TABLE OF CONTENTS
Volume 65, Issue 3 (March 1999)
Pharmacokinetics and Drug Disposition |
Pharmacodynamics and Drug Action |
Clinical Trials and Therapeutics |
Clinical Pharmacology Rounds |
USAN Council
Note from the Editor
New headings for the Table of Contents
Marcus M. Reidenberg MD
Clin Pharmacol Ther 65: 235-236; doi:10.1016/S0009-9236(99)70101-3
Pharmacokinetics and Drug Disposition
6',7'-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein
David J. Edwards PharmD, Michael E. Fitzsimmons PhD, Erin G. Schuetz PhD, Kazuto Yasuda MS, Murray P. Ducharme PharmD, Lawrence H. Warbasse MD, Patrick M. Woster PhD, John D. Schuetz PhD and Paul Watkins MD
Clin Pharmacol Ther 65: 237-244; doi:10.1016/S0009-9236(99)70102-5
Tobramycin penetration into epithelial lining fluid of patients with pneumonia
Antonio J. Carcas PhD, José Luis García-Satué MD, Pedro Zapater PhD and Jesús Frías-Iniesta PhD
Clin Pharmacol Ther 65: 245-250; doi:10.1016/S0009-9236(99)70103-7
Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients
Wolfgang Mück PhD, Ingrid Mai MD, Lutz Fritsche MD, Klaus Ochmann MD, Gabriele Rohde PhD, Sigrun Unger MS, Andreas Johne MD, Steffen Bauer PhD, Klemens Budde MD, Ivar Roots MD, Hans-Hellmut Neumayer MD and Jochen Kuhlmann MD
Clin Pharmacol Ther 65: 251-261; doi:10.1016/S0009-9236(99)70104-9
Interaction of pefloxacin and enoxacin with the human cytochrome P450 enzyme CYP1A2
Martina Kinzig-Schippers PhD, Uwe Fuhr MD, Michael Zaigler MD, Jörg Dammeyer MD, Guido Rüsing MSc, Andreas Labedzki BSc, Jürgen Bulitta BSc and Fritz Sörgel BSc, PhD
Clin Pharmacol Ther 65: 262-274; doi:10.1016/S0009-9236(99)70105-0
Phenotypic-genotypic analysis of CYP2C19 in the Jewish Israeli population
Sigal Sviri MD, Shoshi Shpizen, Eran Leitersdorf MD, Micha Levy MD and Yoseph Caraco MD
Clin Pharmacol Ther 65: 275-282; doi:10.1016/S0009-9236(99)70106-2
Unexpected effect of verapamil on oral bioavailability of the 
-blocker talinolol in humans
Ute I. Schwarz MD, Thomas Gramatté MD, PhD, Jutta Krappweis MD, Annette Berndt MD, Reinhard Oertel PhD, Oliver von Richter PharmD and Wilhelm Kirch MD, PhD
Clin Pharmacol Ther 65: 283-290; doi:10.1016/S0009-9236(99)70107-4
Effects of the CYP2D6*10 allele on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese patients with schizophrenia
Kazuo Mihara MD, PhD, Akihito Suzuki MD, Tsuyoshi Kondo MD, PhD, Norio Yasui MD, PhD, Hanako Furukori MD, Udai Nagashima MD, Koichi Otani MD, PhD, Sunao Kaneko MD, PhD and Yoshimasa Inoue
Clin Pharmacol Ther 65: 291-294; doi:10.1016/S0009-9236(99)70108-6
Pharmacodynamics and Drug Action
Angiotensin-converting enzyme inhibition improves venous endothelial dysfunction in chronic smokers
Stephan Chalon MD, Heitor Moreno Jr MD, PhD, Brian B. Hoffman MD and Terrence F. Blaschke MD
Clin Pharmacol Ther 65: 295-303; doi:10.1016/S0009-9236(99)70109-8
Pharmacoimmunodynamic interactions of interleukin-10 and prednisone in healthy volunteers
Abhijit Chakraborty MS, Robert A. Blum PharmD, David L. Cutler MD and William J. Jusko PhD
Clin Pharmacol Ther 65: 304-318; doi:10.1016/S0009-9236(99)70110-4
Clinical Trials and Therapeutics
Angiotensin-converting enzyme inhibition facilitates alveolar-capillary gas transfer and improves ventilation-perfusion coupling in patients with left ventricular dysfunction
Marco Guazzi MD, Gloria Melzi MD, Gian Carlo Marenzi MD and Piergiuseppe Agostoni MD
Clin Pharmacol Ther 65: 319-327; doi:10.1016/S0009-9236(99)70111-6
Does short-term treatment with modafinil affect blood pressure in patients with obstructive sleep apnea?
Jörg Heitmann MD, Werner Cassel DiplPsych, Ludger Grote MD, Ulrich Bickel MD, PhD, Udo Hartlaub DiplBiol, Thomas Penzel PhD and Jörg Hermann Peter MD, PhD
Clin Pharmacol Ther 65: 328-335; doi:10.1016/S0009-9236(99)70112-8
Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model
Elliot W. Ehrich MD, Aimee Dallob MS, Inge De Lepeleire MS, Anne Van Hecken PhD, Denis Riendeau PhD, Weiying Yuan PhD, Arturo Porras PhD, Johanna Wittreich BS, James R. Seibold MD, Paul De Schepper MD, PhD, Donald R. Mehlisch MD, DDS and Barry J. Gertz MD, PhD
Clin Pharmacol Ther 65: 336-347; doi:10.1016/S0009-9236(99)70113-X
Clinical Pharmacology Rounds
Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174
Jacqueline B. McCrea PharmD, Alastair Cribb DVM, PhD, Tom Rushmore PhD, Barbara Osborne RN, Lisa Gillen MS, Man-Wai Lo PhD, Scott Waldman MD, PhD, Thorir Bjornsson MD, PhD, Stephen Spielberg MD, PhD and Michael R. Goldberg MD, PhD
Clin Pharmacol Ther 65: 348-352; doi:10.1016/S0009-9236(99)70114-1
