ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
November 6 2009 |
October 30 2009 |
October 23 2009 |
October 16 2009 |
October 9 2009 |
October 2 2009 |
September 18 2009 |
September 11 2009 |
September 4 2009 |
August 28 2009 |
August 7 2009 |
July 24 2009 |
July 17 2009 |
July 10 2009 |
July 3 2009 |
June 26 2009 |
June 19 2009 |
June 5 2009
November 13 2009
Original Article
Using lentiviral vectors for efficient pancreatic cancer gene therapy
E Ravet, H Lulka, F Gross, L Casteilla, L Buscail and P Cordelier
Cancer Gene Ther advance online publication, November 13, 2009; doi:10.1038/cgt.2009.79
November 6 2009
Original Articles
Human neural stem cells transduced with IFN-
and cytosine deaminase genes intensify bystander effect in experimental glioma
S Ito, A Natsume, S Shimato, M Ohno, T Kato, P Chansakul, T Wakabayashi and S U Kim
Cancer Gene Ther advance online publication, November 6, 2009; doi:10.1038/cgt.2009.80
Fusogenic membrane glycoproteins induce syncytia formation and death in vitro and in vivo: a potential therapy agent for lung cancer
E-H Lin, C Salon, E Brambilla, D Lavillette, J Szecsi, F-L Cosset and J-L Coll
Cancer Gene Ther advance online publication, November 6, 2009; doi:10.1038/cgt.2009.74
Genetic immunotherapy of lung cancer using conditionally replicating adenovirus and adenovirus-interferon-
M-Y Park, D R Kim, H W Jung, H-I Yoon, J H Lee and C-T Lee
Cancer Gene Ther advance online publication, November 6, 2009; doi:10.1038/cgt.2009.78
Bovine herpesvirus type 1 as a novel oncolytic virus
R Rodrigues, B Cuddington and K Mossman
Cancer Gene Ther advance online publication, November 6, 2009; doi:10.1038/cgt.2009.77
Identification of virus resistant tumor cell subpopulations in three-dimensional uveal melanoma cultures
K Valyi-Nagy, S Dosa, S K Kovacs, S Bacsa, A Voros, D Shukla, R Folberg and T Valyi-Nagy
Cancer Gene Ther advance online publication, November 6, 2009; doi:10.1038/cgt.2009.73
October 30 2009
Original Articles
Reduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells
J L Dembinski, E L Spaeth, J Fueyo, C Gomez-Manzano, M Studeny, M Andreeff and F C Marini
Cancer Gene Ther advance online publication, October 30, 2009; doi:10.1038/cgt.2009.67
Survivin knockdown by short hairpin RNA abrogates the growth of human hepatocellular carcinoma xenografts in nude mice
R Zhang, L Ma, M Zheng, J Ren, T Wang, Y Meng, J Zhao, L Jia, L Yao, H Han, K Li and A Yang
Cancer Gene Ther advance online publication, October 30, 2009; doi:10.1038/cgt.2009.68
October 23 2009
Original Articles
Intratumoral delivery of shRNA targeting cyclin D1 attenuates pancreatic cancer growth
S J Deharvengt, J R Gunn, S B Pickett and M Korc
Cancer Gene Ther advance online publication, October 23, 2009; doi:10.1038/cgt.2009.75
The anti-glioma effect of suicide gene therapy using BMSC expressing HSV/TK combined with overexpression of Cx43 in glioma cells
Q Huang, X-Z Liu, C-S Kang, G-X Wang, Y Zhong and P-Y Pu
Cancer Gene Ther advance online publication, October 23, 2009; doi:10.1038/cgt.2009.64
An HDAC inhibitor enhances the antitumor activity of a CMV promoter-driven DNA vaccine
M-D Lai, C-S Chen, C-R Yang, S-Y Yuan, J-J Tsai,, C-F Tu, C-C Wang, M-C Yen and C-C Lin
Cancer Gene Ther advance online publication, October 23, 2009; doi:10.1038/cgt.2009.65
October 16 2009
Original Articles
Viral vector-induced expression of bone morphogenetic protein 2 produces inhibition of tumor growth and bone differentiation of stem cells
S Fong, M-K Chan, A Fong, W J Bowers and K J Kelly
Cancer Gene Ther advance online publication, October 16, 2009; doi:10.1038/cgt.2009.56
Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter
S Prabhakar, G J Brenner, B Sung, S M Messerli, J Mao, M Sena-Esteves, A Stemmer-Rachamimov, B Tannous and X O Breakefield
Cancer Gene Ther advance online publication, October 16, 2009; doi:10.1038/cgt.2009.71
October 9 2009
Original Articles
Improved nonviral cancer suicide gene therapy using survivin promoter-driven mutant Bax
H Garg, R Salcedo, G Trinchieri and R Blumenthal
Cancer Gene Ther advance online publication, October 9, 2009; doi:10.1038/cgt.2009.63
In vitro and in vivo delivery of novel anticancer fusion protein MULT1E/FasTI via adenoviral vectors
H S R Kotturi, J Li, M Branham-O'Connor, X Yu, T E Wagner and Y Wei
Cancer Gene Ther advance online publication, October 9, 2009; doi:10.1038/cgt.2009.69
Silencing of HIF-1
suppresses tumorigenicity of renal cell carcinoma through induction of apoptosis
K Xu, Q Ding, Z Fang, J Zheng, P Gao, Y Lu and Y Zhang
Cancer Gene Ther advance online publication, October 9, 2009; doi:10.1038/cgt.2009.66
October 2 2009
Original Articles
A modified hTERT promoter-directed oncolytic adenovirus replication with concurrent inhibition of TGF signaling for breast cancer therapy
Z Hu, J S Robbins, A Pister, M B Zafar, Z-W Zhang, J Gupta, K J Lee, K Neuman, C-O Yun, T Guise and P Seth
Cancer Gene Ther advance online publication, October 2, 2009; doi:10.1038/cgt.2009.72
Antitumor activity of Ad-IU2, a prostate-specific replication-competent adenovirus encoding the apoptosis inducer, TRAIL
J A Jiménez, X Li, Y-P Zhang, K H Bae, Y Mohammadi, P Pandya, C Kao and T A Gardner
Cancer Gene Ther advance online publication, October 2, 2009; doi:10.1038/cgt.2009.62
Enhanced specific delivery and targeting of oncolytic Sindbis viral vectors by modulating vascular leakiness in tumor
J-C Tseng, T Granot, V DiGiacomo, B Levin and D Meruelo
Cancer Gene Ther advance online publication, October 2, 2009; doi:10.1038/cgt.2009.70
Inhibition of tumor growth and induction of apoptosis in prostate cancer cell lines by overexpression of tissue inhibitor of matrix metalloproteinase-3
L Zhang, L Zhao, D Zhao, G Lin, B Guo, Y Li, Z Liang, X J Zhao and X Fang
Cancer Gene Ther advance online publication, October 2, 2009; doi:10.1038/cgt.2009.59
September 18 2009
Original Article
Fusion enzymes containing HSV-1 thymidine kinase mutants and guanylate kinase enhance prodrug sensitivity in vitro and in vivo
A Ardiani, M Sanchez-Bonilla and M E Black
Cancer Gene Ther advance online publication, September 18, 2009; doi:10.1038/cgt.2009.60
September 11 2009
Original Article
Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method
L Li, L N Liu, S Feller, C Allen, R Shivakumar, J Fratantoni, L A Wolfraim, H Fujisaki, D Campana, N Chopas, S Dzekunov and M Peshwa
Cancer Gene Ther advance online publication, September 11, 2009; doi:10.1038/cgt.2009.61
September 4 2009
Original Articles
Adenovirus-mediated transfer of siRNA against survivin enhances the radiosensitivity of human non-small cell lung cancer cells
C-T Yang, J-M Li, H-H Weng, Y-C Li, H-C Chen and M-F Chen
Cancer Gene Ther advance online publication, September 4, 2009; doi:10.1038/cgt.2009.55
Inhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivo
C Yang, Y Tong, W Ni, J Liu, W Xu, L Li, X Liu, H Meng and W Qian
Cancer Gene Ther advance online publication, September 4, 2009; doi:10.1038/cgt.2009.57
August 28 2009
Original Articles
Enhancement of reporter gene detection sensitivity by insertion of specific mini-peptide-coding sequences
J Cutrera, D Dibra, X Xia and S Li
Cancer Gene Ther advance online publication, August 28, 2009; doi:10.1038/cgt.2009.54
An enteric pathogen Salmonella enterica serovar Typhimurium suppresses tumor growth by downregulating CD44high and CD4T regulatory (Treg) cell expression in mice: the critical role of lipopolysaccharide and Braun lipoprotein in modulating tumor growth
T Liu and A K Chopra
Cancer Gene Ther advance online publication, August 28, 2009; doi:10.1038/cgt.2009.58
August 7 2009
Original Article
Intraperitoneal administration of telomerase-specific oncolytic adenovirus sensitizes ovarian cancer cells to cisplatin and affects survival in a xenograft model with peritoneal dissemination CGTOpen
M Takakura, M Nakamura, S Kyo, M Hashimoto, N Mori, T Ikoma, Y Mizumoto, T Fujiwara, Y Urata and M Inoue
Cancer Gene Ther advance online publication, August 7, 2009; doi:10.1038/cgt.2009.44
July 24 2009
Original Article
Oncolytic and immunostimulatory efficacy of a targeted oncolytic poxvirus expressing human GM-CSF following intravenous administration in a rabbit tumor model CGTOpen
J-H Lee, M-S Roh, Y-K Lee, M-K Kim, J-Y Han, B-H Park, P Trown, D H Kirn and T-H Hwang
Cancer Gene Ther advance online publication, July 24, 2009; doi:10.1038/cgt.2009.50
July 17 2009
Original Articles
Heat-induced transcription of diphtheria toxin A or its variants, CRM176 and CRM197: implications for pancreatic cancer gene therapy
P Fogar, F Navaglia, D Basso, C-F Zambon, L Moserle, S Indraccolo, A Stranges, E Greco, E Fadi, A Padoan, G Pantano, M C Sanzari, S Pedrazzoli, C Montecucco and M Plebani
Cancer Gene Ther advance online publication, July 17, 2009; doi:10.1038/cgt.2009.48
Suppression of ovarian cancer growth via systemic administration with liposome-encapsulated adenovirus-encoding endostatin
L Yang, L Wang, X-q Su, L Wang, X-c Chen, D Li, S-t Luo, H-s Shi, L-j Chen and Y-s Wang
Cancer Gene Ther advance online publication, July 17, 2009; doi:10.1038/cgt.2009.47
July 10 2009
Original Article
Downregulation of the coxsackie and adenovirus receptor in cancer cells by hypoxia depends on HIF-1
K Küster, A Koschel, N Rohwer, A Fischer, B Wiedenmann and M Anders
Cancer Gene Ther advance online publication, July 10, 2009; doi:10.1038/cgt.2009.49
Letter to the Editor
Activated Ras signaling significantly enhances reovirus replication and spread
M Shmulevitz, P Marcato and P W K Lee
Cancer Gene Ther advance online publication, July 10, 2009; doi:10.1038/cgt.2009.46
July 3 2009
Original Article
Antitumoral efficacy of DNA nanoparticles in murine models of lung cancer and pulmonary metastasis
M Rodrigo-Garzón, P Berraondo, L Ochoa, J J Zulueta and G González-Aseguinolaza
Cancer Gene Ther advance online publication, July 3, 2009; doi:10.1038/cgt.2009.45
June 26 2009
Original Article
Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA
H Tanooka, K Tatsumi, H Tsuji, Y Noda, T Katsube, H Ishii, A Ootsuyama, F Takeshita and T Ochiya
Cancer Gene Ther advance online publication, June 26, 2009; doi:10.1038/cgt.2009.43
June 19 2009
Original Article
Enhancement of antitumor activity of gammaretrovirus carrying IL-12 gene through genetic modification of envelope targeting HER2 receptor: a promising strategy for bladder cancer therapy
Y-S Tsai, A-L Shiau, Y-F Chen, H-T Tsai, T-S Tzai and C-L Wu
Cancer Gene Ther advance online publication, June 19, 2009; doi:10.1038/cgt.2009.41
June 5 2009
Original Article
Oncolytic adenovirus expressing interleukin-18 induces significant antitumor effects against melanoma in mice through inhibition of angiogenesis
J-N Zheng, D-S Pei, L-J Mao, X-Y Liu, F-H Sun, B-F Zhang, Y-Q Liu, J-J Liu, W Li and D Han
Cancer Gene Ther advance online publication, June 5, 2009; doi:10.1038/cgt.2009.38
