TABLE OF CONTENTS

Volume 64, Issue 6 (December 1998)

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Commentary

The effectiveness of antihistamines in reducing the severity of runny nose and sneezing: A meta-analysis

Ralph B. D'Agostino Sr PhD, Michael Weintraub MD, Heidy K. Russell PhD, Miganush Stepanians PhD, Ralph B. D'Agostino Jr PhD, Louis R. Cantilena Jr MD, PhD, James F. Graumlich MD, Sam Maldonado MD, Peter Honig MD and Charles Anello DSc

Clin Pharmacol Ther 64: 579-596; doi:10.1016/S0009-9236(98)90049-2

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Pharmacokinetics and Drug Disposition

Thalidomide does not alter the pharmacokinetics of ethinyl estradiol and norethindrone

Carol Braun Trapnell MD, Stephen R. Donahue MD, Jerry M. Collins PhD, David A. Flockhart MD, PhD, David Thacker BS and Darrell R. Abernethy MD, PhD

Clin Pharmacol Ther 64: 597-602; doi:10.1016/S0009-9236(98)90050-9

Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone

Tarja Heiskanen MD, Klaus T. Olkkola DMedSci and Eija Kalso DMedSci

Clin Pharmacol Ther 64: 603-611; doi:10.1016/S0009-9236(98)90051-0

Pharmacokinetics, pharmacodynamics, and tolerance of single- and multiple-dose fexofenadine hydrochloride in healthy male volunteers

Tanya Russell PhD, Maxine Stoltz PhD and Scott Weir PharmD, PhD

Clin Pharmacol Ther 64: 612-621; doi:10.1016/S0009-9236(98)90052-2

Population pharmacokinetic-pharmacodynamic modeling of moxonidine using 24-hour ambulatory blood pressure measurements

Georg Hempel PhD, Mats O. Karlsson PhD, Dinesh P. de Alwis PhD, Nathalie Toublanc PharmD, John McNay MD and Hans G. Schaefer PhD

Clin Pharmacol Ther 64: 622-635; doi:10.1016/S0009-9236(98)90053-4

A model for the turnover of dihydrotestosterone in the presence of the irreversible 5alpha-reductase inhibitors GI198745 and finasteride

Per Olsson Gisleskog MSc, David Hermann PhD, Margareta Hammarlund-Udenaes PhD and Mats O. Karlsson PhD

Clin Pharmacol Ther 64: 636-647; doi:10.1016/S0009-9236(98)90054-6

Tamoxifen and toremifene concentrations in plasma are greatly decreased by rifampin

Kari T. Kivistö MD, Kirsti Villikka MD, Leena Nyman MSc, Markku Anttila MSc and Pertti J. Neuvonen MD

Clin Pharmacol Ther 64: 648-654; doi:10.1016/S0009-9236(98)90055-8

Grapefruit juice substantially increases plasma concentrations of buspirone

Jari J. Lilja MD, Kari T. Kivistö MD, Janne T. Backman MD, Tommi S. Lamberg MD and Pertti J. Neuvonen MD

Clin Pharmacol Ther 64: 655-660; doi:10.1016/S0009-9236(98)90056-X

Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole

David J. Greenblatt, Lisa L. von Moltke, Jerold S. Harmatz, Polyxane Mertzanis, Jennifer A. Graf, Anna Liza B. Durol, Molly Counihan, Barbara Roth-Schechter and Richard I. Shader

Clin Pharmacol Ther 64: 661-671; doi:10.1016/S0009-9236(98)90057-1

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Clinical Trials and Therapeutics

The pharmacokinetic-pharmacodynamic relationship for mycophenolate mofetil in renal transplantation

Michael D. Hale PhD, Andrew J. Nicholls MD, Roy E.S. Bullingham MD, Ronald Hené MD, A. Hoitsma MD, Jean-Paul Squifflet MD, W. Weimar MD, Yves Vanrenterghem MD, Fokko J. Van de Woude MD and Gert A. Verpooten MD

Clin Pharmacol Ther 64: 672-683; doi:10.1016/S0009-9236(98)90058-3

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Pharmacoepidemiology and Drug Utilization

Benzodiazepine use and cognitive function among community-dwelling elderly

Joseph T. Hanlon PharmD, MS, Ronnie D. Horner PhD, Kenneth E. Schmader MD, Gerda G. Fillenbaum PhD, Ingrid K. Lewis PharmD, William E. Wall Jr BA, Lawrence R. Landerman PhD, Carl F. Pieper DrPH, Dan G. Blazer MD, PhD and Harvey Jay Cohen MD

Clin Pharmacol Ther 64: 684-692; doi:10.1016/S0009-9236(98)90059-5

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Notes of the American Society for Clinical Pharmacology and Therapeutics

A message from the president: The centennial ASCPT meeting—Come to San Antonio, March 18–20, 1999

Carl C. Peck MD , President

Clin Pharmacol Ther 64: 693-694; doi:10.1016/S0009-9236(98)90060-1

1999 ASCPT clinical pharmacology curriculum review course

Darrell R. Abernethy MD, PhD, Course Co-Director and Raymond L. Woosley MD, PhD, Course Co-Director

Clin Pharmacol Ther 64: 694; doi:10.1016/S0009-9236(98)90061-3

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USAN Council

List no. 411: New Names

Clin Pharmacol Ther 64: 695-696; doi:10.1016/S0009-9236(98)90062-5

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Author Index

Author and subject index for volume 64

Clin Pharmacol Ther 64: 699-714; doi:10.1016/S0009-9236(98)90063-7

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