Bridging Discovery and Practice

TABLE OF CONTENTS

Volume 81, Issue 6 (June 2007)

Top

Contents

Top

Editorial

Clinical Pharmacology: Bridging Discovery and Practice

R J Hohl

Clin Pharmacol Ther 81: 783-785; doi:10.1038/sj.clpt.6100225

Top

News and Views

Highlights

Highlights

Clin Pharmacol Ther 81: 786-787; doi:10.1038/sj.clpt.6100217

ASCPT News

ASCPT News

Clin Pharmacol Ther 81: 788-789; doi:10.1038/sj.clpt.6100218

Books

The Merck Manual, 18th Edition

S A Waldman and A Terzic

Clin Pharmacol Ther 81: 790-791; doi:10.1038/sj.clpt.6100186

Macroscopy

In Vivo Molecular Imaging Biomarkers: Clinical Pharmacology's new "PET"?

R Nutt, L J Vento and M H T Ridinger

Clin Pharmacol Ther 81: 792-795; doi:10.1038/sj.clpt.6100213

Top

Perspectives

Commentaries

Prosecution of Physicians for Prescribing Opioids to Patients

D M Benjamin

Clin Pharmacol Ther 81: 797-798; doi:10.1038/sj.clpt.6100115

See also: Public Policy by Reidenberg & Willis
Can State Medical Boards Adequately Respond to Reports that Physicians Are Inappropriately Prescribing Opioids?

D E Hoffmann

Clin Pharmacol Ther 81: 799-801; doi:10.1038/sj.clpt.6100209

See also: Public Policy by Reidenberg & Willis
"Personalized Medicine: Elusive Dream or Imminent Reality?": A Commentary

A Roses

Clin Pharmacol Ther 81: 801-805; doi:10.1038/sj.clpt.6100227

See also: State of the Art by Lesko
The DEA's Balancing Act to Ensure Public Health and Safety

J T Rannazzisi

Clin Pharmacol Ther 81: 805-806; doi:10.1038/sj.clpt.6100212

See also: Public Policy by Reidenberg & Willis
Top

State of the Art

State of the Art

Personalized Medicine: Elusive Dream or Imminent Reality?

L J Lesko

Clin Pharmacol Ther 81: 807-816; doi:10.1038/sj.clpt.6100204

Top

Research

Communications

Identification and Characterization of CYP2D6*56B, an Allele Associated with the Poor Metabolizer Phenotype

A Gaedigk, J D Eklund, R E Pearce, J S Leeder, S W Alander, M S Phillips, L D Bradford and M J Kennedy

Clin Pharmacol Ther 81: 817-820; advance online publication, March 28, 2007; doi:10.1038/sj.clpt.6100125

Articles

Pharmacokinetics of Quetiapine in Overdose and the Effect of Activated Charcoal

G K Isbister, L E Friberg, L P Hackett and S B Duffull

Clin Pharmacol Ther 81: 821-827; advance online publication, April 4, 2007; doi:10.1038/sj.clpt.6100193

Effects of Uptake and Efflux Transporter Inhibition on Erythromycin Breath Test Results

L A Frassetto, S Poon, C Tsourounis, C Valera and L Z Benet

Clin Pharmacol Ther 81: 828-832; advance online publication, March 14, 2007; doi:10.1038/sj.clpt.6100148

Effects of Daily Ingestion of Cranberry Juice on the Pharmacokinetics of Warfarin, Tizanidine, and Midazolam—Probes of CYP2C9, CYP1A2, and CYP3A4

J J Lilja, J T Backman and P J Neuvonen

Clin Pharmacol Ther 81: 833-839; advance online publication, March 28, 2007; doi:10.1038/sj.clpt.6100149

Disposition of Acetaminophen at 4, 6, and 8 g/day for 3 Days in Healthy Young Adults

C K Gelotte, J F Auiler, J M Lynch, A R Temple and J T Slattery

Clin Pharmacol Ther 81: 840-848; advance online publication, March 21, 2007; doi:10.1038/sj.clpt.6100121

Suppression of Niacin-induced Vasodilation with an Antagonist to Prostaglandin D2 Receptor Subtype 1

E Lai, I De Lepeleire, T M Crumley, F Liu, L A Wenning, N Michiels, E Vets, G O'Neill, J A Wagner and K Gottesdiener

Clin Pharmacol Ther 81: 849-857; advance online publication, March 28, 2007; doi:10.1038/sj.clpt.6100180

Pharmacokinetics and Pharmacodynamics of the Dual FII/FX Inhibitor BIBT 986 in Endotoxin-induced Coagulation

J M Leitner, B Jilma, F B Mayr, F Cardona, A O Spiel, C Firbas, K Rathgen, H Stähle, U Schühly and E U Graefe-Mody

Clin Pharmacol Ther 81: 858-866; advance online publication, April 4, 2007; doi:10.1038/sj.clpt.6100153

Ganciclovir Population Pharmacokinetics in Neonates Following Intravenous Administration of Ganciclovir and Oral Administration of a Liquid Valganciclovir Formulation

E P Acosta, R C Brundage, J R King, P J Sánchez, S Sood, V Agrawal, J Homans, R F Jacobs, D Lang, J R Romero, J Griffin, G Cloud, R Whitley and D W Kimberlin for the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group

Clin Pharmacol Ther 81: 867-872; advance online publication, March 28, 2007; doi:10.1038/sj.clpt.6100150

Change in Erythropoietin Pharmacokinetics Following Hematopoietic Transplantation

J A Widness, R L Schmidt, R J Hohl, F D Goldman, N H Al-Huniti, K J Freise and P Veng-Pedersen

Clin Pharmacol Ther 81: 873-879; advance online publication, April 11, 2007; doi:10.1038/sj.clpt.6100165

Top

Discovery & Development

Discovery

Nuclear Transport: Target for Therapy

R S Faustino, T J Nelson, A Terzic and C Perez-Terzic

Clin Pharmacol Ther 81: 880-886; advance online publication, April 18, 2007; doi:10.1038/sj.clpt.6100141

Translational Medicine

Developing Strategies to Link Basic Cardiovascular Sciences with Clinical Drug Development: Another Opportunity for Translational Sciences

A M Feldman, W J Koch and T L Force

Clin Pharmacol Ther 81: 887-892; advance online publication, March 28, 2007; doi:10.1038/sj.clpt.6100160

Development

Symmetric Division of Cancer Stem Cells – a Key Mechanism in Tumor Growth that should be Targeted in Future Therapeutic Approaches

B M Boman, M S Wicha, J Z Fields and O A Runquist

Clin Pharmacol Ther 81: 893-898; advance online publication, April 25, 2007; doi:10.1038/sj.clpt.6100202

Top

Regulation & Use

Practice

The Convergence of Conventional Therapeutic Drug Monitoring and Pharmacogenetic Testing in Personalized Medicine: Focus on Antidepressants

F Sjöqvist and E Eliasson

Clin Pharmacol Ther 81: 899-902; advance online publication, March 28, 2007; doi:10.1038/sj.clpt.6100188

Public Policy

Prosecution of Physicians for Prescribing Opioids to Patients

M M Reidenberg and O Willis

Clin Pharmacol Ther 81: 903-906; advance online publication, February 28, 2007; doi:10.1038/sj.clpt.6100127

Education

Clinical Pharmacology Education and Training at the National Institutes of Health

J J L Lertora and A J Atkinson Jr

Clin Pharmacol Ther 81: 907-909; advance online publication, April 11, 2007; doi:10.1038/sj.clpt.6100206

Top

Errata

Future of Pediatric Therapeutics: Reauthorization of BPCA and PREA FREE

R M Ward and R Kauffman

Clin Pharmacol Ther 81: 910; doi:10.1038/sj.clpt.6100244

Pharmacotherapy for the Treatment of Patients with Type 2 Diabetes Mellitus: Rationale and Specific Agents FREE

W T Cefalu

Clin Pharmacol Ther 81: 910; doi:10.1038/sj.clpt.6100245

Extra navigation

.

naturejobs

ADVERTISEMENT