TABLE OF CONTENTS
Volume 68, Issue 4 (October 2000)
Pharmacokinetics and Drug Disposition
Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: A new type of drug/drug interaction
Kristin Westphal MD, Anita Weinbrenner MD, Michael Zschiesche PhD, Gerd Franke PhD, Manfred Knoke MD, Reinhard Oertel PhD, Peter Fritz MD, Oliver von Richter PhD, Rolf Warzok MD, Thomas Hachenberg MD, Hans-Martin Kauffmann MD, Dieter Schrenk MD, Bernd Terhaag MD, Heyo K. Kroemer PhD and Werner Siegmund MD
Clin Pharmacol Ther 68: 345-355; doi:10.1067/mcp.2000.109797
In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone
Jeannine S. McCune PharmD, Roy L. Hawke PhD, Edward L. LeCluyse PhD, Heidi H. Gillenwater MD, Geraldine Hamilton PhD, James Ritchie PhD and Celeste Lindley PharmD, MS
Clin Pharmacol Ther 68: 356-366; doi:10.1067/mcp.2000.110215
Steady-state pharmacokinetics of indinavir in cerebrospinal fluid and plasma among adults with human immunodeficiency virus type 1 infection
David W. Haas MD, Julie Stone PhD, Lisa A. Clough MD, Benjamin Johnson MD, Paul Spearman MD, Victoria L. Harris EdD, Janet Nicotera BA, Regina H. Johnson BA, Stephen Raffanti MD, Ling Zhong PhD, Paul Bergqwist BS, Steven Chamberlin BS, Vicki Hoagland MS and William D. Ju MD
Clin Pharmacol Ther 68: 367-374; doi:10.1067/mcp.2000.109391
Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail"
Daniel S. Streetman PharmD, Jeffrey F. Bleakley MD, Jooran S. Kim PharmD, Anne N. Nafziger MD, MHS, J. Steven Leeder PharmD, PhD, Andrea Gaedigk PhD, Russell Gotschall MS, Gregory L. Kearns PharmD and Joseph S. Bertino Jr PharmD
Clin Pharmacol Ther 68: 375-383; doi:10.1067/mcp.2000.109519
Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin
Jari J. Lilja MD, Kari T. Kivistö MD and Pertti J. Neuvonen MD
Clin Pharmacol Ther 68: 384-390; doi:10.1067/mcp.2000.110216
Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin
Arthur L. Mazzu PhD, Kenneth C. Lasseter MD, E. Cooper Shamblen BS, Vipin Agarwal PhD, John Lettieri PhD and Pavur Sundaresen MD, PhD
Clin Pharmacol Ther 68: 391-400; doi:10.1067/mcp.2000.110537
In vivo modulation of CYP enzymes by quinidine and rifampin
Robert A. Branch MD, Adedayo Adedoyin PhD, Reginald F. Frye PhD, John W. Wilson PhD and Marjorie Romkes PhD
Clin Pharmacol Ther 68: 401-411; doi:10.1067/mcp.2000.110561
The effect of hormone replacement therapy on CYP3A activity
J. Christopher Gorski PhD, Zaiqi Wang MD, Barbara D. Haehner-Daniels MD, Steven A. Wrighton PhD and Stephen D. Hall PhD
Clin Pharmacol Ther 68: 412-417; doi:10.1067/mcp.2000.110560
Pharmacodynamics and Drug Action
Vascular effects of 5-HT1B/1D-receptor agonists in patients with migraine headaches
Jan N. J. M. de Hoon MD, Jean M. Willigers BSc, Jaap Troost MD, Harry A. J. Struijker-Boudier PhD and Luc M. A. B. Van Bortel MD
Clin Pharmacol Ther 68: 418-426; doi:10.1067/mcp.2000.110502
Simvastatin, capillary permeability, and acetylcholine-mediated vasomotion in atherosclerotic, hypercholesterolemic men
Giulia Dell'Omo MD, Simona Bandinelli MD, Giuseppe Penno MD, Roberto Pedrinelli MD and Mario Mariani MD
Clin Pharmacol Ther 68: 427-434; doi:10.1067/mcp.2000.109787
Paroxetine decreases platelet serotonin storage and platelet function in human beings
Nicole Hergovich MD, Martin Aigner MD, Hans-Georg Eichler MD, MSc, Jesusa Entlicher RN, Christa Drucker MT and Bernd Jilma MD
Clin Pharmacol Ther 68: 435-442; doi:10.1067/mcp.2000.110456
Hypotensive effect of calcium channel blockers is parallel with carbonic anhydrase I inhibition
Ioan Puscas MD, Ludovic Gilau MD, Marcela Coltau PhD, Radu Pasca MD, Gabriela Domuta Dr, Michael Baican Dr, MD and Alex Hecht Dr, PhD
Clin Pharmacol Ther 68: 443-449; doi:10.1067/mcp.2000.110559
