.2009.235
Articles
Effect of Simultaneous Induction and Inhibition of CYP3A by St John's Wort and Ritonavir on CYP3A Activity
V Hafner, M Jäger, A-K Matthée, R Ding, J Burhenne, W E Haefeli and G Mikus
Clin Pharmacol Ther advance online publication, November 18, 2009; doi:10.1038/clpt.2009.206
Clinical Pharmacokinetics of the BCR–ABL Tyrosine Kinase Inhibitor Nilotinib
C Tanaka, O Q P Yin, V Sethuraman, T Smith, X Wang, K Grouss, H Kantarjian, F Giles, O G Ottmann, L Galitz and H Schran
Clin Pharmacol Ther advance online publication, November 18, 2009; doi:10.1038/clpt.2009.208
November 11 2009
Translational Medicine
Transporters as Drug Targets: Discovery and Development of NPC1L1 Inhibitors
J L Betters and L Yu
Clin Pharmacol Ther advance online publication, November 11, 2009; doi:10.1038/clpt.2009.209
Articles
Selective Antagonism of Opioid-Induced Ventilatory Depression by an Ampakine Molecule in Humans Without Loss of Opioid Analgesia
B G Oertel, L Felden, P V Tran, M H Bradshaw, M S Angst, H Schmidt, S Johnson, J J Greer, G Geisslinger, M A Varney and J Lötsch
Clin Pharmacol Ther advance online publication, November 11, 2009; doi:10.1038/clpt.2009.194
High Frequency of Occurrence of CYP2D6 Gene Duplication/Multiduplication Indicating Ultrarapid Metabolism Among Suicide Cases
A L Zackrisson, B Lindblom and J Ahlner
Clin Pharmacol Ther advance online publication, November 11, 2009; doi:10.1038/clpt.2009.216
November 4 2009
Practice
Transporter Pharmacogenetics and Statin Toxicity
M Niemi
Clin Pharmacol Ther advance online publication, November 4, 2009; doi:10.1038/clpt.2009.197
Comparison of Critical Drug–Drug Interaction Listings: The Department of Veterans Affairs Medical System and Standard Reference Compendia
E L Olvey, S Clauschee and D C Malone
Clin Pharmacol Ther advance online publication, November 4, 2009; doi:10.1038/clpt.2009.198
Articles
The Role of Organic Anion–Transporting Polypeptides and Their Common Genetic Variants in Mycophenolic Acid Pharmacokinetics
N Picard, S W Yee, J-B Woillard, Y Lebranchu, Y Le Meur, K M Giacomini and P Marquet
Clin Pharmacol Ther advance online publication, November 4, 2009; doi:10.1038/clpt.2009.205
Articles
Safety and Pharmacokinetics of Repeat-Dose Micafungin in Young Infants
D K Benjamin Jr, P B Smith, A Arrieta, L Castro, P J Sánchez, D Kaufman, L J Arnold, L L Kovanda, T Sawamoto, D N Buell, W W Hope and T J Walsh
Clin Pharmacol Ther advance online publication, November 4, 2009; doi:10.1038/clpt.2009.200
A Pharmacovigilance Program From Laboratory Signals for the Detection and Reporting of Serious Adverse Drug Reactions in Hospitalized Patients
E Ramirez, A J Carcas, A M Borobia, S H Lei, E Piñana, S Fudio and J Frias
Clin Pharmacol Ther advance online publication, November 4, 2009; doi:10.1038/clpt.2009.185
Ocular Hemodynamic Effects of Nitrovasodilators in Healthy Subjects
D Schmidl, E Polska, B Kiss, S Sacu, G Garhofer and L Schmetterer
Clin Pharmacol Ther advance online publication, November 4, 2009; doi:10.1038/clpt.2009.186
September 30 2009
Articles
Genetic Factors (VKORC1, CYP2C9, EPHX1, and CYP4F2) Are Predictor Variables for Warfarin Response in Very Elderly, Frail Inpatients
E Pautas, C Moreau, I Gouin-Thibault, J-L Golmard, I Mahé, C Legendre, E Taillandier-Hériche, B Durand-Gasselin, A-M Houllier, P Verrier, P Beaune, M-A Loriot and V Siguret
Clin Pharmacol Ther advance online publication, September 30, 2009; doi:10.1038/clpt.2009.178
UDP-Glucuronosyltransferase (UGT) Polymorphisms Affect Atorvastatin Lactonization In Vitro and In Vivo
S Riedmaier, K Klein, U Hofmann, J E Keskitalo, P J Neuvonen, M Schwab, M Niemi and U M Zanger
Clin Pharmacol Ther advance online publication, September 30, 2009; doi:10.1038/clpt.2009.181
Loss-of-Function CYP2C9 Variants Improve Therapeutic Response to Sulfonylureas in Type 2 Diabetes: A Go-DARTS Study
K Zhou, L Donnelly, L Burch, R Tavendale, A S F Doney, G Leese, A T Hattersley, M I McCarthy, A D Morris, C C Lang, C N A Palmer and E R Pearson
Clin Pharmacol Ther advance online publication, September 30, 2009; doi:10.1038/clpt.2009.176
September 23 2009
Articles
Pharmacokinetics of Sulfadoxine and Pyrimethamine in Intermittent Preventive Treatment of Malaria in Pregnancy
M M Nyunt, I Adam, K Kayentao, J van Dijk, P Thuma, K Mauff, F Little, Y Cassam, E Guirou, B Traore, O Doumbo, D Sullivan, P Smith and K I Barnes
Clin Pharmacol Ther advance online publication, September 23, 2009; doi:10.1038/clpt.2009.177
September 2 2009
Letters to the Editor
Response to "Rupatadine and Heart Rhythm Disturbances"
A Carvajal, D Macías, I Salado, M Sáinz, S Ortega, C Campo, J García del Pozo, L H Martín Arias, A Velasco, S Gonçalves, R Pombal and R Carmona
Clin Pharmacol Ther advance online publication, September 2, 2009; doi:10.1038/clpt.2009.157
Rupatadine and Heart Rhythm Disturbances
R Fité and J Borja
Clin Pharmacol Ther advance online publication, September 2, 2009; doi:10.1038/clpt.2009.118
July 1 2009
Development
Transporters for Drug Delivery and as Drug Targets in Parasitic Protozoa
S M Landfear
Clin Pharmacol Ther advance online publication, July 1, 2009; doi:10.1038/clpt.2009.116
February 20 2008
Articles
Effects of Pregnancy on CYP3A and P-glycoprotein Activities as Measured by Disposition of Midazolam and Digoxin: A University of Washington Specialized Center of Research Study
MF Hebert, TR Easterling, B Kirby, DB Carr, ML Buchanan, T Rutherford, KE Thummel, DP Fishbein and JD Unadkat
Clin Pharmacol Ther advance online publication, February 20, 2008; doi:10.1038/sj.clpt.6100514
