ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
Original Articles
July 25 2008
Recombinant vesicular stomatitis virus targeted to Her2/neu combined with anti-CTLA4 antibody eliminates implanted mammary tumors
Y Gao, P Whitaker-Dowling, J A Griffin, M A Barmada and I Bergman
Cancer Gene Ther advance online publication, July 25, 2008; doi:10.1038/cgt.2008.55
REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer
K Kawasaki, M Watanabe, M Sakaguchi, Y Ogasawara, K Ochiai, Y Nasu, H Doihara, Y Kashiwakura, N-h Huh, H Kumon and H Date
Cancer Gene Ther advance online publication, July 25, 2008; doi:10.1038/cgt.2008.58
IL-18-producing Salmonella inhibit tumor growth
M Loeffler, G Le'Negrate, M Krajewska and J C Reed
Cancer Gene Ther advance online publication, July 25, 2008; doi:10.1038/cgt.2008.48
Abstract | Full Text | PDF | Supplementary information
Chimeric form of tumor necrosis factor-
has enhanced surface expression and antitumor activity
R Rieger, D Whitacre, M J Cantwell, C Prussak and T J Kipps
Cancer Gene Ther advance online publication, July 25, 2008; doi:10.1038/cgt.2008.57
Combination therapy with short interfering RNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model
M-A Shibata, J Morimoto, E Shibata and Y Otsuki
Cancer Gene Ther advance online publication, July 25, 2008; doi:10.1038/cgt.2008.43
Early RB94-produced cytotoxicity in cancer cells is independent of caspase activation or 50 kb DNA fragmentation
J Zhou, X-Q Zhang, F Ashoori, D J McConkey, M A Knowles, L Dong and W F Benedict
Cancer Gene Ther advance online publication, July 25, 2008; doi:10.1038/cgt.2008.54
July 11 2008
Intratumoral gene delivery of anti-cathepsin L single-chain variable fragment by lentiviral vector inhibits tumor progression induced by human melanoma cells
R Frade, N Rousselet and D Jean
Cancer Gene Ther advance online publication, July 11, 2008; doi:10.1038/cgt.2008.51
Adenovirus-mediated HCCS1 overexpression elicits a potent antitumor efficacy on human colorectal cancer and hepatoma cells both in vitro and in vivo
Y Gan, J Gu, X Cai, J Hu, X Y Liu and X Zhao
Cancer Gene Ther advance online publication, July 11, 2008; doi:10.1038/cgt.2008.52
Polyethylenimine-mediated in vivo gene transfer of a transmembrane superantigen fusion construct inhibits B16 murine melanoma growth
G Jeudy, F Salvadori, B Chauffert, E Solary, P Vabres and J Chluba
Cancer Gene Ther advance online publication, July 11, 2008; doi:10.1038/cgt.2008.42
Conditioned medium from Ad-IFN--infected bladder cancer and normal urothelial cells is cytotoxic to cancer cells but not normal cells: further evidence for a strong bystander effect
X Zhang, L Dong, E Chapman and W F Benedict
Cancer Gene Ther advance online publication, July 11, 2008; doi:10.1038/cgt.2008.53
July 4 2008
Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43
S Cottin, K Ghani and M Caruso
Cancer Gene Ther advance online publication, July 4, 2008; doi:10.1038/cgt.2008.49
Adenovirus-mediated gene transfer of interleukin-23 shows prophylactic but not therapeutic antitumor effects
H-T Jin, J-I Youn, S-Y Choi, S-H Seo, S-H Park, M-Y Song, S-H Yang and Y-C Sung
Cancer Gene Ther advance online publication, July 4, 2008; doi:10.1038/cgt.2008.41
Enhanced delivery efficiency of recombinant adenovirus into tumor and mesenchymal stem cells by a novel PTD
J-I Youn, S-H Park, H-T Jin, C-G Lee, S-H Seo, M-Y Song, C-W Lee and Y-C Sung
Cancer Gene Ther advance online publication, July 4, 2008; doi:10.1038/cgt.2008.45
June 27 2008
ONYX-411, a conditionally replicative oncolytic adenovirus, induces cell death in anaplastic thyroid carcinoma cell lines and suppresses the growth of xenograft tumors in nude mice
H V Reddi, P Madde, A J Reichert-Eberhardt, E C Galanis, J A Copland, B McIver, S K G Grebe and N L Eberhardt
Cancer Gene Ther advance online publication, June 27, 2008; doi:10.1038/cgt.2008.44
June 20 2008
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells
W Song, Z Dong, T Jin, M G Mantellini, G Núñez and J E Nör
Cancer Gene Ther advance online publication, June 20, 2008; doi:10.1038/cgt.2008.38
June 13 2008
Molecular analysis of human cancer cells infected by an oncolytic HSV-1 reveals multiple upregulated cellular genes and a role for SOCS1 in virus replication
Y Y Mahller, B Sakthivel, W H Baird, B J Aronow, Y-H Hsu, T P Cripe and R Mehrian-Shai
Cancer Gene Ther advance online publication, June 13, 2008; doi:10.1038/cgt.2008.40
Abstract | Full Text | PDF | Supplementary information
Adenoviral-mediated Rybp expression promotes tumor cell-specific apoptosis
R L Novak and A C Phillips
Cancer Gene Ther advance online publication, June 13, 2008; doi:10.1038/cgt.2008.25
Hypoxia-induced human endonuclease G expression suppresses tumor growth in a xenograft model
P T Winnard Jr, M Botlagunta, J B Kluth, S Mukadam, B Krishnamachary, F Vesuna and V Raman
Cancer Gene Ther advance online publication, June 13, 2008; doi:10.1038/cgt.2008.39
June 6 2008
Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapy
Y Gao, S S M Ng, D H W Chau, H Yao, C Yang, K Man, P T Huang, C Huang, J J Huang, H-F Kung and M C Lin
Cancer Gene Ther advance online publication, June 6, 2008; doi:10.1038/cgt.2008.33
Abstract | Full Text | PDF | Supplementary information
HSV-1 amplicon viral vector-mediated gene transfer to human bone marrow-derived mesenchymal stem cells
I A W Ho, K Y W Chan, L Miao, W S N Shim, C M Guo, P Cheang, K M Hui and P Y P Lam
Cancer Gene Ther advance online publication, June 6, 2008; doi:10.1038/cgt.2008.27
JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase
W Hu, W Hofstetter, W Guo, H Li, A Pataer, H H Peng, Z S Guo, D L Bartlett, A Lin, S G Swisher and B Fang
Cancer Gene Ther advance online publication, June 6, 2008; doi:10.1038/cgt.2008.32
Abstract | Full Text | PDF | Supplementary information
Phase I trial of DNA-hsp65 immunotherapy for advanced squamous cell carcinoma of the head and neck
P Michaluart, K A Abdallah, F D Lima, R Smith, R A Moysés, V Coelho, G D Victora, A Socorro-Silva, E C Volsi, C R Zárate-Bladés, A R Ferraz, A K Barreto, M C Chammas, R Gomes, E Gebrim, L Arakawa-Sugueno, K P Fernandes, P A Lotufo, M R Cardoso, J Kalil and C L Silva
Cancer Gene Ther advance online publication, June 6, 2008; doi:10.1038/cgt.2008.35
Dual induction of PKR with E2F-1 and IFN- to enhance gene therapy against hepatocellular carcinoma
V Roh, A Laemmle, U Von Holzen, D Stroka, J-F Dufour, K K Hunt, D Candinas and S A Vorburger
Cancer Gene Ther advance online publication, June 6, 2008; doi:10.1038/cgt.2008.34
Tissue-type plasminogen activator has antiangiogenic properties without effect on tumor growth in a rat C6 glioma model
F Solly, R Fish, B Simard, N Bolle, E Kruithof, B Polack and G Pernod
Cancer Gene Ther advance online publication, June 6, 2008; doi:10.1038/cgt.2008.36
Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo
D-B Xiang, Z-T Chen, D Wang, M-X Li, J-Y Xie, Y-S Zhang, Y Qing, Z-P Li and J Xie
Cancer Gene Ther advance online publication, June 6, 2008; doi:10.1038/cgt.2008.30
Selective oncolytic effect of an attenuated Newcastle disease virus (NDV-HUJ) in lung tumors
B Yaacov, E Elihaoo, I lazar, M Ben-Shlomo, I Greenbaum, A Panet and Z Zakay-Rones
Cancer Gene Ther advance online publication, June 6, 2008; doi:10.1038/cgt.2008.31
Abstract | Full Text | PDF | Supplementary information
May 16 2008
A dual role of p21 waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate
S Kraljevic Pavelic, T Cacev and M Kralj
Cancer Gene Ther advance online publication, May 16, 2008; doi:10.1038/cgt.2008.28
April 18 2008
Primary neural stem/progenitor cells expressing endostatin or cytochrome P450 for gene therapy of glioblastoma
A Lorico, J Mercapide, V Soloduschko, M Alexeyev, O Fodstad and G Rappa
Cancer Gene Ther advance online publication, April 18, 2008; doi:10.1038/cgt.2008.23
A chimeric fusion of the hASH1 and EZH2 promoters mediates high and specific reporter and suicide gene expression and cytotoxicity in small cell lung cancer cells
T T Poulsen, N Pedersen, H Juel and H S Poulsen
Cancer Gene Ther advance online publication, April 18, 2008; doi:10.1038/cgt.2008.24
Vaccination of fiber-modified adenovirus-transfected dendritic cells to express HER-2/neu stimulates efficient HER-2/neu-specific humoral and CTL responses and reduces breast carcinogenesis in transgenic mice
S Sas, T Chan, A Sami, A El-Gayed and J Xiang
Cancer Gene Ther advance online publication, April 18, 2008; doi:10.1038/cgt.2008.18
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Short Communications
July 4 2008
E. coli nitroreductase/CB1954 gene-directed enzyme prodrug therapy: role of arylamine N-acetlytransferase 2
D J Mitchell and R F Minchin
Cancer Gene Ther advance online publication, July 4, 2008; doi:10.1038/cgt.2008.47