TABLE OF CONTENTS
Volume 65, Issue 5 (May 1999)
Pharmacodynamics and Drug Action |
Pharmacogenetics and Genomics |
Notes of the American Society for Clinical Pharmacology and Therapeutics
Pharmacokinetics and Drug Disposition
Investigation of terbinafine as a CYP2D6 inhibitor in vivo
Susan M. Abdel-Rahman PharmD, R. Russell Gotschall MS, Ralph E. Kauffman MD, J. Steven Leeder PharmD, PhD and Gregory L. Kearns PharmD
Clin Pharmacol Ther 65: 465-472; doi:10.1016/S0009-9236(99)70065-2
Pharmacokinetics and pharmacodynamics of SB 209670, an endothelin receptor antagonist: Effects on the regulation of renal vascular tone
Martin I. Freed MD, Douglas E. Wilson PharmD, Kathleen A. Thompson PhD, Robert Z. Harris PhD, Bernard E. Ilson MD and Diane K. Jorkasky MD
Clin Pharmacol Ther 65: 473-482; doi:10.1016/S0009-9236(99)70066-4
Thalidomide does not alter estrogen-progesterone hormone single-dose pharmacokinetics
Michael R. Scheffler PhD, Wayne Colburn PhD, Karin A. Kook PhD and Steve D. Thomas PhD
Clin Pharmacol Ther 65: 483-490; doi:10.1016/S0009-9236(99)70067-6
Clinical pharmacokinetics of encapsulated oral 9-aminocamptothecin in plasma and saliva
Maja J.A. de Jonge MD, Jaap Verweij MD, PhD, Walter J. Loos BSc, Brian K. Dallaire PharmD and Alex Sparreboom PhD
Clin Pharmacol Ther 65: 491-499; doi:10.1016/S0009-9236(99)70068-8
Quinine disposition in globally malnourished children with cerebral malaria
Eric Pussard PhD, Hubert Barennes MD, Hamani Daouda PhD, Françoise Clavier BS, Abdoulaye Mahaman Sani MD, Martin Osse MD, Gérard Granic MD and Françoise Verdier PhD
Clin Pharmacol Ther 65: 500-510; doi:10.1016/S0009-9236(99)70069-X
Influence of arteriovenous sampling on remifentanil pharmacokinetics and pharmacodynamics
David J. Hermann PharmD, Talmage D. Egan MD and Keith T. Muir PhD
Clin Pharmacol Ther 65: 511-518; doi:10.1016/S0009-9236(99)70070-6
Pharmacodynamics and Drug Action
Impact of genetic polymorphisms of the 
2-adrenergic receptor on albuterol bronchodilator pharmacodynamics
John J. Lima PharmD, Donald B. Thomason PhD, Mohamad H.N. Mohamed PharmD, Louis V. Eberle MD, Timothy H. Self PharmD and Julie A. Johnson PharmD
Clin Pharmacol Ther 65: 519-525; doi:10.1016/S0009-9236(99)70071-8
The cytotoxicity of clozapine metabolites: Implications for predicting clozapine-induced agranulocytosis
Alice C. Tschen MSc, Michael J. Rieder MD, PhD, L. Kola Oyewumi MD and David J. Freeman PhD
Clin Pharmacol Ther 65: 526-532; doi:10.1016/S0009-9236(99)70072-X
Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state
Irmgard Tegeder MD, Jörn Lötsch MD, Sabine Krebs, Uta Muth-Selbach MD, Kay Brune MD and Gerd Geisslinger MD, PhD
Clin Pharmacol Ther 65: 533-544; doi:10.1016/S0009-9236(99)70073-1
G-Protein–coupled receptor kinase expression in hypertension
Robert Gros MSc, Christopher M. Tan BSc, Jozef Chorazyczewski MSc, David J. Kelvin PhD, Jeffrey L. Benovic PhD and Ross D. Feldman MD
Clin Pharmacol Ther 65: 545-551; doi:10.1016/S0009-9236(99)70074-3
Pharmacogenetics and Genomics
CYP2C19 genotype status and effect of omeprazole on intragastric pH in humans
Takahisa Furuta MD, Kyoichi Ohashi MD, Kazuhiro Kosuge PhD, Xue-Jun Zhao MD, Misako Takashima MD, Masahiko Kimura MD, Masahiko Nishimoto MD, Hiroyuki Hanai MD, Eizo Kaneko MD and Takashi Ishizaki MD
Clin Pharmacol Ther 65: 552-561; doi:10.1016/S0009-9236(99)70075-5
Relationship between acetylation polymorphism and risk of atopic diseases
Barbara Gawro
ska-Szklarz PhD, Teresa Luszawska-Kutrzeba MD, PhD, Gra
yna Czaja-Bulsa MD, PhD and Grzegorz Kurzawski PhD
Clin Pharmacol Ther 65: 562-569; doi:10.1016/S0009-9236(99)70076-7
Analysis of the CYP2D6 gene in relation to dextromethorphan O-demethylation capacity in a Japanese population
Tomonori Tateishi MD, Michihiro Chida PhD, Noritaka Ariyoshi PhD, Yoshihiro Mizorogi BS, Tetsuya Kamataki PhD and Shinichi Kobayashi MD
Clin Pharmacol Ther 65: 570-575; doi:10.1016/S0009-9236(99)70077-9
Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism
Lalitha Iyer PhD, Diana Hall BS, Soma Das PhD, Melissa A. Mortell BA, Jacqueline Ramírez MS, Sarang Kim MD, Anna Di Rienzo PhD and Mark J. Ratain MD
Clin Pharmacol Ther 65: 576-582; doi:10.1016/S0009-9236(99)70078-0
Notes of the American Society for Clinical Pharmacology and Therapeutics
Notes of the American Society for Clinical Pharmacology and Therapeutics
Judith K. Jones MD, PhD
Clin Pharmacol Ther 65: 586; doi:10.1016/S0009-9236(99)70079-2
