Practice

Clinical Pharmacology & Therapeutics (2008) 83, 3, 492–493.doi:10.1038/sj.clpt.6100486

Perspectives From the Clinic: Will the Average Physician Embrace Personalized Medicine?

H Levy1,2 and JH Young1,3

  1. 1Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
  2. 2McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland, USA
  3. 3Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

Correspondence: JH Young, (jhyoung@jhmi.edu)

Received 3 December 2007; Accepted 4 December 2007; Published online 6 February 2008.

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Abstract

In 1961, Richard Asher argued that the clinical question regarding a particular intervention is not "should it work?" but rather "does it work?". 1,2,3 Since that time, clinical trials have become the cornerstone of clinical science, providing physicians access to an expanding pharmacopeia of therapeutic options. The new capacity to change the course of illness has transformed patients' lives as well as the clinical encounter. The recent call for personalized medicine is an attempt to further our therapeutic effectiveness.

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