TABLE OF CONTENTS

Volume 69, Issue 6 (June 2001)

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Commentaries

Clinical pharmacology: Niche or panorama? And does it matter? FREE

June W. Reidenberg MA

Clin Pharmacol Ther 69: 385-386; doi:10.1067/mcp.2001.116329

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Commentary

Integration of pharmacokinetic and pharmacodynamic studies in the discovery, development, and review of protein therapeutic agents: A conference report  FREE

Gerald R. Galluppi PhD, Mark C. Rogge PhD, Lorin K. Roskos PhD, Lawrence J. Lesko PhD, Martin D. Green PhD, David W. Feigal Jr MD and Carl C. Peck MD

Clin Pharmacol Ther 69: 387-399; doi:10.1067/mcp.2001.115455

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Pharmacokinetics and Drug Disposition

Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide  FREE

Mikko Niemi MD, Janne T. Backman MD, Mikko Neuvonen MSc, Pertti J. Neuvonen MD and Kari T. Kivistö MD

Clin Pharmacol Ther 69: 400-406; doi:10.1067/mcp.2001.115822

Population pharmacokinetic analysis of pegylated interferon alfa-2b and interferon alfa-2b in patients with chronic hepatitis C  FREE

J. Frank Jen PhD, Paul Glue MD, PhD, Farkad Ezzet PhD, Carol Chung PhD, Samir K. Gupta PhD, Sheila Jacobs PhD and Gerald Hajian PhD

Clin Pharmacol Ther 69: 407-421; doi:10.1067/mcp.2001.115872

Removal of digoxin by column for specific adsorption of beta2-microglobulin: A potential use for digoxin intoxication  FREE

Shuichi Tsuruoka, Eiichi Osono, Kenta Nishiki, Atsuhiro Kawaguchi, Tatsuhiko Arai, Sigeo Furuyoshi, Tetsuo Saito, Satoru Takata, Koichi Sugimoto, Satoshi Kurihara and Akio Fujimura

Clin Pharmacol Ther 69: 422-430; doi:10.1067/mcp.2001.116061

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Pharmacodynamics and Drug Action

The sugar absorption test in the evaluation of the gastrointestinal intolerance to bisphosphonates: Studies with oral pamidronate FREE

Irene M. Twiss MSc, Jacobus Burggraaf MD, PhD, Rick C. Schoemaker PhD, Ruurd M. van Elburg MD, PhD, Jan den Hartigh PhD, A. F. Cohen and Pieter Vermeij PhD

Clin Pharmacol Ther 69: 431-437; doi:10.1067/mcp.2001.115724

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Clinical Trial

Bupropion SR as an aid to smoking cessation in smokers treated previously with bupropion: A randomized placebo-controlled study  FREE

David H. Gonzales PhD, Mitchell A. Nides PhD, Linda H. Ferry MD, Robert P. Kustra PharmD, Brenda D. Jamerson PharmD, Nathan Segall MD, Luis A. Herrero MD, Alok Krishen MS, Addison Sweeney BA, Kathleen Buaron BSN and Alan Metz MD

Clin Pharmacol Ther 69: 438-444; doi:10.1067/mcp.2001.115750

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Pharmacoepidemiology and Drug Utilization

Comparison of patient questionnaires, medical records, and plasma assays in assessing exposure to benzodiazepines in elderly subjects  FREE

Nicholas Moore MD, PhD, Corinne Pierfitte MD, Fabienne Pehourcq PharmD, PhD, Rajaa Lagnaoui PharmD, MPH and Bernard Bégaud MD, PhD

Clin Pharmacol Ther 69: 445-450; doi:10.1067/mcp.2001.116147

Drug interactions as a cause of overanticoagulation on phenprocoumon or acenocoumarol predominantly concern antibacterial drugs  FREE

Fernie J. A. Penning-van Beest MSc, Erik van Meegen MD, Frits R. Rosendaal MD, PhD and Bruno H. Stricker MD, PhD

Clin Pharmacol Ther 69: 451-457; doi:10.1067/mcp.2001.115723

Incidence of serious adverse drug reactions in general practice: A prospective study FREE

Caroline Lacoste-Roussillon MD, MSc, Pierre Pouyanne MD, MSc, Françoise Haramburu MD, MSc, Ghada Miremont MD, MSc and Bernard Bégaud MD, PhD

Clin Pharmacol Ther 69: 458-462; doi:10.1067/mcp.2001.116145

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