TABLE OF CONTENTS

Volume 66, Issue 4 (October 1999)

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Commentaries

Omission of authors

Clin Pharmacol Ther 66: 333; doi:10.1053/cp.1999.v66.a101062b

The case of the forgotten author: A mystery to editors

June Reidenberg MA

Clin Pharmacol Ther 66: 334-335; doi:10.1053/cp.1999.v66.a101062

The Molecular Therapeutics Section of the American Society for Clinical Pharmacology and Therapeutics

Scott A. Waldman MD, PhD, FCP and Andre Terzic MD, PhD

Clin Pharmacol Ther 66: 336-337; doi:10.1053/cp.1999.v66.a100878

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Pharmacokinetics and Drug Disposition

Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)

Andreas Johne MD, Jürgen Brockmöller MD, Steffen Bauer PhD, Agathe Maurer MD, Matthias Langheinrich MD and Ivar Roots MD

Clin Pharmacol Ther 66: 338-345; doi:10.1053/cp.1999.v66.a101944

Development of in vivo bioequivalence methodology for dermatologic corticosteroids based on pharmacodynamic modeling

Gur Jai Pal Singh PhD, Wallace P. Adams PhD, Lawrence J. Lesko PhD, Vinod P. Shah PhD, Justina A. Molzon MS, JD, Roger L. Williams MD and Lynn K. Pershing PhD

Clin Pharmacol Ther 66: 346-357; doi:10.1053/cp.1999.v66.a101209

Grapefruit juice has minimal effects on plasma concentrations of lovastatin-derived 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors

John D. Rogers PhD, Jamie Zhao PhD, Lida Liu MS, Raju D. Amin BS, Kathleen D. Gagliano BS, MEd, Arturo G. Porras PhD, Robert A. Blum PharmD, Michael F. Wilson MD, Michael Stepanavage MS and Jose M. Vega MD

Clin Pharmacol Ther 66: 358-366; doi:10.1053/cp.1999.v66.a101208

Time course and extent of angiotensin II antagonism after irbesartan, losartan, and valsartan in humans assessed by angiotensin II dose response and radioligand receptor assay

Gustav G. Belz MD, PhD, Raunhild Butzer MD, Susan Kober PhD, Christian Mang MD and Ernst Mutschler MD, PhD

Clin Pharmacol Ther 66: 367-373; doi:10.1053/cp.1999.v66.a101162

Ketoconazole inhibits the clearance of the enantiomers of the antidepressant reboxetine in humans

Beth D. Herman BS, Joseph C. Fleishaker PhD and Mark T. Brown MD

Clin Pharmacol Ther 66: 374-379; doi:10.1053/cp.1999.v66.a101207

Pharmacokinetics and pharmacodynamics of dichloroacetate in patients with cirrhosis

Robert E. Shangraw MD, PhD and Dennis M. Fisher MD

Clin Pharmacol Ther 66: 380-390; doi:10.1053/cp.1999.v66.a101340

Longitudinal assessment of a P-glycoprotein–mediated drug interaction of valspodar on digoxin

John M. Kovarik PhD, Laurence Rigaudy PhD, Madeleine Guerret PhD, Christophe Gerbeau PhD and Karl-Ludwig Rost PhD

Clin Pharmacol Ther 66: 391-400; doi:10.1053/cp.1999.v66.a101462

Mibefradil but not isradipine substantially elevates the plasma concentrations of the CYP3A4 substrate triazolam

Janne T. Backman MD, Jun-Sheng Wang MD, Xia Wen MD, Kari T. Kivistö MD and Pertti J. Neuvonen MD

Clin Pharmacol Ther 66: 401-407; doi:10.1053/cp.1999.v66.a101461

The effect of grapefruit juice on the time-dependent decline of artemether plasma levels in healthy subjects

Michiel A. van Agtmael MD, Veenu Gupta BS, Chantal A. A van der Graaf BS and Chris J. van Boxtel MD, PhD

Clin Pharmacol Ther 66: 408-414; doi:10.1053/cp.1999.v66.a101946

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Pharmacodynamics and Drug Action

Effect of filgrastim treatment on inflammatory cytokines and lymphocyte functions

Thomas Hartung MD, PhD, Wolf-Dietrich Doecke MD, Daniela Bundschuh PhD, MaryAnn Foote PhD, Florian Gantner PhD, Corinna Hermann MS, Andre Lenz, Steven Milwee PhD, Bill Rich MS, Bernadett Simon MS, Hans-Dieter Volk MD, PhD, Sonja von Aulock and Albrecht Wendel PhD

Clin Pharmacol Ther 66: 415-424; doi:10.1053/cp.1999.v66.a101210

Meloxicam, 15 mg/day, spares platelet function in healthy volunteers

Arthur de Meijer MD, Hans Vollaard PhD, Menno de Metz PhD, Bert Verbruggen, Chris Thomas PhD and Irena Novakova MD, PhD

Clin Pharmacol Ther 66: 425-430; doi:10.1053/cp.1999.v66.a101063

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Pharmacogenetics and Genomics

Flavin monooxygenase 3 (FMO3) polymorphism in a white population: Allele frequencies, mutation linkage, and functional effects on clozapine and caffeine metabolism

Christoph Sachse PhD, Steffen Ruschen, Michael Dettling MD, Jürgen Schley DSc, Steffen Bauer PhD, Bruno Müller-Oerlinghausen MD, Ivar Roots MD and Jürgen Brockmöller MD

Clin Pharmacol Ther 66: 431-438; doi:10.1053/cp.1999.v66.a102203

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