TABLE OF CONTENTS

Volume 38, Issue 4 (October 1985)

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Commentary

The computerized on-line Medicaid pharmaceutical analysis and surveillance system: A new resource for postmarketing drug surveillance

Brian L Strom MD, MPH, Jeffrey L Carson MD, M Lee Morse PharmB and Aida A LeRoy PharmD Philadelphia, Pa., Camden, N.J., and Arlington, Va.

Clin Pharmacol Ther 38: 359-364; doi:10.1038/clpt.1985.188

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Original Articles

Morphine-induced skin wheals: A possible model for the study of histamine release

Roberto Saucedo MD and Sergio Erill MD Granada, Spain

Clin Pharmacol Ther 38: 365-370; doi:10.1038/clpt.1985.189

Interactions between ethanol and oral contraceptive steroids

Joy Hobbes MSc, John Boutagy PhD and Gillian M Shenfield DM St. Leonards, Australia

Clin Pharmacol Ther 38: 371-380; doi:10.1038/clpt.1985.190

The acute effects of acrivastine (BW825C), a new antihistamine, compared with triprolidine on measures of central nervous system performance and subjective effects

A F Cohen MD, M Hamilton PhD, R Philipson and A W Peck PhD Kent, United Kingdom

Clin Pharmacol Ther 38: 381-386; doi:10.1038/clpt.1985.191

Sulindac metabolism: The importance of an intact colon

H A Strong BSc, N J Warner, A G Renwick PhD and C F George MD Southampton, United Kingdom

Clin Pharmacol Ther 38: 387-393; doi:10.1038/clpt.1985.192

A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin

E Steiner MD, L Iselius MD, G Alván MD, J Lindsten MD and F Sjöqvist MD Stockholm, Sweden

Clin Pharmacol Ther 38: 394-401; doi:10.1038/clpt.1985.193

Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations

K Nakamura MD, F Goto MD, W A Ray PhD, C B McAllister MS, E Jacqz MD, G R Wilkinson PhD and R A Branch MD Nashville, Tenn., and Tsukuba, Japan

Clin Pharmacol Ther 38: 402-408; doi:10.1038/clpt.1985.194

Pharmacokinetics and beta-blocking effects of timolol in poor and extensive metabolizers of debrisoquin

John C McGourty MB, Joseph H Silas MD, Jude J Fleming PhD, Alan McBurney MPhil and John W Ward MB Merseyside and Leicester, United Kingdom

Clin Pharmacol Ther 38: 409-413; doi:10.1038/clpt.1985.195

Stereoselective mephobarbital hydroxylation cosegregates with mephenytoin hydroxylation

A Küpfer PhD and R A Branch MD Nashville, Tenn., and Bern, Switzerland

Clin Pharmacol Ther 38: 414-418; doi:10.1038/clpt.1985.196

Effects of long-term therapy with naltrexone on body weight in obesity

Richard L Atkinson MD, Lisa K Berke MSN, FNP, Charles R Drake MD, Mary Lynn Bibbs MSN, FNP, Frederick L Williams MD and Donald L Kaiser PhD Charlottesville, Va.

Clin Pharmacol Ther 38: 419-422; doi:10.1038/clpt.1985.197

Terazosin kinetics after oral and intravenous doses

Sean E Patterson PhD Abbott Park, Ill.

Clin Pharmacol Ther 38: 423-427; doi:10.1038/clpt.1985.198

Ventilatory effects of atenolol and bevantolol in asthma

Jan-Willem J Lammers MD, Hans T M Folgering MD and Cees L A van Herwaarden MD H. Landstichting, The Netherlands

Clin Pharmacol Ther 38: 428-433; doi:10.1038/clpt.1985.199

Antihypertensive and cardiovascular effects of nitrendipine: A controlled study vs. placebo

Liberato Aldo Ferrara MD, Maria Luisa Fasano MD, Giovanni de Simone MD, Stefano Soro MD and Renato Gagliardi BSc Naples, Italy

Clin Pharmacol Ther 38: 434-438; doi:10.1038/clpt.1985.200

Pefloxacin kinetics in cirrhosis

Gaby Danan MD, Guy Montay, Rober Cunci MD and Serge Erlinger MD Clichy and Alfortville, France

Clin Pharmacol Ther 38: 439-442; doi:10.1038/clpt.1985.201

Inhibition of prostaglandin synthesis by indomethacin interacts with the antihypertensive effect of atenolol

Pauli Ylitalo MD, Timo Pitkäjärvi MD, Maija-Liisa Pyykönen MD, Anna-Kaisa Nurmi MSc, Erkki Seppälä MD, MSc and Heikki Vapaatalo MD Tampere, Finland

Clin Pharmacol Ther 38: 443-449; doi:10.1038/clpt.1985.202

Transdermal nicotine reduces cigarette craving and nicotine preference

Jed E Rose PhD, Joseph E Herskovic PhD, Yvonne Trilling and Murray E Jarvik MD, PhD Los Angeles, Calif.

Clin Pharmacol Ther 38: 450-456; doi:10.1038/clpt.1985.203

Pharmacokinetics of high-dose pentobarbital in severe head trauma

Charles D Bayliff PharmD, Michael L Schwartz MD and Brian G Hardy PharmD Toronto, Ontario, Canada

Clin Pharmacol Ther 38: 457-461; doi:10.1038/clpt.1985.204

Pharmacokinetics of a new angiotensin I converting enzyme inhibitor (alacepril) after oral dosing in fasting or fed states

Kaoru Onoyama MD, Hideki Hirakata MD, Hiroshi Tsuruda MD, Nobuaki Ohchi MD, Suguru Tomooka MD, Kenichi Motomura MD, Teruo Omae MD, Kouji Hayashi PhD and Masatoshi Fujishima MD Fukuoka, Japan

Clin Pharmacol Ther 38: 462-468; doi:10.1038/clpt.1985.205

New insights into the pharmacokinetics of spironolactone

Hans W P M Overdiek PharmD, Walter A J J Hermens BS and Frans W H M Merkus PhD Sittard and Amsterdam, The Netherlands

Clin Pharmacol Ther 38: 469-474; doi:10.1038/clpt.1985.206

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Letters to the Editor

Concomitant food intake does enhance the bioavailability and effect of hydralazine

A Melander MD, H Liedholm MD and A McLean MD

Clin Pharmacol Ther 38: 475; doi:10.1038/clpt.1985.207

Reply

Alexander M M Shepherd MD, PhD and Thomas M Ludden PhD

Clin Pharmacol Ther 38: 475-476; doi:10.1038/clpt.1985.208

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List of Reviewers

List of reviewers

Clin Pharmacol Ther 38: 477; doi:10.1038/clpt.1985.209

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Notes of the American Society for Clinical Pharmacology and Therapeutics

Notes of the American Society for Clinical Pharmacology and Therapeutics

Clin Pharmacol Ther 38: 478; doi:10.1038/clpt.1985.210

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USAN Council

List No. 265

Clin Pharmacol Ther 38: 479-480; doi:10.1038/clpt.1985.211

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