TABLE OF CONTENTS
Volume 61, Issue 4 (April 1997)
Pharmacokinetics and Drug Disposition |
Pharmacodynamics and Drug Action |
Clinical Trials and Therapeutics |
Letters to the Editor |
Statement from the Editors |
Guest Reviewers |
USAN Council
Commentaries
Drug interactions with grapefruit: Whose responsibility is it to warn the public?
J. David Spence MD, FRCPC, FACP
Clin Pharmacol Ther 61: 395-400; doi:10.1016/S0009-9236(97)90189-2
Pharmacokinetics and Drug Disposition
Grapefruit juice—terfenadine single-dose interaction: Magnitude, mechanism, and relevance
Susan E. Rau MSc, John R. Bend PhD, J. Malcolm O. Arnold MD, Lan T. Tran BSc, J. David Spence MD and David G. Bailey PhD
Clin Pharmacol Ther 61: 401-409; doi:10.1016/S0009-9236(97)90190-9
Itraconazole greatly increases plasma concentrations and effects of felodipine
Kirsi-Maija Jalava MD, Klaus T. Olkkola MD, PhD and Pertti J. Neuvonen MD, PhD
Clin Pharmacol Ther 61: 410-415; doi:10.1016/S0009-9236(97)90191-0
Population pharmacokinetics of sirolimus in kidney transplant patients
Geraldine M. Ferron PharmD, Elena V. Mishina PhD, James J. Zimmerman PhD and William J. Jusko PhD
Clin Pharmacol Ther 61: 416-428; doi:10.1016/S0009-9236(97)90192-2
Quantitation of interference in digoxin immunoassay in renal, hepatic, and diabetic disease
Meir C. Tzou PhD, Richard H. Reuning PhD and Richard A. Sams PhD
Clin Pharmacol Ther 61: 429-441; doi:10.1016/S0009-9236(97)90193-4
Stereoselective pharmacokinetic analysis of valnoctamide in healthy subjects and in patients with epilepsy
Shimon Barel PhD, Boris Yagen PhD, Volker Schurig PhD, Stephan Soback DVM, PhD, Francesco Pisani MD, Emilio Perucca MD, PhD and Meir Bialer PhD, MBA
Clin Pharmacol Ther 61: 442-449; doi:10.1016/S0009-9236(97)90194-6
Lansoprazole pharmacokinetics in subjects with various degrees of kidney function
Michael D. Karol PhD, Joseph M. Machinist PhD and John M. Cavanaugh PhD, MD
Clin Pharmacol Ther 61: 450-458; doi:10.1016/S0009-9236(97)90195-8
Pharmacodynamics and Drug Action
Effect of codeine on gastrointestinal motility in relation to CYP2D6 phenotype
Gerd Mikus MD, Beate Trausch MD, Carsten Rodewald MD, Ute Hofmann PhD, Klaus Richter PhD, Thomas Gramatté MD and Michel Eichelbaum MD
Clin Pharmacol Ther 61: 459-466; doi:10.1016/S0009-9236(97)90196-X
Clinical Trials and Therapeutics
The safety and efficacy of oral methylnaltrexone in preventing morphine-induced delay in oral-cecal transit time
Chun-Su Yuan MD, PhD, Joseph F. Foss MD, Joachim Osinski MS, Alicia Toledano ScD, Michael F. Roizen MD and Jonathan Moss MD, PhD
Clin Pharmacol Ther 61: 467-475; doi:10.1016/S0009-9236(97)90197-1
Comparative sexual side effects of bupropion, fluoxetine, paroxetine, and sertraline
Jack G. Modell MD, Charles R. Katholi PhD, Judith D. Modell BA and R. Lawrence DePalma MD
Clin Pharmacol Ther 61: 478-487; doi:10.1016/S0009-9236(97)90198-3
Multicenter study on self-medication and self-prescription in six Latin American countries
Drug Utilization Research Group, Latin America Coordinating center and data analysis: Josep Ma Castel MD, Joan-Ramon Laporte MD, Valerio Reggi PhD, Participating centers:Jorge Aguirre MD, Perla Mordujovich de Buschiazzo MD, Helena Lutescia Coelho PharmD, Maria Do Carmo Dias Batista MD, Marisa Lima Carvalho MD, Roberto E. Righi PharmD, Juan Carlos Prieto MD, Jesualdo Fuentes MD, Albin Chaves MD, René Mendieta MD and Jaime Orozco MD
Clin Pharmacol Ther 61: 488-493; doi:10.1016/S0009-9236(97)90199-5
Letters to the Editor
Disclosure of analytical information in pharmacokinetic papers
Ira Weinryb PhD
Clin Pharmacol Ther 61: 494; doi:10.1016/S0009-9236(97)90200-9
Publication and proprietary information
James F. Burris MD
Clin Pharmacol Ther 61: 494-495; doi:10.1016/S0009-9236(97)90201-0
Publication and proprietary information
George Lunn PhD
Clin Pharmacol Ther 61: 495; doi:10.1016/S0009-9236(97)90202-2
Publishing Summary Basis of Approval
H. I. Silverman DSc
Clin Pharmacol Ther 61: 495-496; doi:10.1016/S0009-9236(97)90203-4
Note from the Editor
Marcus M. Reidenberg MD , Editor
Clin Pharmacol Ther 61: 496; doi:10.1016/S0009-9236(97)90205-8
Statement from the Editors
What should authors expect from the reviewers and the editors of Clinical Pharmacology & Therapeutics?
Marcus M. Reidenberg MD Editor
Clin Pharmacol Ther 61: 497-498; doi:10.1016/S0009-9236(97)90206-X
