TABLE OF CONTENTS
Volume 68, Issue 1 (July 2000)
Pharmacokinetics and Drug Disposition |
Pharmacodynamics and Drug Action |
Pharmacogenetics and Genomics |
Clinical Pharmacology Grand Rounds
Commentaries
Is it sex or is it gender? FREE
Jooran S. Kim PharmD and Anne N. Nafziger MD, MHS
Clin Pharmacol Ther 68: 1-3; doi:10.1067/mcp.2000.108356
Targeting oral anticoagulation FREE
Murray Weiner MD
Clin Pharmacol Ther 68: 4-5; doi:10.1067/mcp.2000.108197
Pharmacokinetics and Drug Disposition
Oral bioavailability of digoxin is enhanced by talinolol: Evidence for involvement of intestinal P-glycoprotein FREE
Kristin Westphal MD, Anita Weinbrenner MD, Thomas Giessmann MD, Marko Stuhr MD, Gerd Franke PhD, Michael Zschiesche PhD, Reinhard Oertel PhD, Bernd Terhaag MD, Heyo K. Kroemer PhD and Werner Siegmund MD
Clin Pharmacol Ther 68: 6-12; doi:10.1067/mcp.2000.107579
Reduction of the inhibitory effect of ketoconazole on budesonide pharmacokinetics by separation of their time of administration FREE
Janeric Seidegård PhD
Clin Pharmacol Ther 68: 13-17; doi:10.1067/mcp.2000.106895
Comparison of manual versus ambulatory blood pressure measurements with pharmacokinetic-pharmacodynamic modeling of antihypertensive compounds: Application to moxonidine FREE
Iñaki F. Trocóniz PhD, Dinesh P. de Alwis PhD, Christiane Tillmann BSc, Sophie Callies PharmD, Malcolm Mitchell MBBS and Hans G. Schaefer PhD
Clin Pharmacol Ther 68: 18-27; doi:10.1067/mcp.2000.106907
Grapefruit juice–felodipine interaction in the elderly FREE
George K. Dresser MD, David G. Bailey PhD and S. George Carruthers MD
Clin Pharmacol Ther 68: 28-34; doi:10.1067/mcp.2000.107524
Inhibition of cytochrome P450 2A6 increases nicotine's oral bioavailability and decreases smoking FREE
Edward M. Sellers MD, PhD, Howard L. Kaplan PhD and Rachel F. Tyndale PhD
Clin Pharmacol Ther 68: 35-43; doi:10.1067/mcp.2000.107651
Pharmacokinetic and pharmacodynamic interaction between mexiletine and propafenone in human beings FREE
Line Labbé MSc, Gilles O'Hara MD, Michel Lefebvre MSc, Étienne Lessard MSc, Marcel Gilbert MD, Adedayo Adedoyin PhD, Jean Champagne MD, Bettina Hamelin PharmD and Jacques Turgeon PhD
Clin Pharmacol Ther 68: 44-57; doi:10.1067/mcp.2000.108023
Nicotine-mecamylamine interactions FREE
Shoshana Zevin MD, Peyton Jacob III PhD and Neal L. Benowitz MD
Clin Pharmacol Ther 68: 58-66; doi:10.1067/mcp.2000.108066
Pharmacodynamics and Drug Action
Big endothelin-3 constricts forearm resistance vessels but not hand veins in humans FREE
Charles J. Ferro MD, MRCP, Fiona E. Strachan BN, RGN, Ewan Shepherd BSc, William G. Haynes MD, FRCP and David J. Webb MD, FRCP
Clin Pharmacol Ther 68: 67-74; doi:10.1067/mcp.2000.107523
A novel S-nitrosothiol (RIG200) causes prolonged relaxation in dorsal hand veins with damaged endothelium FREE
Naoki Sogo MSc, Ian B. Wilkinson MRCP, Helen MacCallum BN, Sohail Q. Khan, Fiona E. Strachan BN, David E. Newby MRCP, Ian L. Megson PhD and David J. Webb MD
Clin Pharmacol Ther 68: 75-81; doi:10.1067/mcp.2000.107049
Pharmacogenetics and Genomics
CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4*1B 5'-promoter region polymorphism FREE
Christoph Wandel MD, John S. Witte PhD, Jefferey M. Hall PhD, C. Michael Stein MD, Alastair J. J. Wood MD and Grant R. Wilkinson PhD
Clin Pharmacol Ther 68: 82-91; doi:10.1067/mcp.2000.108506
Clinical Pharmacology Grand Rounds
Quetiapine fumarate overdose: Clinical and pharmacokinetic lessons from extreme conditions FREE
P. Timothy Pollak MD, PhD and Kevin Zbuk MD
Clin Pharmacol Ther 68: 92-97; doi:10.1067/mcp.2000.107507
Effect of intestinal P-glycoprotein on daily tacrolimus trough level in a living-donor small bowel recipient FREE
Satohiro Masuda PhD, Shinji Uemoto MD, Tohru Hashida BS, Yukihiro Inomata MD, Koichi Tanaka MD and Ken-ichi Inui PhD
Clin Pharmacol Ther 68: 98-103; doi:10.1067/mcp.2000.107912
