Personalized Medicine
TABLE OF CONTENTS
Volume 81, Issue 3 (March 2007)
Editorial |
News and Views |
Perspectives |
State of the Art |
Research |
Discovery & Development |
Regulation & Use |
Erratum
Contents
Contents
In this issue FREE
Clin Pharmacol Ther 81: 309; doi:10.1038/sj.clpt.6100113
See also: Macroscopy by RatainSee also: State of the Art by Giacomini et al. See also: Article by Glaeser et al. See also: Article by Ghibellini et al. See also: Public Policy by LongSee also: Education by Wilson-Pauwels et al.Editorial
Editorial
The Art and Science of Personalized Medicine
M Piquette-Miller and D M Grant
Clin Pharmacol Ther 81: 311-315; doi:10.1038/sj.clpt.6100130
News and Views
Highlights
Highlights
Clin Pharmacol Ther 81: 316-317; doi:10.1038/sj.clpt.6100114
ASCPT News
ASCPT News
Clin Pharmacol Ther 81: 318-319; doi:10.1038/sj.clpt.6100111
Macroscopy
Personalized Medicine: Building the GPS to Take Us There FREE
M J Ratain
Clin Pharmacol Ther 81: 321-322; doi:10.1038/sj.clpt.6100092
Perspectives
Commentaries
Enhancing Race-Based Prescribing Precision with Pharmacogenomics
A Nguyen, Z Desta and D A Flockhart
Clin Pharmacol Ther 81: 323-325; doi:10.1038/sj.clpt.6100080
Letters to the Editor
Acute Effects of Sibutramine Administration on the Autonomic Nervous System in Obese Subjects
Fuad Lechin and Bertha van der Dijs
Clin Pharmacol Ther 81: 326; doi:10.1038/sj.clpt.6100065
Response to "Acute Effects of Sibutramine Administration on the Autonomic Nervous System in obese Subjects"
Jens Jordan and Karsten Heusser
Clin Pharmacol Ther 81: 326-327; advance online publication, January 24, 2007; doi:10.1038/sj.clpt.6100066
State of the Art
The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response FREE
K M Giacomini, C M Brett, R B Altman, N L Benowitz, M E Dolan, D A Flockhart, J A Johnson, D F Hayes, T Klein, R M Krauss, D L Kroetz, H L McLeod, A T Nguyen, M J Ratain, M V Relling, V Reus, D M Roden, C A Schaefer, A R Shuldiner, T Skaar, K Tantisira, R F Tyndale, L Wang, R M Weinshilboum, S T Weiss and I Zineh for the Pharmacogenetics Research Network
Clin Pharmacol Ther 81: 328-345; doi:10.1038/sj.clpt.6100087
Research
Articles
Influence of Ethanol and Gender on Methylphenidate Pharmacokinetics and Pharmacodynamics
K S Patrick, A B Straughn, R R Minhinnett, S D Yeatts, A E Herrin, C L DeVane, R Malcolm, G C Janis and J S Markowitz
Clin Pharmacol Ther 81: 346-353; doi:10.1038/sj.clpt.6100082
Gene Modulatory Effects, Pharmacokinetics, and Clinical Tolerance of Interferon-
1b: A Second Member of the Interferon- Family
P Masci, T Olencki, L Wood, L Rybicki, B Jacobs, B Williams, P Faber, R Bukowski, K Tong and E C Borden
Clin Pharmacol Ther 81: 354-361; doi:10.1038/sj.clpt.6100081
Intestinal Drug Transporter Expression and the Impact of Grapefruit Juice in Humans FREE
H Glaeser, D G Bailey, G K Dresser, J C Gregor, U I Schwarz, J S McGrath, E Jolicoeur, W Lee, B F Leake, R G Tirona and R B Kim
Clin Pharmacol Ther 81: 362-370; advance online publication, January 10, 2007; doi:10.1038/sj.clpt.6100056
Effects of Supportive Treatment such as Antioxidant or Leukotriene Receptor Antagonist Drugs on Inflammatory and Respiratory Parameters in Asthma Patients
T Tug, A Godekmerdan, N Sari, F Karatas and E S Erdem
Clin Pharmacol Ther 81: 371-376; doi:10.1038/sj.clpt.6100091
Thorough QT Study with Recommended and Supratherapeutic Doses of Tolterodine
B K Malhotra, P Glue, K Sweeney, R Anziano, J Mancuso and P Wicker
Clin Pharmacol Ther 81: 377-385; doi:10.1038/sj.clpt.6100089
Association of CYP3A5 Polymorphisms with Hypertension and Antihypertensive Response to Verapamil
T Y Langaee, Y Gong, H N Yarandi, D A Katz, R M Cooper-DeHoff, C J Pepine and J A Johnson
Clin Pharmacol Ther 81: 386-391; doi:10.1038/sj.clpt.6100090
The Impact of UGT1A8, UGT1A9, and UGT2B7 Genetic Polymorphisms on the Pharmacokinetic Profile of Mycophenolic Acid After a Single Oral Dose in Healthy Volunteers
E Lévesque, R Delage, M-O Benoit-Biancamano, P Caron, O Bernard, F Couture and C Guillemette
Clin Pharmacol Ther 81: 392-400; doi:10.1038/sj.clpt.6100073
Safety and Pharmacokinetics of Paracetamol Following Intravenous Administration of 5 g During the First 24 h with a 2-g Starting Dose
N Gregoire, L Hovsepian, V Gualano, E Evene, G Dufour and A Gendron
Clin Pharmacol Ther 81: 401-405; doi:10.1038/sj.clpt.6100064
In Vitro–In Vivo Correlation of Hepatobiliary Drug Clearance in Humans
G Ghibellini, L S Vasist, E M Leslie, W D Heizer, R J Kowalsky, B F Calvo and K L R Brouwer
Clin Pharmacol Ther 81: 406-413; advance online publication, January 18, 2007; doi:10.1038/sj.clpt.6100059
Inhibitory and Inductive Effects of Rifampin on the Pharmacokinetics of Bosentan in Healthy Subjects
P L M van Giersbergen, A Treiber, R Schneiter, H Dietrich and J Dingemanse
Clin Pharmacol Ther 81: 414-419; advance online publication, January 24, 2007; doi:10.1038/sj.clpt.6100075
Discovery & Development
Translational Medicine
Molecular Imaging as a Tool for Personalized and Targeted Anticancer Therapy
K McLarty and R M Reilly
Clin Pharmacol Ther 81: 420-424; doi:10.1038/sj.clpt.6100096
Development
Should Pharmacogenomic Studies be Required for New Drug Approval?
M V Relling and J M Hoffman
Clin Pharmacol Ther 81: 425-428; doi:10.1038/sj.clpt.6100097
Regulation & Use
Practice
Pharmacogenetics of Opioids
Andrew A Somogyi, Daniel T Barratt and Janet K Coller
Clin Pharmacol Ther 81: 429-444; doi:10.1038/sj.clpt.6100095
Public Policy
Tackling Corruption in the Pharmaceutical Systems Worldwide with Courage and Conviction
J C Cohen, M Mrazek and L Hawkins
Clin Pharmacol Ther 81: 445-449; advance online publication, January 24, 2007; doi:10.1038/sj.clpt.6100074
Planning for a National Effort to Enable and Accelerate Discoveries in Pharmacogenetics: The NIH Pharmacogenetics Research Network
R M Long
Clin Pharmacol Ther 81: 450-454; doi:10.1038/sj.clpt.6100099
Education
Biomedical Communications: Collaborative Research in Scientific Visualization, Online Learning, and Knowledge Translation
L Wilson-Pauwels, J Bajcar, N Woolridge and J Jenkinson
Clin Pharmacol Ther 81: 455-459; advance online publication, January 18, 2007; doi:10.1038/sj.clpt.6100060
