TABLE OF CONTENTS
Volume 77, Issue 6 (June 2005)
Pharmacogenetics and Genomics |
Pharmacokinetics and Drug Disposition |
Pharmacodynamics and Drug Action |
Clinical Pharmacology Grand Round |
Letters to the Editor |
Editorials |
Author Index
Commentary
CP&T Articles in Press will be Available Online
C. Michael Stein MD
Clin Pharmacol Ther 77: 457; doi:10.1016/j.clpt.2005.05.001
Pharmacogenetics and Genomics
Tramadol as a New Probe for Cytochrome P450 2D6 Phenotyping: A Population Study
Rasmus Steen Pedersen MSc, Per Damkier MD, PhD and Kim Brosen MD, DMSc
Clin Pharmacol Ther 77: 458-467; doi:10.1016/j.clpt.2005.01.014
Polymorphic Organic Anion Transporting Polypeptide 1B1 is a Major Determinant of Repaglinide Pharmacokinetics
Mikko Niemi MD, Janne T. Backman MD, Lauri I. Kajosaari MB, Julian B. Leathart MPhil, Mikko Neuvonen MSc, Ann K. Daly PhD, Michel Eichelbaum MD, Kari T. Kivistö MD and Pertti J. Neuvonen MD
Clin Pharmacol Ther 77: 468-478; doi:10.1016/j.clpt.2005.01.018
Allelic Variants of Cytochrome P450 2C9 Modify the Interaction Between Nonsteroidal Anti-inflammatory Drugs and Coumarin Anticoagulants
Loes E. Visser PharmD, PhD, Ron H. N. van Schaik PhD, Martin van Vliet, Paul H. Trienekens MSc, Peter A. G. M. De Smet PharmD, PhD, Arnold G. Vulto PharmD, PhD, Albert Hofman MD, PhD, Cornelia M. van Duijn PhD and Bruno H. Ch. Stricker MB, PhD
Clin Pharmacol Ther 77: 479-485; doi:10.1016/j.clpt.2005.02.009
Effect of the UGT2B15 Genotype on the Pharmacokinetics, Pharmacodynamics, and Drug Interactions of Intravenous Lorazepam in Healthy Volunteers
Jae-Yong Chung MD, Joo-Youn Cho PhD, Kyung-Sang Yu MD, PhD, Jung-Ryul Kim MD, Hye-Ryung Jung MS, Kyoung-Soo Lim MD, In-Jin Jang MD, PhD and Sang-Goo Shin MD, PhD
Clin Pharmacol Ther 77: 486-494; doi:10.1016/j.clpt.2005.02.006
Insulin-mediated Venodilation is Impaired in Young, Healthy Carriers of the 825T Allele of the G-protein 
3 Subunit Gene (GNB3)
Anna Mitchell MD, Mutlu Pace, Jens Nürnberger MD, René R. Wenzel MD, Winfried Siffert MD, Thomas Philipp MD and Rafael F. Schäfers MD
Clin Pharmacol Ther 77: 495-502; doi:10.1016/j.clpt.2005.03.002
Pharmacokinetics and Drug Disposition
Imaging P-glycoprotein Transport Activity at the Human Blood-brain Barrier with Positron Emission Tomography
Lucy Sasongko PhD, Jeanne M. Link PhD, Mark Muzi MS, David A. Mankoff MD, PhD, Xiaodong Yang PhD, Ann C. Collier MD, Steven C. Shoner PhD and Jashvant D. Unadkat PhD
Clin Pharmacol Ther 77: 503-514; doi:10.1016/j.clpt.2005.01.022
Population Pharmacokinetics and Exposure-response Relationship of Enfuvirtide in Treatment-experienced Human Immunodeficiency Virus Type 1—infected Patients
Diane R. Mould PhD, Xiaoping Zhang PhD, Keith Nieforth PharmD, Miklos Salgo MD, PhD, Neil Buss PhD and Indravadan H. Patel PhD
Clin Pharmacol Ther 77: 515-528; doi:10.1016/j.clpt.2005.02.005
Pharmacokinetics of Levetiracetam in Patients with Moderate to Severe Liver Cirrhosis (Child-Pugh Classes A, B, and C): Characterization by Dynamic Liver Function Tests
Jürgen Brockmöller MD, Torben Thomsen MD, Marcus Wittstock PhD, René Coupez, Herbert Lochs MD and Ivar Roots MD
Clin Pharmacol Ther 77: 529-541; doi:10.1016/j.clpt.2005.02.003
Dosing Strategy in Patients with Renal Failure Receiving Enoxaparin for the Treatment of non-ST-segment Elevation Acute Coronary Syndrome
Jean-Sébastien Hulot MD, Gilles Montalescot MD, PhD, Philippe Lechat MD, PhD, Jean-Philippe Collet MD, PhD, Annick Ankri MD and Saïk Urien MD, PhD
Clin Pharmacol Ther 77: 542-552; doi:10.1016/j.clpt.2005.02.012
Effect of Clopidogrel and Ticlopidine on Cytochrome P450 2B6 Activity as Measured by Bupropion Hydroxylation
Miia Turpeinen MD, Ari Tolonen PhD, Jouko Uusitalo MSc, Jorma Jalonen PhD, Olavi Pelkonen MD, PhD and Kari Laine MD, PhD
Clin Pharmacol Ther 77: 553-559; doi:10.1016/j.clpt.2005.02.010
Pharmacodynamics and Drug Action
Short-term Metabolic and Hemodynamic Effects of Ephedra and Guarana Combinations
Christine A. Haller MD, Peyton Jacob III PhD and Neal L. Benowitz MD
Clin Pharmacol Ther 77: 560-571; doi:10.1016/j.clpt.2005.01.023
A Pharmacokinetic-pharmacodynamic Model for the Quantitative Prediction of Dofetilide Clinical QT Prolongation from Human Ether-a-go-go-related Gene Current Inhibition Data
Daniël M. Jonker PhD, Leslie A. Kenna PhD, Derek Leishman PhD, Rob Wallis PhD, Peter A. Milligan PhD and E. Niclas Jonsson PhD
Clin Pharmacol Ther 77: 572-582; doi:10.1016/j.clpt.2005.02.004
Clinical Pharmacology Grand Round
The Use of Tegaserod in Critically ill Patients with Impaired Gastric Motility
Hoan Linh Banh PharmD, Charles MacLean BSc Pharm, Trevor Topp MD and Richard Hall MD
Clin Pharmacol Ther 77: 583-586; doi:10.1016/j.clpt.2005.02.002
Letters to the Editor
Detection of CYP2C9*5 in a White Brazilian Subject
Guilherme Suarez-Kurtz MD, DoctMed, Rosane Vianna-Jorge PharmD, PhD, Jamila A. Perini PharmD and Sergio D.J. Pena MD, PhD
Clin Pharmacol Ther 77: 587-588; doi:10.1016/j.clpt.2005.02.011
Editorials
Copyright Page for Index
Clin Pharmacol Ther 77: 590; doi:10.1016/S0009-9236(05)00227-4
