Cancer Gene Therapy TOP TEN

The top ten charts the articles that have been downloaded most often, in HTML format, from the Cancer Gene Therapy website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

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October 2009

  1. Comparative assessment of siRNA and shRNA off target effects: what is slowing clinical development

    D D Rao, N Senzer, M A Cleary and J Nemunaitis

    doi:10.1038/cgt.2009.53

  2. Viruses, gene therapy and stem cells for the treatment of human glioma

    A P Kyritsis, C Sioka and J S Rao

    doi:10.1038/cgt.2009.52

  3. RNA interference-mediated knockdown of p21WAF1 enhances anti-tumor cell activity of oncolytic adenoviruses FREE

    M Shiina, M D Lacher, C Christian and W M Korn

    doi:10.1038/cgt.2009.29

  4. Lentiviruses with trastuzumab bound to their envelopes can target and kill prostate cancer cells

    K-x Zhang, M Moussavi, C Kim, E Chow, I S Chen, L Fazli, W Jia and P S Rennie

    doi:10.1038/cgt.2009.28

  5. Novel strategies to augment genetically delivered immunotoxin molecular therapy for cancer therapy

    X Liu, J Wu, S Zhang, C Li and Q Huang

    doi:10.1038/cgt.2009.30

  6. Recent advances in p53 research: an interdisciplinary perspective FREE

    M Olivier, A Petitjean, V Marcel, A Pétré, M Mounawar, A Plymoth, C C de Fromentel and P Hainaut

    doi:10.1038/cgt.2008.69

  7. Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo

    E Rognoni, M Widmaier, C Haczek, K Mantwill, R Holzmüller, B Gansbacher, A Kolk, T Schuster, R M Schmid, D Saur, A Kaszubiak, H Lage and P S Holm

    doi:10.1038/cgt.2009.20

  8. Inhibition of tumor growth and induction of apoptosis in prostate cancer cell lines by overexpression of tissue inhibitor of matrix metalloproteinase-3

    L Zhang, L Zhao, D Zhao, G Lin, B Guo, Y Li, Z Liang, X J Zhao and X Fang

    doi:10.1038/cgt.2009.59

  9. Paclitaxel combined with siRNA targeting HPV16 oncogenes improves cytotoxicity for cervical carcinoma

    W-l Liu, N Green, L W Seymour and M Stevenson

    doi:10.1038/cgt.2009.24

  10. Combination of human tumor necrosis factor-alpha (hTNF-alpha) gene delivery with gemcitabine is effective in models of pancreatic cancer

    S R Murugesan, C R King, R Osborn, W R Fairweather, E M O'Reilly, M O Thornton and L L Wei

    doi:10.1038/cgt.2009.32

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