Geriatrics
TABLE OF CONTENTS
Volume 85, Issue 1 (January 2009)
Editorial |
News & Views |
Perspectives |
Research |
Discovery & Development |
Regulation & Use |
Corrigenda
In This Issue
In This Issue
In This Issue FREE
Clin Pharmacol Ther 85: 1; doi:10.1038/clpt.2008.253
See also: Article by Madadi et al. See also: Article by Dispersyn et al. See also: Article by Hilmer & GnjidicSee also: Article by Laroche et al. See also: Article by HolmesEditorial
Editorial
Aging and Medications: Past, Present, Future FREE
JB Schwartz and DR Abernethy
Clin Pharmacol Ther 85: 3-10; doi:10.1038/clpt.2008.238
News & Views
Highlights
Highlights FREE
Clin Pharmacol Ther 85: 12-13; doi:10.1038/clpt.2008.255
ASCPT News
ASCPT News FREE
Clin Pharmacol Ther 85: 14-15; doi:10.1038/clpt.2008.249
Books
Dopamine Transporters: Chemistry, Biology, and Pharmacology FREE
Reviewed by SP David
Clin Pharmacol Ther 85: 16-17; doi:10.1038/clpt.2008.212
Perspectives
Commentaries
Mesenchymal Stem Cells and Neurodegenerative Disease FREE
AL Whone and NJ Scolding
Clin Pharmacol Ther 85: 19-20; doi:10.1038/clpt.2008.205
Safety Issues of Maternal Drug Therapy During Breastfeeding FREE
CM Berlin Jr, IM Paul and ES Vesell
Clin Pharmacol Ther 85: 20-22; doi:10.1038/clpt.2008.209
See also: Article by Madadi et al.Letters to the Editor
Influence of Lean Body Weight on Anticancer Drug Clearance FREE
RHJ Mathijssen and A Sparreboom
Clin Pharmacol Ther 85: 23; advance online publication, February 20, 2008; doi:10.1038/sj.clpt.6100511
See also: Letter to the Editor by Han et al.Response to "Influence of Lean Body Weight on Anticancer Drug Clearance" FREE
PY Han, SB Duffull, CMJ Kirkpatrick and B Green
Clin Pharmacol Ther 85: 24; advance online publication, October 22, 2008; doi:10.1038/clpt.2008.210
See also: Letter to the Editor by Mathijssen & SparreboomResearch
Report
The Consequence of Concomitantly Present Functional Genetic Variants for the Identification of Functional Genotype–Phenotype Associations in Pain FREE
J Lötsch, K Flühr, T Neddermayer, A Doehring and G Geisslinger
Clin Pharmacol Ther 85: 25-30; advance online publication, June 11, 2008; doi:10.1038/clpt.2008.103
Articles
Pharmacogenetics of Neonatal Opioid Toxicity Following Maternal Use of Codeine During Breastfeeding: A Case–Control Study FREE
P Madadi, CJD Ross, MR Hayden, BC Carleton, A Gaedigk, JS Leeder and G Koren
Clin Pharmacol Ther 85: 31-35; advance online publication, August 20, 2008; doi:10.1038/clpt.2008.157
See also: Commentary by Berlin et al.Promoter Polymorphisms in ACE (Angiotensin I–Converting Enzyme) Associated With Clinical Outcomes in Hypertension FREE
AD Johnson, Y Gong, D Wang, TY Langaee, J Shin, RM Cooper-DeHoff, NJ Schork, P Binkley, CJ Pepine, JA Johnson and W Sadee
Clin Pharmacol Ther 85: 36-44; advance online publication, October 22, 2008; doi:10.1038/clpt.2008.194
Genetic Variation in the CYP2D6 Gene Is Associated With a Lower Heart Rate and Blood Pressure in 
-Blocker Users FREE
MJ Bijl, LE Visser, RHN van Schaik, JA Kors, JCM Witteman, A Hofman, AG Vulto, T van Gelder and BHCh Stricker
Clin Pharmacol Ther 85: 45-50; advance online publication, September 10, 2008; doi:10.1038/clpt.2008.172
Desynchronization of Daily Rest–Activity Rhythm in the Days Following Light Propofol Anesthesia for Colonoscopy FREE
G Dispersyn, Y Touitou, O Coste, L Jouffroy, JC Lleu, E Challet and L Pain
Clin Pharmacol Ther 85: 51-55; advance online publication, September 17, 2008; doi:10.1038/clpt.2008.179
Population Pharmacokinetics of Sildenafil in Term Neonates: Evidence of Rapid Maturation of Metabolic Clearance in the Early Postnatal Period FREE
A Mukherjee, T Dombi, B Wittke and R Lalonde
Clin Pharmacol Ther 85: 56-63; advance online publication, September 17, 2008; doi:10.1038/clpt.2008.177
Dose–Response of Ritonavir on Hepatic CYP3A Activity and Elvitegravir Oral Exposure FREE
AA Mathias, S West, J Hui and BP Kearney
Clin Pharmacol Ther 85: 64-70; advance online publication, September 24, 2008; doi:10.1038/clpt.2008.168
The Pharmacokinetics and Bioavailability of Prochlorperazine Delivered as a Thermally Generated Aerosol in a Single Breath to Volunteers FREE
MJ Avram, DA Spyker, TK Henthorn and JV Cassella
Clin Pharmacol Ther 85: 71-77; advance online publication, October 1, 2008; doi:10.1038/clpt.2008.184
Elucidating Rifampin's Inducing and Inhibiting Effects on Glyburide Pharmacokinetics and Blood Glucose in Healthy Volunteers: Unmasking the Differential Effects of Enzyme Induction and Transporter Inhibition for a Drug and Its Primary Metabolite FREE
HX Zheng, Y Huang, LA Frassetto and LZ Benet
Clin Pharmacol Ther 85: 78-85; advance online publication, October 8, 2008; doi:10.1038/clpt.2008.186
Discovery & Development
Discovery
The Effects of Polypharmacy in Older Adults FREE
SN Hilmer and D Gnjidic
Clin Pharmacol Ther 85: 86-88; advance online publication, November 26, 2008; doi:10.1038/clpt.2008.224
Translational Medicine
The Critical Role of Clinical Pharmacology in Geriatric Psychopharmacology FREE
BG Pollock, CE Forsyth and RR Bies
Clin Pharmacol Ther 85: 89-93; advance online publication, November 26, 2008; doi:10.1038/clpt.2008.229
Development
Inappropriate Medications in the Elderly FREE
ML Laroche, JP Charmes, F Bouthier and L Merle
Clin Pharmacol Ther 85: 94-97; advance online publication, November 5, 2008; doi:10.1038/clpt.2008.214
Regulation & Use
Practice
Therapeutic/Pharmacologic Approaches to Urinary Incontinence in Older Adults FREE
CE DuBeau
Clin Pharmacol Ther 85: 98-102; advance online publication, November 26, 2008; doi:10.1038/clpt.2008.230
Public Policy
Rational Prescribing for Patients With a Reduced Life Expectancy FREE
HM Holmes
Clin Pharmacol Ther 85: 103-107; advance online publication, November 26, 2008; doi:10.1038/clpt.2008.211
Corrigenda
Corrigenda
CORRIGENDUM: Genetic Variation in Drug Transporters in Ethnic Populations FREE
Clin Pharmacol Ther 85: 108-109; doi:10.1038/clpt.2008.232
