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Synthesis

  • Protocol

    Use of Raman spectroscopy as a tool for in situ monitoring of microwave-promoted reactions

    Nicholas E Leadbeater & Jason R Schmink

    doi:10.1038/nprot.2007.453

    Nature Protocols 3; 1 - 7 (2008)

    Published online: 20 December 2007

    Abstract | Full Text | PDF (805K)

  • Protocol

    Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine

    Jacek Zielonka, Jeannette Vasquez-Vivar & Balaraman Kalyanaraman

    doi:10.1038/nprot.2007.473

    Nature Protocols 3; 8 - 21 (2008)

    Published online: 20 December 2007

    Abstract | Full Text | PDF (470K)

  • Protocol

    Pd-catalyzed Suzuki–Miyaura reactions of aryl halides using bulky biarylmonophosphine ligands

    Ryan A Altman & Stephen L Buchwald

    doi:10.1038/nprot.2007.411

    Nature Protocols 2; 3115 - 3121 (2007)

    Published online: 06 December 2007

    Abstract | Full Text | PDF (337K)

  • Protocol

    Synthesis of anhydride precursors of the environment-sensitive fluorophores 4-DMAP and 6-DMN

    Matthieu Sainlos & Barbara Imperiali

    doi:10.1038/nprot.2007.444

    Nature Protocols 2; 3219 - 3225 (2007)

    Published online: 13 December 2007

    Abstract | Full Text | PDF (168K)

  • Protocol

    Synthesis of the 3'-thio-nucleosides and subsequent automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage

    James W Gaynor, Joanne Bentley & Richard Cosstick

    doi:10.1038/nprot.2007.451

    Nature Protocols 2; 3122 - 3135 (2007)

    Published online: 06 December 2007

    Abstract | Full Text | PDF (292K)

  • Protocol

    Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences

    Irene Coin, Michael Beyermann & Michael Bienert

    doi:10.1038/nprot.2007.454

    Nature Protocols 2; 3247 - 3256 (2007)

    Published online: 13 December 2007

    Abstract | Full Text | PDF (286K)

  • Protocol

    Synthesis of cationic single-isomer cyclodextrins for the chiral separation of amino acids and anionic pharmaceuticals

    Weihua Tang & Siu-Choon Ng

    doi:10.1038/nprot.2007.479

    Nature Protocols 2; 3195 - 3200 (2007)

    Published online: 06 December 2007

    Abstract | Full Text | PDF (169K)

  • Review

    The remarkable metal-catalysed olefin metathesis reaction

    Amir H. Hoveyda & Adil R. Zhugralin

    doi:10.1038/nature06351

    Nature 450; 243 - 251 (2007)

    Abstract | Full Text | PDF (476K)

  • Brief Communication

    Sortagging: a versatile method for protein labeling

    Maximilian W Popp, John M Antos, Gijsbert M Grotenbreg, Eric Spooner & Hidde L Ploegh

    doi:10.1038/nchembio.2007.31

    Nature Chemical Biology 3; 707 - 708 (2007)

    Published online: 23 September 2007

    Abstract | Full Text | PDF (1,468K)

  • Protocol

    Fabrication of carbohydrate chips and their use to probe protein–carbohydrate interactions

    Sungjin Park, Myung-Ryul Lee & Injae Shin

    doi:10.1038/nprot.2007.373

    Nature Protocols 2; 2747 - 2758 (2007)

    Published online: 01 November 2007

    Abstract | Full Text | PDF (327K)

  • Protocol

    Preparation of chiral derivatives of bold beta-Ala containing the alpha-phenylethyl group: useful starting materials for the asymmetric synthesis of bold beta-amino acids

    Ramón Guzmán-Mejía, Gloria Reyes-Rangel & Eusebio Juaristi

    doi:10.1038/nprot.2007.375

    Nature Protocols 2; 2759 - 2766 (2007)

    Published online: 01 November 2007

    Abstract | Full Text | PDF (369K)

  • Protocol

    Synthesis of poly(L-lactide) and polyglycolide by ring-opening polymerization

    Sachiko Kaihara, Shuichi Matsumura, Antonios G Mikos & John P Fisher

    doi:10.1038/nprot.2007.391

    Nature Protocols 2; 2767 - 2771 (2007)

    Published online: 01 November 2007

    Abstract | Full Text | PDF (225K)

  • Protocol

    Pd-catalyzed amination reactions of aryl halides using bulky biarylmonophosphine ligands

    Ryan A Altman, Brett P Fors & Stephen L Buchwald

    doi:10.1038/nprot.2007.414

    Nature Protocols 2; 2881 - 2887 (2007)

    Published online: 08 November 2007

    Abstract | Full Text | PDF (304K)

  • Protocol

    A gold nanoparticle-based chronocoulometric DNA sensor for amplified detection of DNA

    Jiong Zhang, Shiping Song, Lihua Wang, Dun Pan & Chunhai Fan

    doi:10.1038/nprot.2007.419

    Nature Protocols 2; 2888 - 2895 (2007)

    Published online: 08 November 2007

    Abstract | Full Text | PDF (298K)

  • Protocol

    Preparation of arylzinc reagents and their use in the rhodium-catalyzed asymmetric 1,4-addition for the synthesis of 2-aryl-4-piperidones

    Ryo Shintani & Tamio Hayashi

    doi:10.1038/nprot.2007.424

    Nature Protocols 2; 2903 - 2909 (2007)

    Published online: 08 November 2007

    Abstract | Full Text | PDF (279K)

  • Letter

    Robust immune responses elicited by a fully synthetic three-component vaccine

    Sampat Ingale, Margreet A Wolfert, Jidnyasa Gaekwad, Therese Buskas & Geert-Jan Boons

    doi:10.1038/nchembio.2007.25

    Nature Chemical Biology 3; 663 - 667 (2007)

    Published online: 02 September 2007

    Abstract | Full Text | PDF (1,502K)

  • Letter

    Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution

    Gavin J Williams, Changsheng Zhang & Jon S Thorson

    doi:10.1038/nchembio.2007.28

    Nature Chemical Biology 3; 657 - 662 (2007)

    Published online: 09 September 2007

    Abstract | Full Text | PDF (1,611K)

  • Protocol

    Synthesis of lactones using substituted benzoic anhydride as a coupling reagent

    Isamu Shiina, Hiroki Fukui & Akane Sasaki

    doi:10.1038/nprot.2007.316

    Nature Protocols 2; 2312 - 2317 (2007)

    Published online: 20 September 2007

    Abstract | Full Text | PDF (280K)

  • Protocol

    Methods of using click chemistry in the discovery of enzyme inhibitors

    Rajavel Srinivasan, Junqi Li, Su Ling Ng, Karunakaran A Kalesh & Shao Q Yao

    doi:10.1038/nprot.2007.323

    Nature Protocols 2; 2655 - 2664 (2007)

    Published online: 25 October 2007

    Abstract | Full Text | PDF (474K)

  • Protocol

    Synthesis, encapsulation, purification and coupling of single quantum dots in phospholipid micelles for their use in cellular and in vivo imaging

    Olivier Carion, Benoît Mahler, Thomas Pons & Benoit Dubertret

    doi:10.1038/nprot.2007.351

    Nature Protocols 2; 2383 - 2390 (2007)

    Published online: 27 September 2007

    Abstract | Full Text | PDF (513K)

  • Protocol

    Preparation, application and testing of permanent antibacterial and antiviral coatings

    Jayanta Haldar, Alisha K Weight & Alexander M Klibanov

    doi:10.1038/nprot.2007.353

    Nature Protocols 2; 2412 - 2417 (2007)

    Published online: 27 September 2007

    Abstract | Full Text | PDF (334K)

  • Protocol

    Mosher ester analysis for the determination of absolute configuration of stereogenic (chiral) carbinol carbons

    Thomas R Hoye, Christopher S Jeffrey & Feng Shao

    doi:10.1038/nprot.2007.354

    Nature Protocols 2; 2451 - 2458 (2007)

    Published online: 04 October 2007

    Abstract | Full Text | PDF (246K)

  • Protocol

    Cu-catalyzed Goldberg and Ullmann reactions of aryl halides using chelating N- and O-based ligands

    Ryan A Altman & Stephen L Buchwald

    doi:10.1038/nprot.2007.364

    Nature Protocols 2; 2474 - 2479 (2007)

    Published online: 04 October 2007

    Abstract | Full Text | PDF (307K)

  • Protocol

    An expedient, facile and simple one-pot synthesis of 2-methylenealkanoates and alkanenitriles from the Baylis–Hillman bromides in aqueous media

    Deevi Basavaiah, Kanumuri Ramesh Reddy & Nagaswamy Kumaragurubaran

    doi:10.1038/nprot.2007.369

    Nature Protocols 2; 2665 - 2676 (2007)

    Published online: 25 October 2007

    Abstract | Full Text | PDF (284K)

  • Protocol

    Asymmetric aldol reaction using boron enolates

    Katie M Cergol & Mark J Coster

    doi:10.1038/nprot.2007.372

    Nature Protocols 2; 2568 - 2573 (2007)

    Published online: 11 October 2007

    Abstract | Full Text | PDF (265K)

  • Protocol

    Rapid solid-phase synthesis of a calmodulin-binding peptide using controlled microwave irradiation

    Bernadett Bacsa & C Oliver Kappe

    doi:10.1038/nprot.2007.300

    Nature Protocols 2; 2222 - 2227 (2007)

    Published online: 13 September 2007

    Abstract | Full Text | PDF (222K)

  • Protocol

    Inhibitor fingerprinting of metalloproteases using microplate and microarray platforms: an enabling technology in Catalomics

    Wei L Lee, Junqi Li, Mahesh Uttamchandani, Hongyan Sun & Shao Q Yao

    doi:10.1038/nprot.2007.305

    Nature Protocols 2; 2126 - 2138 (2007)

    Published online: 30 August 2007

    Abstract | Full Text | PDF (435K)

  • Protocol

    Facile synthesis of Ag nanocubes and Au nanocages

    Sara E Skrabalak, Leslie Au, Xingde Li & Younan Xia

    doi:10.1038/nprot.2007.326

    Nature Protocols 2; 2182 - 2190 (2007)

    Published online: 06 September 2007

    Abstract | Full Text | PDF (561K)

  • Protocol

    The partial reduction of electron-deficient pyrroles: procedures describing both Birch (Li/NH3) and ammonia-free (Li/DBB) conditions

    Timothy J Donohoe & Rhian E Thomas

    doi:10.1038/nprot.2007.245

    Nature Protocols 2; 1888 - 1895 (2007)

    Published online: 02 August 2007

    Abstract | Full Text | PDF (371K)

  • Protocol

    Preparation of the functionalizable methionine surrogate azidohomoalanine via copper-catalyzed diazo transfer

    A James Link, Mandy K S Vink & David A Tirrell

    doi:10.1038/nprot.2007.268

    Nature Protocols 2; 1879 - 1883 (2007)

    Published online: 26 July 2007

    Abstract | Full Text | PDF (172K)

  • Protocol

    Synthesis of the functionalizable methionine surrogate azidohomoalanine using Boc-homoserine as precursor

    A James Link, Mandy K S Vink & David A Tirrell

    doi:10.1038/nprot.2007.269

    Nature Protocols 2; 1884 - 1887 (2007)

    Published online: 26 July 2007

    Abstract | Full Text | PDF (140K)

  • Protocol

    Practical Proline-catalyzed asymmetric Mannich reaction of aldehydes with N-Boc-imines

    Jung Woon Yang, Michael Stadler & Benjamin List

    doi:10.1038/nprot.2007.272

    Nature Protocols 2; 1937 - 1942 (2007)

    Published online: 02 August 2007

    Abstract | Full Text | PDF (225K)

  • Protocol

    Site-specific incorporation of nitroxide spin-labels into 2'-positions of nucleic acids

    Thomas E Edwards & Snorri Th Sigurdsson

    doi:10.1038/nprot.2007.273

    Nature Protocols 2; 1954 - 1962 (2007)

    Published online: 09 August 2007

    Abstract | Full Text | PDF (321K)

  • Protocol

    Synthesis of pyrimidines by direct condensation of amides and nitriles

    Mohammad Movassaghi & Matthew D Hill

    doi:10.1038/nprot.2007.280

    Nature Protocols 2; 2018 - 2023 (2007)

    Published online: 16 August 2007

    Abstract | Full Text | PDF (171K)

  • Review

    Modern synthetic efforts toward biologically active terpenes

    Thomas J Maimone & Phil S Baran

    doi:10.1038/nchembio.2007.1

    Nature Chemical Biology 3; 396 - 407 (2007)

    Published online: 18 June 2007

    Abstract | Full Text | PDF (948K)

  • Protocol

    Automated generation of a dihydropyrimidine compound library using microwave-assisted processing

    Doris Dallinger & C Oliver Kappe

    doi:10.1038/nprot.2007.224

    Nature Protocols 2; 1713 - 1721 (2007)

    Published online: 05 July 2007

    Abstract | Full Text | PDF (718K)

  • Protocol

    Synthesis of a highly metal-selective rhodamine-based probe and its use for the in vivo monitoring of mercury

    Young-Keun Yang, Sung-Kyun Ko, Injae Shin & Jinsung Tae

    doi:10.1038/nprot.2007.246

    Nature Protocols 2; 1740 - 1745 (2007)

    Published online: 05 July 2007

    Abstract | Full Text | PDF (319K)

  • Protocol

    Direct ester condensation catalyzed by bulky diarylammonium pentafluorobenzenesulfonates

    Akira Sakakura, Shoko Nakagawa & Kazuaki Ishihara

    doi:10.1038/nprot.2007.254

    Nature Protocols 2; 1746 - 1751 (2007)

    Published online: 05 July 2007

    Abstract | Full Text | PDF (283K)

  • Protocol

    Pyruvate aldolases in chiral carbon–carbon bond formation

    Matthew J Walters & Eric J Toone

    doi:10.1038/nprot.2007.260

    Nature Protocols 2; 1825 - 1830 (2007)

    Published online: 19 July 2007

    Abstract | Full Text | PDF (160K)

  • Letter

    Production of dimethylfuran for liquid fuels from biomass-derived carbohydrates

    Yuriy Román-Leshkov, Christopher J. Barrett, Zhen Y. Liu & James A. Dumesic

    doi:10.1038/nature05923

    Nature 447; 982 - 985 (2007)

    Abstract | Full Text | PDF (300K)

  • Brief Communication

    Introducing genetically encoded aldehydes into proteins

    Isaac S Carrico, Brian L Carlson & Carolyn R Bertozzi

    doi:10.1038/nchembio878

    Nature Chemical Biology 3; 321 - 322 (2007)

    Published online: 22 April 2007

    Abstract | Full Text | PDF (470K)

  • Letter

    Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

    Sovan Sarkar, Ethan O Perlstein, Sara Imarisio, Sandra Pineau, Axelle Cordenier, Rebecca L Maglathlin, John A Webster, Timothy A Lewis, Cahir J O'Kane, Stuart L Schreiber & David C Rubinsztein

    doi:10.1038/nchembio883

    Nature Chemical Biology 3; 331 - 338 (2007)

    Published online: 07 May 2007

    Abstract | Full Text | PDF (622K)

  • Protocol

    Versatile synthesis of oligodeoxyribonucleotide–oligospermine conjugates

    Emilie Voirin, Jean-Paul Behr & Mitsuharu Kotera

    doi:10.1038/nprot.2007.177

    Nature Protocols 2; 1360 - 1367 (2007)

    Published online: 24 May 2007

    Abstract | Full Text | PDF (263K)

  • Protocol

    Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)—a general method for mapping sites of probe modification in proteomes

    Eranthie Weerapana, Anna E Speers & Benjamin F Cravatt

    doi:10.1038/nprot.2007.194

    Nature Protocols 2; 1414 - 1425 (2007)

    Published online: 31 May 2007

    Abstract | Full Text | PDF (299K)

  • Protocol

    Synthesis and utilization of reversible and irreversible light-activated nanovalves derived from the channel protein MscL

    Armag brevean Koçer, Martin Walko & Ben L Feringa

    doi:10.1038/nprot.2007.196

    Nature Protocols 2; 1426 - 1437 (2007)

    Published online: 31 May 2007

    Abstract | Full Text | PDF (372K)

  • Protocol

    Synthesis and enzymatic incorporation of a fluorescent pyrimidine ribonucleotide

    Seergazhi G Srivatsan & Yitzhak Tor

    doi:10.1038/nprot.2007.222

    Nature Protocols 2; 1547 - 1555 (2007)

    Published online: 14 June 2007

    Abstract | Full Text | PDF (247K)

  • Letter

    Molecular imaging of hydrogen peroxide produced for cell signaling

    Evan W Miller, Orapim Tulyathan, Ehud Y Isacoff & Christopher J Chang

    doi:10.1038/nchembio871

    Nature Chemical Biology 3; 263 - 267 (2007)

    Published online: 01 April 2007

    Abstract | Full Text | PDF (403K)

  • Protocol

    Synthesis of oligo-RNAs with photocaged adenosine 2'-hydroxyls

    Steven G Chaulk & Andrew M MacMillan

    doi:10.1038/nprot.2007.154

    Nature Protocols 2; 1052 - 1058 (2007)

    Published online: 26 April 2007

    Abstract | Full Text | PDF (212K)

  • Protocol

    Site-specific incorporation of fluorotyrosines into the R2 subunit of E. coli ribonucleotide reductase by expressed protein ligation

    Mohammad R Seyedsayamdost, Cyril S Yee & JoAnne Stubbe

    doi:10.1038/nprot.2007.159

    Nature Protocols 2; 1225 - 1235 (2007)

    Published online: 10 May 2007

    Abstract | Full Text | PDF (375K)

  • Protocol

    A simple one-pot multicomponent synthesis of an octahedral nanocontainer molecule

    Xuejun Liu & Ralf Warmuth

    doi:10.1038/nprot.2007.193

    Nature Protocols 2; 1288 - 1296 (2007)

    Published online: 17 May 2007

    Abstract | Full Text | PDF (323K)

  • Article

    Structure-guided development of affinity probes for tyrosine kinases using chemical genetics

    Jimmy A Blair, Daniel Rauh, Charles Kung, Cai-Hong Yun, Qi-Wen Fan, Haridas Rode, Chao Zhang, Michael J Eck, William A Weiss & Kevan M Shokat

    doi:10.1038/nchembio866

    Nature Chemical Biology 3; 229 - 238 (2007)

    Published online: 04 March 2007

    Abstract | Full Text | PDF (1,861K)

  • Brief Communication

    Discovery of a natural thiamine adenine nucleotide

    Lucien Bettendorff, Barbara Wirtzfeld, Alexander F Makarchikov, Gabriel Mazzucchelli, Michel Frédérich, Tiziana Gigliobianco, Marjorie Gangolf, Edwin De Pauw, Luc Angenot & Pierre Wins

    doi:10.1038/nchembio867

    Nature Chemical Biology 3; 211 - 212 (2007)

    Published online: 04 March 2007

    Abstract | Full Text | PDF (1,423K)

  • Letter

    Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells

    Prasanna Venkatraman, Tina T Nguyen, Matthieu Sainlos, Osman Bilsel, Sriram Chitta, Barbara Imperiali & Lawrence J Stern

    doi:10.1038/nchembio868

    Nature Chemical Biology 3; 222 - 228 (2007)

    Published online: 11 March 2007

    Abstract | Full Text | PDF (1,681K)

  • Letter

    Temperature-mediated growth of single-walled carbon-nanotube intramolecular junctions

    Yagang Yao, Qingwen Li, Jin Zhang, Ran Liu, Liying Jiao, Yuntian T. Zhu & Zhongfan Liu

    doi:10.1038/nmat1865

    Nature Materials 6; 283 - 286 (2007)

    Published online: 18 March 2007

    Abstract | Full Text | PDF (288K)

  • Protocol

    Practical and convenient synthesis of coumarins from phenols and propiolic acid esters

    Tsugio Kitamura, Juzo Oyamada & Toshiki Tsubota

    doi:10.1038/nprot.2007.103

    Nature Protocols 2; 845 - 848 (2007)

    Published online: 05 April 2007

    Abstract | Full Text | PDF (135K)

  • Protocol

    An improved synthesis of NHS-MAG3 for conjugation and radiolabeling of biomolecules with 99mTc at room temperature

    Yi Wang, Xinrong Liu & Donald J Hnatowich

    doi:10.1038/nprot.2007.144

    Nature Protocols 2; 972 - 978 (2007)

    Published online: 19 April 2007

    Abstract | Full Text | PDF (208K)

  • Protocol

    Spin labeling of oligonucleotides with the nitroxide TPA and use of PELDOR, a pulse EPR method, to measure intramolecular distances

    Olav Schiemann, Nelly Piton, Jörn Plackmeyer, Bela E Bode, Thomas F Prisner & Joachim W Engels

    doi:10.1038/nprot.2007.97

    Nature Protocols 2; 904 - 923 (2007)

    Published online: 12 April 2007

    Abstract | Full Text | PDF (622K)

  • Article

    Total synthesis of marine natural products without using protecting groups

    Phil S. Baran, Thomas J. Maimone & Jeremy M. Richter

    doi:10.1038/nature05569

    Nature 446; 404 - 408 (2007)

    Abstract | Full Text | PDF (463K)

  • Letter

    A clickable inhibitor reveals context-dependent autoactivation of p90 RSK

    Michael S Cohen, Haralambos Hadjivassiliou & Jack Taunton

    doi:10.1038/nchembio859

    Nature Chemical Biology 3; 156 - 160 (2007)

    Published online: 28 January 2007

    Abstract | Full Text | PDF (545K)

  • Letter

    A novel hybrid carbon material

    Albert G. Nasibulin, Peter V. Pikhitsa, Hua Jiang, David P. Brown, Arkady V. Krasheninnikov, Anton S. Anisimov, Paula Queipo, Anna Moisala, David Gonzalez, Günther Lientschnig, Abdou Hassanien, Sergey D. Shandakov, Giulio Lolli, Daniel E. Resasco, Mansoo Choi, David Tománek & Esko I. Kauppinen

    doi:10.1038/nnano.2007.37

    Nature Nanotechnology 2; 156 - 161 (2007)

    Published online: 25 February 2007

    Abstract | Full Text | PDF (673K)

  • Protocol

    DNA base mismatch detection with bulky rhodium intercalators: synthesis and applications

    Brian M Zeglis & Jacqueline K Barton

    doi:10.1038/nprot.2007.22

    Nature Protocols 2; 357 - 371 (2007)

    Published online: 08 March 2007

    Abstract | Full Text | PDF (641K)

  • Protocol

    Parallel synthesis of peptide libraries using microwave irradiation

    Justin K Murray & Samuel H Gellman

    doi:10.1038/nprot.2007.23

    Nature Protocols 2; 624 - 631 (2007)

    Published online: 22 March 2007

    Abstract | Full Text | PDF (1,112K)

  • Protocol

    Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging

    Daniela C Dieterich, Jennifer J Lee, A James Link, Johannes Graumann, David A Tirrell & Erin M Schuman

    doi:10.1038/nprot.2007.52

    Nature Protocols 2; 532 - 540 (2007)

    Published online: 15 March 2007

    Abstract | Full Text | PDF (276K)

  • Protocol

    In vitro screening for molecules that affect virus capsid assembly (and other protein association reactions)

    Adam Zlotnick, Angela Lee, Christina R Bourne, Jennifer M Johnson, Paul L Domanico & Stephen J Stray

    doi:10.1038/nprot.2007.60

    Nature Protocols 2; 490 - 498 (2007)

    Published online: 15 March 2007

    Abstract | Full Text | PDF (281K)

  • Protocol

    The use of the Ugi four-component condensation

    Stefano Marcaccini & Tomás Torroba

    doi:10.1038/nprot.2007.71

    Nature Protocols 2; 632 - 639 (2007)

    Published online: 22 March 2007

    Abstract | Full Text | PDF (251K)

  • Protocol

    Selenium modification of nucleic acids: preparation of phosphoroselenoate derivatives for crystallographic phasing of nucleic acid structures

    Pradeep S Pallan & Martin Egli

    doi:10.1038/nprot.2007.74

    Nature Protocols 2; 640 - 646 (2007)

    Published online: 22 March 2007

    Abstract | Full Text | PDF (277K)

  • Protocol

    Selenium modification of nucleic acids: preparation of oligonucleotides with incorporated 2'-SeMe-uridine for crystallographic phasing of nucleic acid structures

    Pradeep S Pallan & Martin Egli

    doi:10.1038/nprot.2007.75

    Nature Protocols 2; 647 - 651 (2007)

    Published online: 22 March 2007

    Abstract | Full Text | PDF (190K)

  • Protocol

    Synthesis and oligonucleotide incorporation of fluorescent cytosine analogue tC: a promising nucleic acid probe

    Peter Sandin, Per Lincoln, Tom Brown & L Marcus Wilhelmsson

    doi:10.1038/nprot.2007.80

    Nature Protocols 2; 615 - 623 (2007)

    Published online: 22 March 2007

    Abstract | Full Text | PDF (194K)

  • Article

    A flexible interpenetrating coordination framework with a bimodal porous functionality

    Tapas Kumar Maji, Ryotaro Matsuda & Susumu Kitagawa

    doi:10.1038/nmat1827

    Nature Materials 6; 142 - 148 (2007)

    Published online: 28 January 2007

    Abstract | Full Text | PDF (766K)

  • Protocol

    Synthesis and use of an in-solution ratiometric fluorescent viscosity sensor

    Derek Fischer, Emmanuel A Theodorakis & Mark A Haidekker

    doi:10.1038/nprot.2006.455

    Nature Protocols 2; 227 - 236 (2007)

    Published online: 08 February 2007

    Abstract | Full Text | PDF (238K)

  • Protocol

    Synthesis of azobenzene-tethered DNA for reversible photo-regulation of DNA functions: hybridization and transcription

    Hiroyuki Asanuma, Xingguo Liang, Hidenori Nishioka, Daijiro Matsunaga, Mingzhe Liu & Makoto Komiyama

    doi:10.1038/nprot.2006.465

    Nature Protocols 2; 203 - 212 (2007)

    Published online: 08 February 2007

    Abstract | Full Text | PDF (430K)

  • Protocol

    L-Proline-catalyzed enantioselective one-pot cross-Mannich reaction of aldehydes

    Yujiro Hayashi, Tatsuya Urushima, Wataru Tsuboi & Mitsuru Shoji

    doi:10.1038/nprot.2006.472

    Nature Protocols 2; 113 - 118 (2007)

    Published online: 15 February 2007

    Abstract | Full Text | PDF (167K)

  • Protocol

    Synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate: a radio-iodination agent for labeling internalizing proteins and peptides

    Ganesan Vaidyanathan & Michael R Zalutsky

    doi:10.1038/nprot.2007.20

    Nature Protocols 2; 282 - 286 (2007)

    Published online: 01 March 2007

    Abstract | Full Text | PDF (179K)

  • Protocol

    Synthesis of 3,3'-bis(sulfonato)-4,4'-bis(chloroacetamido)azobenzene and cysteine cross-linking for photo-control of protein conformation and activity

    Darcy C Burns, Fuzhong Zhang & G Andrew Woolley

    doi:10.1038/nprot.2007.21

    Nature Protocols 2; 251 - 258 (2007)

    Published online: 08 March 2007

    Abstract | Full Text | PDF (283K)

  • Protocol

    Substrate activity screening (SAS): a general procedure for the preparation and screening of a fragment-based non-peptidic protease substrate library for inhibitor discovery

    Andrew W Patterson, Warren J L Wood & Jonathan A Ellman

    doi:10.1038/nprot.2007.28

    Nature Protocols 2; 424 - 433 (2007)

    Published online: 08 March 2007

    Abstract | Full Text | PDF (233K)

  • Protocol

    Preparation of a copper-based fluorescent probe for nitric oxide and its use in mammalian cultured cells

    Mi Hee Lim

    doi:10.1038/nprot.2007.43

    Nature Protocols 2; 408 - 415 (2007)

    Published online: 08 March 2007

    Abstract | Full Text | PDF (215K)

  • Protocol

    Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU

    Suren Soghomonyan, Amin Hajitou, Roberto Rangel, Martin Trepel, Renata Pasqualini, Wadih Arap, Juri G Gelovani & Mian M Alauddin

    doi:10.1038/nprot.2007.49

    Nature Protocols 2; 416 - 423 (2007)

    Published online: 08 March 2007

    Abstract | Full Text | PDF (267K)

  • Protocol

    Preparation of substituted anilines from nitro compounds by using supported gold catalysts

    Avelino Corma & Pedro Serna

    doi:10.1038/nprot.2006.441

    Nature Protocols 1; 2590 - 2595 (2007)

    Published online: 11 January 2007

    Abstract | Full Text | PDF (217K)

  • Protocol

    Thermal and high pressure intramolecular Diels–Alder reaction of vinylsulfonamides

    Victor O Rogachev & Peter Metz

    doi:10.1038/nprot.2006.463

    Nature Protocols 1; 3076 - 3087 (2007)

    Published online: 25 January 2007

    Abstract | Full Text | PDF (442K)

  • Protocol

    Dehydroalanine-containing peptides: preparation from phenylselenocysteine and utility in convergent ligation strategies

    Matthew R Levengood & Wilfred A van der Donk

    doi:10.1038/nprot.2006.470

    Nature Protocols 1; 3001 - 3010 (2007)

    Published online: 25 January 2007

    Abstract | Full Text | PDF (343K)

  • Protocol

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    Jinq-Chyi Lee, William A Greenberg & Chi-Huey Wong

    doi:10.1038/nprot.2006.489

    Nature Protocols 1; 3143 - 3152 (2007)

    Published online: 31 January 2007

    Abstract | Full Text | PDF (267K)

  • Protocol

    Synthesis of TOAC spin-labeled proteins and reconstitution in lipid membranes

    Christine B Karim, Zhiwen Zhang & David D Thomas

    doi:10.1038/nprot.2007.2

    Nature Protocols 2; 42 - 49 (2007)

    Published online: 31 January 2007

    Abstract | Full Text | PDF (248K)

  • Protocol

    One-pot three-enzyme chemoenzymatic approach to the synthesis of sialosides containing natural and non-natural functionalities

    Hai Yu, Harshal A. Chokhawala, Shengshu Huang & Xi Chen

    doi:10.1038/nprot.2006.401

    Nature Protocols 1; 2485 - 2492 (2006)

    Published online: 11 January 2007

    Abstract | Full Text | PDF (1,483K)


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