Vaccines

TABLE OF CONTENTS

Volume 82, Issue 6 (December 2007)

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In This Issue

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Editorial

Pharmacology, Vaccinomics, and the Second Golden Age of Vaccinology

G A Poland

Clin Pharmacol Ther 82: 623-626; doi:10.1038/sj.clpt.6100379

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News and Views

Highlights

News and Views

Clin Pharmacol Ther 82: 628-629; doi:10.1038/sj.clpt.6100440

ASCPT News

News and Views

Clin Pharmacol Ther 82: 630-631; doi:10.1038/sj.clpt.6100439

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Perspectives

Point/Counterpoint

Pandemic Flu Vaccine: Are We Doing Enough?

J D Campbell

Clin Pharmacol Ther 82: 633-635; doi:10.1038/sj.clpt.6100417

Pandemic Influenza Vaccine: The US Government Is Not Doing Enough

M T Osterholm

Clin Pharmacol Ther 82: 635-637; doi:10.1038/sj.clpt.6100421

Commentaries

The Importance of Including Swine and Poultry Workers in Influenza Vaccination Programs

G C Gray and W S Baker

Clin Pharmacol Ther 82: 638-641; doi:10.1038/sj.clpt.6100391

Use of Nanocarriers for Transdermal Vaccine Delivery

L B Lawson, L C Freytag and J D Clements

Clin Pharmacol Ther 82: 641-643; doi:10.1038/sj.clpt.6100425

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State of the Art

State of the Art

Mass Spectrometry and Peptide-based Vaccine Development

I G Ovsyannikova, K L Johnson, H R Bergen III and G A Poland

Clin Pharmacol Ther 82: 644-652; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100389

Heterogeneity in Vaccine Immune Response: The Role of Immunogenetics and the Emerging Field of Vaccinomics

G A Poland, I G Ovsyannikova, R M Jacobson and D I Smith

Clin Pharmacol Ther 82: 653-664; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100415

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Research

Articles

New Pre-pandemic Influenza Vaccines: An Egg- and Adjuvant-independent Human Adenoviral Vector Strategy Induces Long-lasting Protective Immune Responses in Mice

M A Hoelscher, L Jayashankar, S Garg, V Veguilla, X Lu, N Singh, J M Katz, S K Mittal and S Sambhara

Clin Pharmacol Ther 82: 665-671; advance online publication, October 24, 2007; doi:10.1038/sj.clpt.6100418

Heterologous Prime–Boost Strategy to Immunize Very Young Infants against Measles: Pre-clinical Studies in Rhesus Macaques

M F Pasetti, A Resendiz-Albor, K Ramirez, R Stout, M Papania, R J Adams, F P Polack, B J Ward, D Burt, S Chabot, J Ulmer, E M Barry and M M Levine

Clin Pharmacol Ther 82: 672-685; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100420

HIV/AIDS Vaccines: 2007

H L Robinson

Clin Pharmacol Ther 82: 686-693; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100408

White Blood Cell Telomerase Activity and Incident Respiratory Illness Among Community-Dwelling Elderly Vaccinated Against Seasonal Influenza

P V Targonski, C R Caldwell, M Strausbauch, P Wettstein, G A Poland and E G Tangalos

Clin Pharmacol Ther 82: 694-699; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100410

Preclinical Pharmacology and Toxicology of Intravenous MV-NIS, an Oncolytic Measles Virus Administered With or Without Cyclophosphamide

R M Myers, S M Greiner, M E Harvey, G Griesmann, M J Kuffel, S A Buhrow, J M Reid, M Federspiel, M M Ames, D Dingli, K Schweikart, A Welch, A Dispenzieri, K-W Peng and S J Russell

Clin Pharmacol Ther 82: 700-710; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100409

CYP3A5 and CYP3A4 but not MDR1 Single-nucleotide Polymorphisms Determine Long-term Tacrolimus Disposition and Drug-related Nephrotoxicity in Renal Recipients

D R J Kuypers, H de Jonge, M Naesens, E Lerut, K Verbeke and Y Vanrenterghem

Clin Pharmacol Ther 82: 711-725; advance online publication, May 9, 2007; doi:10.1038/sj.clpt.6100216

Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

M K Pasanen, H Fredrikson, P J Neuvonen and M Niemi

Clin Pharmacol Ther 82: 726-733; advance online publication, May 2, 2007; doi:10.1038/sj.clpt.6100220

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Discovery & Development

Discovery

Cancer Mucosa Antigens as a Novel Immunotherapeutic Class of Tumor-associated Antigen

A E Snook, L C Eisenlohr, J L Rothstein and S A Waldman

Clin Pharmacol Ther 82: 734-739; advance online publication, September 26, 2007; doi:10.1038/sj.clpt.6100369

MF59 Is a Safe and Potent Vaccine Adjuvant for Flu Vaccines in Humans: What Did We Learn During Its Development?

D T O'Hagan, A Wack and A Podda

Clin Pharmacol Ther 82: 740-744; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100402

Translational Medicine

Translational Research on Vaccines: Influenza as an Example

R B Belshe

Clin Pharmacol Ther 82: 745-749; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100419

Development

Vaccine Immunopotentiators of the Future

V E J C Schijns and W G J Degen

Clin Pharmacol Ther 82: 750-755; advance online publication, October 3, 2007; doi:10.1038/sj.clpt.6100394

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Regulation & Use

Practice

Vaccines and Autism: Evidence Does Not Support a Causal Association

F DeStefano

Clin Pharmacol Ther 82: 756-759; advance online publication, October 10, 2007; doi:10.1038/sj.clpt.6100407

Ethics

Lessons from the Failure of Human Papillomavirus Vaccine State Requirements

J L Schwartz, A L Caplan, R R Faden and J Sugarman

Clin Pharmacol Ther 82: 760-763; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100397

Public Policy

Financing Immunization of Adults in the United States

W A Orenstein, G T Mootrey, K Pazol and A R Hinman

Clin Pharmacol Ther 82: 764-768; advance online publication, October 31, 2007; doi:10.1038/sj.clpt.6100401

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