Women's Health
TABLE OF CONTENTS
Volume 83, Issue 1 (January 2008)
Editorial |
News and Views |
Perspectives |
State of the Art |
Research |
Discovery & Development |
Regulation & Use
In This Issue
In This Issue FREE
Clin Pharmacol Ther 83: 1; doi:10.1038/sj.clpt.6100465
See also: Point/Counterpoint by GreeneSee also: State of the Art by Moulder & HortobagyiSee also: Article by Lee et al. See also: Translational Medicine by Mount & GillilandSee also: Development by Stoch & WagnerEditorial
Advancing Women's Health in the 21st Century: Applying the Tools of Clinical Pharmacology FREE
K Uhl
Clin Pharmacol Ther 83: 3-7; doi:10.1038/sj.clpt.6100463
News and Views
Highlights
News and Views FREE
Clin Pharmacol Ther 83: 8-9; doi:10.1038/sj.clpt.6100466
ASCPT News
News and Views FREE
Clin Pharmacol Ther 83: 10-11; doi:10.1038/sj.clpt.6100464
Books
AMH (Australian Medicines Handbook, 2007 Edition) FREE
Reviewed by S E Tett
Clin Pharmacol Ther 83: 12-13; doi:10.1038/sj.clpt.6100429
Macroscopy
Postmenopausal Hormone Therapy for Disease Prevention: Have We Learned Any Lessons from the Past? FREE
J E Rossouw
Clin Pharmacol Ther 83: 14-16; doi:10.1038/sj.clpt.6100428
Perspectives
Point/Counterpoint
Emergency Contraception: A Reasonable Personal Choice or a Destructive Societal Influence? FREE
M F Greene
Clin Pharmacol Ther 83: 17-19; doi:10.1038/sj.clpt.6100433
Emergency Contraception: Overestimated Effectiveness and Questionable Expectations FREE
J B Stanford
Clin Pharmacol Ther 83: 19-21; doi:10.1038/sj.clpt.6100442
Commentaries
A Needed Information Source FREE
MC Frederiksen
Clin Pharmacol Ther 83: 22-23; doi:10.1038/sj.clpt.6100438
See also: Ethics by Chambers et al.Forum
Post-marketing Strategies for Medicines FREE
A Breckenridge
Clin Pharmacol Ther 83: 24-25; advance online publication, November 28, 2007; doi:10.1038/sj.clpt.6100427
Response to "Post-marketing Strategies for Medicines" FREE
A Goldhammer
Clin Pharmacol Ther 83: 25; advance online publication, December 5, 2007; doi:10.1038/sj.clpt.6100444
State of the Art
State of the Art
Advances in the Treatment of Breast Cancer FREE
S Moulder and GN Hortobagyi
Clin Pharmacol Ther 83: 26-36; advance online publication, December 19, 2007; doi:10.1038/sj.clpt.6100449
Coronary Heart Disease in Women: Update 2008 FREE
N K Wenger, L J Shaw and V Vaccarino
Clin Pharmacol Ther 83: 37-51; advance online publication, November 28, 2007; doi:10.1038/sj.clpt.6100447
Research
Articles
Cyclooxygenase Polymorphisms and Risk of Cardiovascular Events: The Atherosclerosis Risk in Communities (ARIC) Study FREE
C R Lee, K E North, M S Bray, D J Couper, G Heiss and D C Zeldin
Clin Pharmacol Ther 83: 52-60; advance online publication, May 9, 2007; doi:10.1038/sj.clpt.6100221
Supplementation With Goldenseal (Hydrastis canadensis), but not Kava Kava (Piper methysticum), Inhibits Human CYP3A Activity In Vivo FREE
B J Gurley, A Swain, M A Hubbard, F Hartsfield, J Thaden, D K Williams, W B Gentry and Y Tong
Clin Pharmacol Ther 83: 61-69; advance online publication, May 9, 2007; doi:10.1038/sj.clpt.6100222
Tumor Necrosis Factor-
Antagonism Improves Endothelial Dysfunction in Patients With Crohn's Disease FREE
F Schinzari, A Armuzzi, B De Pascalis, N Mores, M Tesauro, D Melina and C Cardillo
Clin Pharmacol Ther 83: 70-76; advance online publication, May 16, 2007; doi:10.1038/sj.clpt.6100229
Contribution of Itraconazole Metabolites to Inhibition of CYP3A4 In Vivo FREE
I E Templeton, K E Thummel, E D Kharasch, K L Kunze, C Hoffer, W L Nelson and N Isoherranen
Clin Pharmacol Ther 83: 77-85; advance online publication, May 9, 2007; doi:10.1038/sj.clpt.6100230
A Positron Emission Tomography Study to Assess Binding of Lecozotan, a Novel 5-Hydroxytryptamine-1A Silent Antagonist, to Brain 5-HT1A Receptors in Healthy Young and Elderly Subjects, and in Patients With Alzheimer's Disease FREE
S Raje, A A Patat, V Parks, L Schechter, A Plotka, J Paul and B Langstrom
Clin Pharmacol Ther 83: 86-96; advance online publication, May 16, 2007; doi:10.1038/sj.clpt.6100232
Quantitative Imaging and Sigmoidoscopy to Assess Distribution of Rectal Microbicide Surrogates FREE
C W Hendrix, E J Fuchs, K J Macura, L A Lee, T L Parsons, R P Bakshi, W A Khan, A Guidos, J P Leal and R Wahl
Clin Pharmacol Ther 83: 97-105; advance online publication, May 16, 2007; doi:10.1038/sj.clpt.6100236
Pharmacokinetics and Pharmacodynamics of the Novel Daily Rivastigmine Transdermal Patch Compared With Twice-daily Capsules in Alzheimer's Disease Patients FREE
G Lefèvre, G S
dek, S S Jhee, M T Leibowitz, H-La Huang, A Enz, S Maton, L Ereshefsky, F Pommier, H Schmidli and S Appel-Dingemanse
Clin Pharmacol Ther 83: 106-114; advance online publication, May 23, 2007; doi:10.1038/sj.clpt.6100242
Identification of Novel CYP2A6*1B Variants: The CYP2A6*1B Allele is Associated With Faster In Vivo Nicotine Metabolism FREE
J C Mwenifumbo, C N Lessov-Schlaggar, Q Zhou, R E Krasnow, G E Swan, N L Benowitz and R F Tyndale
Clin Pharmacol Ther 83: 115-121; advance online publication, May 23, 2007; doi:10.1038/sj.clpt.6100246
The Bradykinin Type 2 Receptor BE1 Polymorphism and Ethnicity Influence Systolic Blood Pressure and Vascular Resistance FREE
M M Pretorius, J V Gainer, G P Van Guilder, E B Coelho, J M Luther, P Fong, D D Rosenbaum, H A Malave, C Yu, M D Ritchie, D E Vaughan and N J Brown
Clin Pharmacol Ther 83: 122-129; advance online publication, May 23, 2007; doi:10.1038/sj.clpt.6100250
Mechanism-based Pharmacokinetic/Pharmacodynamic Meta-analysis of Trabectedin (ET-743, Yondelis) Induced Neutropenia FREE
J Hing, J J Perez-Ruixo, K Stuyckens, A Soto-Matos, L Lopez-Lazaro and P Zannikos
Clin Pharmacol Ther 83: 130-143; advance online publication, June 27, 2007; doi:10.1038/sj.clpt.6100259
Enhanced Buprenorphine Analgesia with the Addition of Ultra-low-dose Naloxone in Healthy Subjects FREE
S F La Vincente, J M White, A A Somogyi, F Bochner and C B Chapleo
Clin Pharmacol Ther 83: 144-152; advance online publication, June 13, 2007; doi:10.1038/sj.clpt.6100262
Ritonavir 100 mg Does Not Cause QTc Prolongation in Healthy Subjects: A Possible Role as CYP3A Inhibitor in Thorough QTc Studies FREE
N Sarapa, D J Nickens, S R Raber, R R Reynolds and M A Amantea
Clin Pharmacol Ther 83: 153-159; advance online publication, June 20, 2007; doi:10.1038/sj.clpt.6100263
Discovery & Development
Discovery
Tamoxifen Pharmacogenomics: The Role of CYP2D6 as a Predictor of Drug Response FREE
M P Goetz, A Kamal and M M Ames
Clin Pharmacol Ther 83: 160-166; advance online publication, September 19, 2007; doi:10.1038/sj.clpt.6100367
Translational Medicine
Emerging Biological Therapies in Systemic Lupus Erythematosus FREE
G R Mount and W R Gilliland
Clin Pharmacol Ther 83: 167-171; advance online publication, November 14, 2007; doi:10.1038/sj.clpt.6100436
Development
Cathepsin K Inhibitors: A Novel Target for Osteoporosis Therapy FREE
SA Stoch and JA Wagner
Clin Pharmacol Ther 83: 172-176; advance online publication, December 12, 2007; doi:10.1038/sj.clpt.6100450
Practice
Emergency Contraception Update: A Canadian Perspective FREE
V W Y Leung, J A Soon and M Levine
Clin Pharmacol Ther 83: 177-180; advance online publication, November 28, 2007; doi:10.1038/sj.clpt.6100443
Regulation & Use
Ethics
Drug Safety in Pregnant Women and Their Babies: Ignorance Not Bliss FREE
CD Chambers, JE Polifka and JM Friedman
Clin Pharmacol Ther 83: 181-183; advance online publication, December 12, 2007; doi:10.1038/sj.clpt.6100448
See also: Commentary by FrederiksenPharmacokinetic Studies in Pregnant Women FREE
G J Anger and M Piquette-Miller
Clin Pharmacol Ther 83: 184-187; advance online publication, September 19, 2007; doi:10.1038/sj.clpt.6100377
Public Policy
Looking at Research Through a Different Lens: The Canadian Institute of Gender and Health FREE
J D Gray and M J Stewart
Clin Pharmacol Ther 83: 188-191; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100432
