ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
July 3 2009 |
June 26 2009 |
June 19 2009 |
June 5 2009 |
May 29 2009 |
May 22 2009 |
May 15 2009 |
May 1 2009 |
April 24 2009 |
April 17 2009 |
April 10 2009 |
March 20 2009 |
March 13 2009 |
February 27 2009 |
February 20 2009 |
February 6 2009
July 10 2009
Original Article
Downregulation of the coxsackie and adenovirus receptor in cancer cells by hypoxia depends on HIF-1
K Küster, A Koschel, N Rohwer, A Fischer, B Wiedenmann and M Anders
Cancer Gene Ther advance online publication, July 10, 2009; doi:10.1038/cgt.2009.49
Letter to the Editor
Activated Ras signaling significantly enhances reovirus replication and spread
M Shmulevitz, P Marcato and P W K Lee
Cancer Gene Ther advance online publication, July 10, 2009; doi:10.1038/cgt.2009.46
July 3 2009
Original Article
Antitumoral efficacy of DNA nanoparticles in murine models of lung cancer and pulmonary metastasis
M Rodrigo-Garzón, P Berraondo, L Ochoa, J J Zulueta and G González-Aseguinolaza
Cancer Gene Ther advance online publication, July 3, 2009; doi:10.1038/cgt.2009.45
June 26 2009
Original Article
Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA
H Tanooka, K Tatsumi, H Tsuji, Y Noda, T Katsube, H Ishii, A Ootsuyama, F Takeshita and T Ochiya
Cancer Gene Ther advance online publication, June 26, 2009; doi:10.1038/cgt.2009.43
June 19 2009
Original Article
Enhancement of antitumor activity of gammaretrovirus carrying IL-12 gene through genetic modification of envelope targeting HER2 receptor: a promising strategy for bladder cancer therapy
Y-S Tsai, A-L Shiau, Y-F Chen, H-T Tsai, T-S Tzai and C-L Wu
Cancer Gene Ther advance online publication, June 19, 2009; doi:10.1038/cgt.2009.41
June 5 2009
Original Articles
Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy
D Boczkowski, J Lee, S Pruitt and S Nair
Cancer Gene Ther advance online publication, June 5, 2009; doi:10.1038/cgt.2009.39
Dynamics of multiple myeloma tumor therapy with a recombinant measles virus
D Dingli, C Offord, R Myers, K-W Peng, T W Carr, K Josic, S J Russell and Z Bajzer
Cancer Gene Ther advance online publication, June 5, 2009; doi:10.1038/cgt.2009.40
Effect of sonoporation on cationic liposome-mediated IFN
gene therapy for metastatic hepatic tumors of murine colon cancer
S Hayashi, M Mizuno, J Yoshida and A Nakao
Cancer Gene Ther advance online publication, June 5, 2009; doi:10.1038/cgt.2008.1
Oncolytic adenovirus expressing interleukin-18 induces significant antitumor effects against melanoma in mice through inhibition of angiogenesis
J-N Zheng, D-S Pei, L-J Mao, X-Y Liu, F-H Sun, B-F Zhang, Y-Q Liu, J-J Liu, W Li and D Han
Cancer Gene Ther advance online publication, June 5, 2009; doi:10.1038/cgt.2009.38
May 29 2009
Original Article
New pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster
J F Spencer, J E Sagartz, W S M Wold and K Toth
Cancer Gene Ther advance online publication, May 29, 2009; doi:10.1038/cgt.2009.36
May 22 2009
Original Articles
Novel strategies to augment genetically delivered immunotoxin molecular therapy for cancer therapy
X Liu, J Wu, S Zhang, C Li and Q Huang
Cancer Gene Ther advance online publication, May 22, 2009; doi:10.1038/cgt.2009.30
Adenovirus delivery of human CD40 ligand gene confers direct therapeutic effects on carcinomas
L Vardouli, C Lindqvist, K Vlahou, A S I Loskog and A G Eliopoulos
Cancer Gene Ther advance online publication, May 22, 2009; doi:10.1038/cgt.2009.31
WT1 gene silencing by aerosol delivery of PEI–RNAi complexes inhibits B16-F10 lung metastases growth
D E Zamora-Avila, P Zapata-Benavides, M A Franco-Molina, S Saavedra-Alonso, L M Trejo-Avila, D Reséndez-Pérez, J L Méndez-Vázquez, J Isaias-Badillo and C Rodríguez-Padilla
Cancer Gene Ther advance online publication, May 22, 2009; doi:10.1038/cgt.2009.35
May 15 2009
Review
Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers
R R Weichselbaum and D Kufe
Cancer Gene Ther advance online publication, May 15, 2009; doi:10.1038/cgt.2009.37
Original Articles
Anticancer oncolytic activity of respiratory syncytial virus
I Echchgadda, S Kota, I DeLa Cruz, A Sabbah, T Chang, R Harnack, V Mgbemena, B Chatterjee and S Bose
Cancer Gene Ther advance online publication, May 15, 2009; doi:10.1038/cgt.2009.34
Conditional interleukin-12 gene therapy promotes safe and effective antitumor immunity
H Komita, X Zhao, A K Katakam, P Kumar, M Kawabe, H Okada, J M Braughler and W J Storkus
Cancer Gene Ther advance online publication, May 15, 2009; doi:10.1038/cgt.2009.33
Combination of human tumor necrosis factor-alpha (hTNF-) gene delivery with gemcitabine is effective in models of pancreatic cancer
S R Murugesan, C R King, R Osborn, W R Fairweather, E M O'Reilly, M O Thornton and L L Wei
Cancer Gene Ther advance online publication, May 15, 2009; doi:10.1038/cgt.2009.32
May 1 2009
Original Article
RNA interference-mediated knockdown of p21WAF1 enhances anti-tumor cell activity of oncolytic adenoviruses CGTOpen
M Shiina, M D Lacher, C Christian and W M Korn
Cancer Gene Ther advance online publication, May 1, 2009; doi:10.1038/cgt.2009.29
April 24 2009
Original Article
Adenoviral-mediated, intratumor gene transfer of interleukin 23 induces a therapeutic antitumor response
J Reay, S-H Kim, E Lockhart, J Kolls and P D Robbins
Cancer Gene Ther advance online publication, April 24, 2009; doi:10.1038/cgt.2009.27
April 17 2009
Original Article
Lentiviruses with trastuzumab bound to their envelopes can target and kill prostate cancer cells
K-x Zhang, M Moussavi, C Kim, E Chow, I S Chen, L Fazli, W Jia and P S Rennie
Cancer Gene Ther advance online publication, April 17, 2009; doi:10.1038/cgt.2009.28
April 10 2009
Original Articles
Combined inhibition of PAK7, MAP3K7 and CK2 kinases inhibits the growth of MiaPaCa2 pancreatic cancer cell xenografts
V Giroux, J L Iovanna, S Garcia and J-C Dagorn
Cancer Gene Ther advance online publication, April 10, 2009; doi:10.1038/cgt.2009.22
CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma
L N Kaliberova, V Krendelchtchikova, D K Harmon, C R Stockard, A S Petersen, J M Markert, G Y Gillespie, W E Grizzle, D J Buchsbaum and S A Kaliberov
Cancer Gene Ther advance online publication, April 10, 2009; doi:10.1038/cgt.2009.23
Paclitaxel combined with siRNA targeting HPV16 oncogenes improves cytotoxicity for cervical carcinoma
W-l Liu, N Green, L W Seymour and M Stevenson
Cancer Gene Ther advance online publication, April 10, 2009; doi:10.1038/cgt.2009.24
Cytotoxicity of adenoviruses expressing the wild-type p53 gene to esophageal carcinoma cells is linked with the CAR expression level and indirectly with the endogenous p53 status
G Ma, K Kawamura, Q Li, N Suzuki, M Liang, M Namba, H Shimada and M Tagawa
Cancer Gene Ther advance online publication, April 10, 2009; doi:10.1038/cgt.2009.21
PNAE
can significantly reduce Burkitt's lymphoma tumor burden in a SCID mice model: cells dissemination similar to the human disease
S Matis, M R Mariani, G Cutrona, M Cilli, F Piccardi, A Daga, G Damonte, E Millo, M Moroni, S Roncella, F Fedeli, L C Boffa and M Ferrarini
Cancer Gene Ther advance online publication, April 10, 2009; doi:10.1038/cgt.2009.26
Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo
E Rognoni, M Widmaier, C Haczek, K Mantwill, R Holzmüller, B Gansbacher, A Kolk, T Schuster, R M Schmid, D Saur, A Kaszubiak, H Lage and P S Holm
Cancer Gene Ther advance online publication, April 10, 2009; doi:10.1038/cgt.2009.20
Phase I and biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors
F Xu, S Li, X-L Li, Y Guo, B-Y Zou, R Xu, H Liao, H-Y Zhao, Y Zhang, Z-Z Guan and L Zhang
Cancer Gene Ther advance online publication, April 10, 2009; doi:10.1038/cgt.2009.19
March 20 2009
Original Article
MLH1 deficiency enhances tumor cell sensitivity to ganciclovir
J J O'Konek, P D Boucher, A A Iacco, T E Wilson and D S Shewach
Cancer Gene Ther advance online publication, March 20, 2009; doi:10.1038/cgt.2009.16
March 13 2009
Original Article
Phase II trial of Belagenpumatucel-L, a TGF-2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients
J Nemunaitis, M Nemunaitis, N Senzer, P Snitz, C Bedell, P Kumar, B Pappen, P B Maples, D Shawler and H Fakhrai
Cancer Gene Ther advance online publication, March 13, 2009; doi:10.1038/cgt.2009.15
February 27 2009
Original Articles
DNAzymes to mouse 1 integrin mRNA in vivo: targeting the tumor vasculature and retarding cancer growth
J Niewiarowska, I Sacewicz, M Wiktorska, T Wysocki, O Stasikowska, M Wagrowska-Danilewicz and C S Cierniewski
Cancer Gene Ther advance online publication, February 27, 2009; doi:10.1038/cgt.2009.13
Suppression of N-Ras by shRNA-expressing plasmid increases sensitivity of HepG2 cells to vincristine-induced growth inhibition
H-x Sun, H-w He, S-h Zhang, T-g Liu, K-h Ren, Q-y He and R-g Shao
Cancer Gene Ther advance online publication, February 27, 2009; doi:10.1038/cgt.2009.14
February 20 2009
Original Articles
Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters
S Bortolanza, M Bunuales, P Alzuguren, O Lamas, R Aldabe, J Prieto and R Hernandez-Alcoceba
Cancer Gene Ther advance online publication, February 20, 2009; doi:10.1038/cgt.2009.12
Bifidobacterium longum as a delivery system of TRAIL and endostatin cooperates with chemotherapeutic drugs to inhibit hypoxic tumor growth
B Hu, L Kou, C Li, L-P Zhu, Y-R Fan, Z-W Wu, J-J Wang and G-X Xu
Cancer Gene Ther advance online publication, February 20, 2009; doi:10.1038/cgt.2009.7
Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity
T Osada, X Y Yang, Z C Hartman, O Glass, B L Hodges, D Niedzwiecki, M A Morse, H K Lyerly, A Amalfitano and T M Clay
Cancer Gene Ther advance online publication, February 20, 2009; doi:10.1038/cgt.2009.17
February 6 2009
Original Articles
An acute toxicology study with INGN 007, an oncolytic adenovirus vector, in mice and permissive Syrian hamsters; comparisons with wild-type Ad5 and a replication-defective adenovirus vector
D L Lichtenstein, J F Spencer, K Doronin, D Patra, J M Meyer, E V Shashkova, M Kuppuswamy, D Dhar, M A Thomas, A E Tollefson, L A Zumstein, W S M Wold and K Toth
Cancer Gene Ther advance online publication, February 6, 2009; doi:10.1038/cgt.2009.5
Controlling brain tumor growth by intraventricular administration of an AAV vector encoding IFN-
D H Meijer, C A Maguire, S G LeRoy and M Sena-Esteves
Cancer Gene Ther advance online publication, February 6, 2009; doi:10.1038/cgt.2009.8
INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies
B Ying, K Toth, J F Spencer, J Meyer, A E Tollefson, D Patra, D Dhar, E V Shashkova, M Kuppuswamy, K Doronin, M A Thomas, L A Zumstein, W S M Wold and D L Lichtenstein
Cancer Gene Ther advance online publication, February 6, 2009; doi:10.1038/cgt.2009.6
