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DNA REPAIR
Excision repair Mismatch repair Damage sensing Excision repair Review: Friedberg, E. C. How nucleotide excision repair protects against cancer. Nature Rev. Cancer 1, 22-33 (2001) Highlights: · A molecular monkey wrench 
Mismatch repair Highlight: · A perfect mismatch · Caught short · Mismatch repair comes to an end
Damage sensing Reviews: Skorski, T. Oncogenic tyrosine kinases and the DNA damage response. Nature Rev. Cancer. 2, 351-360 (2002) D'Amours, D. & Jackson, S. P. The Mre11 complex: DNA repair meets checkpoint signalling. Nature Rev. Mol. Cell Biol. 3, 317-327 (2002) Zhou, B.-B. S. & Elledge, S. J. The DNA damage response: putting checkpoints in perspective. Nature 408, 433-439 (2000) Highlights: · A taxing question · Breaking the cycle · Damage control · From damage to death · The replication connection · Split ends and hairpins |
