TABLE OF CONTENTS
Volume 83, Issue 3 (March 2008)
Editorial |
News and Views |
Perspectives |
State of the Art |
Research |
Discovery & Development |
Regulation & Use
Contents
In This Issue
In This Issue
Clin Pharmacol Ther 83: 373; doi:10.1038/sj.clpt.6100521
See also: News and Views by Addis et al. See also: State of the Art by Cao & HendrixSee also: Articles by Mooney et al. See also: Articles by Caraco et al. See also: Articles by Gregorc et al.Editorial
Editorial
Pharmacoecology: A New Name for an Old Science
C Flexner
Clin Pharmacol Ther 83: 375-379; doi:10.1038/sj.clpt.6100499
News and Views
Highlights
News and Views
Clin Pharmacol Ther 83: 380-381; doi:10.1038/sj.clpt.6100522
ASCPT News
News and Views
Clin Pharmacol Ther 83: 382-383; doi:10.1038/sj.clpt.6100520
Books
Principles of Clinical Pharmacology, 2nd Edition
Reviewed by SG Carruthers
Clin Pharmacol Ther 83: 384-385; doi:10.1038/sj.clpt.6100485
Macroscopy
Special Cells, Special Considerations: The Challenges of Bringing Embryonic Stem Cells From the Laboratory to the Clinic
RC Addis, JWM Bulte and JD Gearhart
Clin Pharmacol Ther 83: 386-389; doi:10.1038/sj.clpt.6100384
Perspectives
Point/Counterpoint
Why the United States Still Needs Improved Dietary Supplement Regulation and Oversight
JD Morrow
Clin Pharmacol Ther 83: 391-393; doi:10.1038/sj.clpt.6100500
Should Herbal Medicines Be Regulated as Drugs?
M McGuffin
Clin Pharmacol Ther 83: 393-395; doi:10.1038/sj.clpt.6100480
Commentary
Drug–Drug Interaction Programs in Clinical Practice
PA Pham
Clin Pharmacol Ther 83: 396-398; doi:10.1038/sj.clpt.6100504
Forum
The Implications of Population Admixture in Race-based Drug Prescription
G Suarez-Kurtz
Clin Pharmacol Ther 83: 399-400; doi:10.1038/sj.clpt.6100308
Response to "The Implications of Population Admixture in Race-based Drug Prescription"
SS-J Lee
Clin Pharmacol Ther 83: 400; doi:10.1038/sj.clpt.6100372
State of the Art
State of the Art
Male Genital Tract Pharmacology: Developments in Quantitative Methods to Better Understand a Complex Peripheral Compartment
Y-J Cao and CW Hendrix
Clin Pharmacol Ther 83: 401-412; advance online publication, October 5, 2007; doi:10.1038/sj.clpt.6100342
Research
Communication
Chronopharmacokinetics of Oral Tegafur and Uracil in Colorectal Cancer Patients
M-C Etienne-Grimaldi, J-M Cardot, E François, N Renée, J-Y Douillard, E Gamelin and G Milano
Clin Pharmacol Ther 83: 413-415; advance online publication, July 18, 2007; doi:10.1038/sj.clpt.6100297
Articles
Effects of Genetic Variation in the Novel Organic Cation Transporter, OCTN1, on the Renal Clearance of Gabapentin
TJ Urban, C Brown, RA Castro, N Shah, R Mercer, Y Huang, CM Brett, EG Burchard and KM Giacomini
Clin Pharmacol Ther 83: 416-421; advance online publication, July 4, 2007; doi:10.1038/sj.clpt.6100271
Physical and Cognitive Performance and Burden of Anticholinergics, Sedatives, and ACE Inhibitors in Older Women
Y-J Cao, DE Mager, EM Simonsick, SN Hilmer, SM Ling, BG Windham, V Crentsil, S Yasar, LP Fried and DR Abernethy
Clin Pharmacol Ther 83: 422-429; advance online publication, August 22, 2007; doi:10.1038/sj.clpt.6100303
Intravenous Parecoxib Rapidly Leads to COX-2 Inhibitory Concentration of Valdecoxib in the Central Nervous System
V Mehta, A Johnston, R Cheung, A Bello and RM Langford
Clin Pharmacol Ther 83: 430-435; advance online publication, August 8, 2007; doi:10.1038/sj.clpt.6100304
Therapeutic Drug Monitoring of Nortriptyline in Smoking Cessation: A Multistudy Analysis FREE
ME Mooney, VI Reus, J Gorecki, SM Hall, GL Humfleet, RF Muñoz and K Delucchi
Clin Pharmacol Ther 83: 436-442; advance online publication, August 8, 2007; doi:10.1038/sj.clpt.6100307
Disease Severity Is a Major Determinant for the Pharmacodynamics of Propofol in Critically Ill Patients
MYM Peeters, LJ Bras, J DeJongh, RMJ Wesselink, LPHJ Aarts, M Danhof and CAJ Knibbe
Clin Pharmacol Ther 83: 443-451; advance online publication, August 8, 2007; doi:10.1038/sj.clpt.6100309
Pharmacokinetics of Meropenem Determined by Microdialysis in the Peritoneal Fluid of Patients With Severe Peritonitis Associated With Septic Shock
J Karjagin, S Lefeuvre, K Oselin, K Kipper, S Marchand, A Tikkerberi, J Starkopf, W Couet and RJ Sawchuk
Clin Pharmacol Ther 83: 452-459; advance online publication, August 8, 2007; doi:10.1038/sj.clpt.6100312
CYP2C9 Genotype-guided Warfarin Prescribing Enhances the Efficacy and Safety of Anticoagulation: A Prospective Randomized Controlled Study
Y Caraco, S Blotnick and M Muszkat
Clin Pharmacol Ther 83: 460-470; advance online publication, September 12, 2007; doi:10.1038/sj.clpt.6100316
The Effect of Herbal Medicine Baicalin on Pharmacokinetics of Rosuvastatin, Substrate of Organic Anion-transporting Polypeptide 1B1
L Fan, W Zhang, D Guo, Z-R Tan, P Xu, Q Li, Y-Z Liu, L Zhang, T-Y He, D-L Hu, D Wang and H-H Zhou
Clin Pharmacol Ther 83: 471-476; advance online publication, September 12, 2007; doi:10.1038/sj.clpt.6100318
Germline Polymorphisms in EGFR and Survival in Patients With Lung Cancer Receiving Gefitinib
V Gregorc, M Hidalgo, A Spreafico, G Cusatis, V Ludovini, RG Ingersoll, S Marsh, SM Steinberg, MG Viganò, D Ghio, E Villa, A Sparreboom and SD Baker
Clin Pharmacol Ther 83: 477-484; advance online publication, August 22, 2007; doi:10.1038/sj.clpt.6100320
Inter-rater Reliability of a Classification System for Hospital Adverse Drug Event Reports
K Haynes, S Hennessy, KH Morales, GA Gibson, C Barnhart, CK Jaipaul and DR Linkin
Clin Pharmacol Ther 83: 485-488; advance online publication, August 22, 2007; doi:10.1038/sj.clpt.6100322
Discovery & Development
Development
Use of ANOVA to Estimate Inter- and Intra-reader Variability for a Group of Readers in Thorough QT/QTc Studies
M Natekar, V Mahajan, A Satra, M O'Kelly and DR Karnad
Clin Pharmacol Ther 83: 489-491; advance online publication, January 9, 2008; doi:10.1038/sj.clpt.6100481
Regulation & Use
Practice
Perspectives From the Clinic: Will the Average Physician Embrace Personalized Medicine?
H Levy and JH Young
Clin Pharmacol Ther 83: 492-493; advance online publication, February 6, 2008; doi:10.1038/sj.clpt.6100486
Public Policy
The Effect of Globalization of Drug Manufacturing, Production, and Sourcing and Challenges for American Drug Safety
J Woo, S Wolfgang and H Batista
Clin Pharmacol Ther 83: 494-497; advance online publication, February 6, 2008; doi:10.1038/sj.clpt.6100493
