TABLE OF CONTENTS

Volume 71, Issue 1 (January 2002)

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Commentaries

Thoughts from the Editor FREE

Marcus M. Reidenberg MD

Clin Pharmacol Ther 71: 1-2; doi:10.1067/mcp.2002.121968

Centers for Education and Research on Therapeutics report: Survey of medication errors education during undergraduate and graduate medical education in the United States  FREE

Curtis J. Rosebraugh MD, MPH, Peter K. Honig MD, MPH, Sally Usdin Yasuda MS, PharmD, John C. Pezzullo PhD and Raymond L. Woosley MD, PhD

Clin Pharmacol Ther 71: 4-10; doi:10.1067/mcp.2002.120676

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Pharmacokinetics and Drug Disposition

Fruit juices inhibit organic anion transporting polypeptide–mediated drug uptake to decrease the oral availability of fexofenadine  FREE

George K. Dresser MD, David G. Bailey PhD, Brenda F. Leake BSc, Ute I. Schwarz MD, Paul A. Dawson PhD, David J. Freeman PhD and Richard B. Kim MD

Clin Pharmacol Ther 71: 11-20; doi:10.1067/mcp.2002.121152

Effects of grapefruit juice on the pharmacokinetics of sildenafil FREE

Alexander Jetter MD, Martina Kinzig-Schippers PhD, Monika Walchner-Bonjean MD, Ursula Hering MD, Jürgen Bulitta BSc, Philipp Schreiner BSc, Fritz Sörgel PhD, BSc and Uwe Fuhr MD

Clin Pharmacol Ther 71: 21-29; doi:10.1067/mcp.2002.121236

The effects of probenecid on the disposition of risperidone and olanzapine in healthy volunteers FREE

John S. Markowitz PharmD, C. Lindsay DeVane PharmD, Heidi L. Liston PharmD, David W. Boulton PhD and S. Craig Risch MD

Clin Pharmacol Ther 71: 30-38; doi:10.1067/mcp.2002.119815

Pharmacokinetics of betamethasone in twin and singleton pregnancy  FREE

Praveen Ballabh MD, E. S. Lo PhD, J. Kumari MD, T. B. Cooper MA, I. Zervoudakis MD, P. A. M. Auld MD and A. N. Krauss MD

Clin Pharmacol Ther 71: 39-45; doi:10.1067/mcp.2002.120250

Effect of modafinil on the pharmacokinetics of ethinyl estradiol and triazolam in healthy volunteers  FREE

Philmore Robertson Jr PhD, Edward T. Hellriegel PhD, Sanjay Arora PhD and Michael Nelson BA

Clin Pharmacol Ther 71: 46-56; doi:10.1067/mcp.2002.121217

The influence of efavirenz on the pharmacokinetics of a twice-daily combination of indinavir and low-dose ritonavir in healthy Volunteers  FREE

Rob E. Aarnoutse PharmD, Karin J. T. Grintjes, Denise S. C. Telgt MD, Michael Stek Jr MD, Patricia W. H. Hugen PharmD, PhD, Peter Reiss MD, PhD, Peter P. Koopmans MD, PhD, Yechiel A. Hekster PharmD, PhD and David M. Burger PharmD, PhD

Clin Pharmacol Ther 71: 57-67; doi:10.1067/mcp.2002.121424

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Pharmacodynamics and Drug Action

Comparative angiotensin II receptor blockade in healthy volunteers: The importance of dosing  FREE

Marc P. Maillard PhD, Grégoire Würzner MD, Jürg Nussberger MD, Catherine Centeno, Michel Burnier MD and Hans R. Brunner MD

Clin Pharmacol Ther 71: 68-76; doi:10.1067/mcp.2002.121425

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Pharmacogenetics and Genomics

The African-specific CYP2D6*17 allele encodes an enzyme with changed substrate specificity  FREE

Agneta Wennerholm MScPharm, Collet Dandara BSc, Jane Sayi MD, PhD, Jan-Olov Svensson Eng, Yakoub Aden Abdi MD, PhD, Magnus Ingelman-Sundberg PhD, Leif Bertilsson PhD, Julia Hasler PhD and Lars L. Gustafsson MD, PhD

Clin Pharmacol Ther 71: 77-88; doi:10.1067/mcp.2002.120239

Pharmacokinetics of losartan and its metabolite E-3174 in relation to the CYP2C9 genotype  FREE

Ümit Yasar MD, Cecilia Forslund-Bergengren MD, Gunnel Tybring PhD, Pedro Dorado, Adrián LLerena MD, PhD, Folke Sjöqvist MD, PhD, Erik Eliasson MD, PhD and Marja-Liisa Dahl MD, PhD

Clin Pharmacol Ther 71: 89-98; doi:10.1067/mcp.2002.121216

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Pharmacoepidemiology and Drug Utilization

Use of a spontaneous adverse drug events database for identification of unanticipated drug benefits FREE

Allen Brinker MD and Julie Beitz MD

Clin Pharmacol Ther 71: 99-102; doi:10.1067/mcp.2002.120677

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