TABLE OF CONTENTS
Volume 80, Issue 1 (July 2006)
Pharmacogenetics and Genomics |
Pharmacokinetics and Drug Disposition |
Pharmacodynamics and Drug Action |
Letter to the Editor |
Guest Reviewers |
Books received |
Notes of the American Society for Clinical Pharmacology and Therapeutics
Commentaries
Improving how we evaluate the toxicity of approved drugs
Marcus M Reidenberg MD, FACP
Clin Pharmacol Ther 80: 1-6; doi:10.1016/j.clpt.2006.03.006
Genetic determinants of dose and clinical outcomes in patients receiving oral anticoagulants
Ute I Schwarz MD and C Michael Stein MD
Clin Pharmacol Ther 80: 7-12; doi:10.1016/j.clpt.2006.04.008
Pharmacogenetics and Genomics
VKORC1 and CYP2C9 genotypes and acenocoumarol anticoagulation status: Interaction between both genotypes affects overanticoagulation
Tom Schalekamp PharmD, Bjorn P Brassé PharmD, Janine F M Roijers MSc, Youssef Chahid BSc, Johanna H H van Geest-Daalderop MD, Hanneke de Vries-Goldschmeding MD, Eduard M van Wijk PhD, Antoine C G Egberts PharmD, PhD and Anthonius de Boer MD, PhD
Clin Pharmacol Ther 80: 13-22; doi:10.1016/j.clpt.2006.04.006
1-Adrenergic receptor polymorphisms influence the response to metoprolol monotherapy in patients with essential hypertension
Jie Liu MD, PhD, Zhao-Qian Liu MD, PhD, Bang-Ning Yu MD, PhD, Fang-Hua Xu MD, Wei Mo MD, Gan Zhou MD, Ying-Zi Liu MD, Qing Li MD and Hong-Hao Zhou MD
Clin Pharmacol Ther 80: 23-32; doi:10.1016/j.clpt.2006.03.004
Genetic polymorphism of cytochrome P450 2C19 in Mexican Americans: A cross-ethnic comparative study
Huai-Rong Luo PhD, Russell E Poland PhD, Keh-Ming Lin MD, MPH and Yu-Jui Yvonne Wan PhD
Clin Pharmacol Ther 80: 33-40; doi:10.1016/j.clpt.2006.03.003
Influences of proinflammatory and anti-inflammatory cytokine polymorphisms on eradication rates of clarithromycin-sensitive strains of Helicobacter pylori by triple therapy
Mitsushige Sugimoto MD, PhD, Takahisa Furuta MD, PhD, Naohito Shirai MD, PhD, Mutsuhiro Ikuma MD, PhD, Akira Hishida MD, PhD and Takashi Ishizaki MD, PhD
Clin Pharmacol Ther 80: 41-50; doi:10.1016/j.clpt.2006.03.007
CYP3A5*3 influences sirolimus oral clearance in de novo and stable renal transplant recipients
Yannick Le Meur MD, PhD, Nassim Djebli PharmD, Jean-Christophe Szelag MD, Guillaume Hoizey PharmD, Olivier Toupance MD, Jean Philippe Rérolle MD and Pierre Marquet MD, PhD
Clin Pharmacol Ther 80: 51-60; doi:10.1016/j.clpt.2006.03.012
Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implication for optimization of breast cancer treatment
Silvana Borges MD, Zeruesenay Desta PhD, Lang Li PhD, Todd C Skaar PhD, Bryan A Ward BSc, Anne Nguyen BSc, Yan Jin MD, Anna Maria Storniolo MD, D Michele Nikoloff PhD, Lin Wu PhD, Grant Hillman MSc, Daniel F Hayes MD, Vered Stearns MD and David A Flockhart MD, PhD
Clin Pharmacol Ther 80: 61-74; doi:10.1016/j.clpt.2006.03.013
Pharmacokinetics and Drug Disposition
Cytochrome P450 2B6 activity as measured by bupropion hydroxylation: Effect of induction by rifampin and ethnicity
Katarzyna K Loboz BSc(Hons), Annette S Gross PhD, Kenneth M Williams PhD, Winston S Liauw MBBS, Richard O Day MD, Julia K Blievernicht Dipl Biol, Ulrich M Zanger PhD and Andrew J McLachlan PhD
Clin Pharmacol Ther 80: 75-84; doi:10.1016/j.clpt.2006.03.010
Pharmacodynamics and Drug Action
Acute effects of sumatriptan on aortic blood pressure, stiffness, and pressure waveform
Floris H M Vanmolkot MD and Jan N J M de Hoon MD, PhD
Clin Pharmacol Ther 80: 85-94; doi:10.1016/j.clpt.2006.03.011
Letter to the Editor
Misestimating the role of an active metabolite when modeling the effects after administration of the parent compound only
Jörn Lötsch MD and Gerd Geisslinger MD, PhD
Clin Pharmacol Ther 80: 95-97; doi:10.1016/j.clpt.2006.04.005
Guest Reviewers
Guest reviewers 2005
Clin Pharmacol Ther 80: 98-101; doi:10.1016/j.clpt.2006.04.003
Books received
Books received
Clin Pharmacol Ther 80: 102-103; doi:10.1016/j.clpt.2006.04.009
