Regenerative Pharmacology

TABLE OF CONTENTS

Volume 82, Issue 3 (September 2007)

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Contents

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Editorial

Evolution of Clinical Pharmacology and Therapeutics

S A Waldman, N B Christensen and A Terzic

Clin Pharmacol Ther 82: 233-235; doi:10.1038/sj.clpt.6100314

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News and Views

Highlights

News and Views

Clin Pharmacol Ther 82: 236-237; doi:10.1038/sj.clpt.6100341

ASCPT News

ASCPT News

Clin Pharmacol Ther 82: 238-239; doi:10.1038/sj.clpt.6100339

Macroscopy

Fragmentation: When Pulling Apart All Comes Together

N B Christensen

Clin Pharmacol Ther 82: 240; doi:10.1038/sj.clpt.6100315

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Perspectives

Commentaries

"Stemness" Does Not Explain the Repair of Many Tissues by Mesenchymal Stem/Multipotent Stromal Cells (MSCs)

D J Prockop

Clin Pharmacol Ther 82: 241-243; doi:10.1038/sj.clpt.6100313

The Star-Allele Nomenclature: Retooling for Translational Genomics

J D Robarge, L Li, Z Desta, A Nguyen and D A Flockhart

Clin Pharmacol Ther 82: 244-248; doi:10.1038/sj.clpt.6100284

Protease Inhibitors as Immunomodulatory Drugs for HIV Infection

S G Deeks

Clin Pharmacol Ther 82: 248-250; doi:10.1038/sj.clpt.6100205

See also: Article by Vlahakis et al.

Forum

Nicotine Intake and Steady-state Cotinine when Smoking Cigarettes of Different Yields

P Zuccaro, R Pacifici and S Pichini

Clin Pharmacol Ther 82: 251; doi:10.1038/sj.clpt.6100147

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State of the Art

State of the Art

Stem Cells: A Revolution in Therapeutics—Recent Advances in Stem Cell Biology and Their Therapeutic Applications in Regenerative Medicine and Cancer Therapies

M Mimeault, R Hauke and S K Batra

Clin Pharmacol Ther 82: 252-264; advance online publication, August 1, 2007; doi:10.1038/sj.clpt.6100301

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Research

Articles

Selective Induction of Human Hepatic Cytochromes P450 2B6 and 3A4 by Metamizole

T Saussele, O Burk, J K Blievernicht, K Klein, A Nussler, N Nussler, J G Hengstler, M Eichelbaum, M Schwab and U M Zanger

Clin Pharmacol Ther 82: 265-274; advance online publication, March 7, 2007; doi:10.1038/sj.clpt.6100138

Reduction in Hematocrit and Hemoglobin Following Pioglitazone Treatment is not Hemodilutional in Type II Diabetes Mellitus

R Berria, L Glass, A Mahankali, Y Miyazaki, A Monroy, E De Filippis, K Cusi, E Cersosimo, R A DeFronzo and A Gastaldelli

Clin Pharmacol Ther 82: 275-281; advance online publication, March 14, 2007; doi:10.1038/sj.clpt.6100146

Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with Antidotes

F J Ekström, C Åstot and Y-P Pang

Clin Pharmacol Ther 82: 282-293; advance online publication, April 18, 2007; doi:10.1038/sj.clpt.6100151

Flying in the Face of Resistance: Antiviral-independent Benefit of HIV Protease Inhibitors on T-cell Survival

S R Vlahakis, G D Bren, A Algeciras-Schimnich, S A Trushin, D J Schnepple and A D Badley

Clin Pharmacol Ther 82: 294-299; advance online publication, March 14, 2007; doi:10.1038/sj.clpt.6100140

Genetic Variation in the Renal Sodium Transporters NKCC2, NCC, and ENaC in Relation to the Effects of Loop Diuretic Drugs

S V Vormfelde, D Sehrt, M R Toliat, M Schirmer, I Meineke, M Tzvetkov, P Nürnberg and J Brockmöller

Clin Pharmacol Ther 82: 300-309; advance online publication, April 25, 2007; doi:10.1038/sj.clpt.6100131

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Discovery & Development

Discovery

Human Embryonic Stem Cell Derivation and Nuclear Transfer: Impact on Regenerative Therapeutics and Drug Discovery

R P Cervera and M Stojkovic

Clin Pharmacol Ther 82: 310-315; advance online publication, June 27, 2007; doi:10.1038/sj.clpt.6100278

Translational Medicine

Pharmacoproteomics: Advancing the Efficacy and Safety of Regenerative Therapeutics

D K Arrell, N J Niederländer, C Perez-Terzic, S Chung, A Behfar and A Terzic

Clin Pharmacol Ther 82: 316-319; advance online publication, August 1, 2007; doi:10.1038/sj.clpt.6100310

Development

Infrastructure Development for Human Cell Therapy Translation

A B Dietz, D J Padley and D A Gastineau

Clin Pharmacol Ther 82: 320-324; advance online publication, July 18, 2007; doi:10.1038/sj.clpt.6100288

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Regulation & Use

Practice

Current Status of Allogeneic Stem Cell Transplantation for Treatment of Hematologic Malignancies

D P Hart and K S Peggs

Clin Pharmacol Ther 82: 325-329; advance online publication, July 18, 2007; doi:10.1038/sj.clpt.6100283

Ethics

Stem Cell Science: Current Ethical and Policy Issues

A Mauron and M E Jaconi

Clin Pharmacol Ther 82: 330-333; advance online publication, July 18, 2007; doi:10.1038/sj.clpt.6100295

Public Policy

New Programs for Gene- and Cell-based Therapies at NHLBI

S I Skarlatos

Clin Pharmacol Ther 82: 334-336; advance online publication, July 11, 2007; doi:10.1038/sj.clpt.6100289

Education

Embryonic Stem Cells: From Bench to Bedside

M Pucéat and A Ballis

Clin Pharmacol Ther 82: 337-339; advance online publication, July 18, 2007; doi:10.1038/sj.clpt.6100298

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Erratum

ERRATUM: ASCPT News FREE

Clin Pharmacol Ther 82: 340; doi:10.1038/sj.clpt.6100351

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