TABLE OF CONTENTS

Volume 79, Issue 5 (May 2006)

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Commentaries

Clinical Pharmacology & Therapeutics

C. Michael Stein MD

Clin Pharmacol Ther 79: 401-403; doi:10.1016/j.clpt.2006.03.009

Toward individualized analgesic therapy: Functional cyclooxygenase 1 and 2 haplotypes

Marc K. Halushka MD, PhD and Perry V. Halushka PhD, MD

Clin Pharmacol Ther 79: 404-406; doi:10.1016/j.clpt.2006.02.005

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Pharmacogenetic and genomics

Genetically mediated interindividual variation in analgesic responses to cyclooxygenase inhibitory drugs

Yun-Sil Lee DDS, MS, Hyungsuk Kim DDS, PhD, Tian-Xia Wu PhD, Xiao-Min Wang MD, PhD and Raymond A. Dionne DDS, PhD

Clin Pharmacol Ther 79: 407-418; doi:10.1016/j.clpt.2006.01.013

Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid-lowering efficacy of multiple-dose pravastatin

Michael Igel MD, Katja A. Arnold PhD, Mikko Niemi MD, Ute Hofmann PhD, Matthias Schwab MD, Dieter Lütjohann PhD, Klaus von Bergmann MD, Michel Eichelbaum MD and Kari T. Kivistö MD

Clin Pharmacol Ther 79: 419-426; advance online publication, April 11, 2006; doi:10.1016/j.clpt.2006.01.010

Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril

Kazuya Maeda MS, Ichiro Ieiri PhD, Kuninobu Yasuda MD, Akiharu Fujino PhD, Hiroaki Fujiwara PhD, Kenji Otsubo PhD, Masaru Hirano MS, Takao Watanabe MS, Yoshiaki Kitamura MS, Hiroyuki Kusuhara PhD and Yuichi Sugiyama PhD

Clin Pharmacol Ther 79: 427-439; advance online publication, April 11, 2006; doi:10.1016/j.clpt.2006.01.011

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Pharmacokinetics and drug disposition

Erythromycin breath test results in elderly, very elderly, and frail elderly persons

Janice B. Schwartz MD

Clin Pharmacol Ther 79: 440-448; advance online publication, April 11, 2006; doi:10.1016/j.clpt.2006.01.006

Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4–dependent pharmacokinetics in humans

Laurent Becquemont MD, PhD, Hartmut Glaeser PhD, Siegfried Drescher MD, Monika Hitzl PhD, Nicolas Simon MD, PhD, Thomas E. Murdter PhD, Georg Heinkele BSc, Ute Hofmann PhD, Christian Schaefer MD, Oliver Burk PhD, Céline Verstuyft PharmD, PhD, Michel Eichelbaum MD and Martin F. Fromm MD

Clin Pharmacol Ther 79: 449-460; advance online publication, April 11, 2006; doi:10.1016/j.clpt.2006.01.005

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites

Bojan Lalovic PhD, Evan Kharasch MD, PhD, Christine Hoffer BS, Linda Risler BS, Lee-Yuan Liu-Chen PhD and Danny D. Shen PhD

Clin Pharmacol Ther 79: 461-479; doi:10.1016/j.clpt.2006.01.009

Female sex and oral contraceptive use accelerate nicotine metabolism

Neal L. Benowitz MD, Christina N. Lessov-Schlaggar PhD, Gary E. Swan PhD and Peyton Jacob III PhD

Clin Pharmacol Ther 79: 480-488; doi:10.1016/j.clpt.2006.01.008

Liver dysfunction markedly decreases the inhibition of cytochrome P450 1A2–mediated theophylline metabolism by fluvoxamine

Rocco Orlando MD, Roberto Padrini MD, Mauro Perazzi PharmD, Sara De Martin PhD, Pierpaolo Piccoli PhD and Pietro Palatini PhD

Clin Pharmacol Ther 79: 489-499; doi:10.1016/j.clpt.2006.01.012

Influence of sibutramine treatment on sympathetic vasomotor tone in obese subjects

Karsten Heusser MD, Jens Tank MD, Andre Diedrich MD, Stefan Engeli MD, Susanne Klaua MD, Nadine Krüger, Anke Strauss RN, Gritt Stoffels RN, Friedrich C. Luft MD and Jens Jordan MD

Clin Pharmacol Ther 79: 500-508; doi:10.1016/j.clpt.2006.02.002

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Corrections

Corrections FREE

Clin Pharmacol Ther 79: 508; doi:10.1016/j.clpt.2006.03.005

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Letter to the Editor

Effect of CYP3A5*3 on carbamazepine pharmacokinetics in Japanese patients with epilepsy

Takayuki Seo MS, Naoyuki Nakada MS, Nao Ueda MS, Takashi Hagiwara MS, Nami Hashimoto MS, Kazuko Nakagawa MD, PhD and Takateru Ishitsu MD

Clin Pharmacol Ther 79: 509-510; doi:10.1016/j.clpt.2006.02.009

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Corrections

Correction FREE

Clin Pharmacol Ther 79: 510; doi:10.1016/j.clpt.2006.04.001

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