webfocus on cell division

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CHROMOSOMES

Related milestones
Chromatin
Genomics
Sister-chromatid cohesion
Spindle attachment


Related milestones

· Milestone 10: Going round in circles
· Milestone 23: Making and breaking bonds between sisters


Chromatin

Highlight:
· Foreman in the histone factory


Genomics

Research paper:
Wood, V. et al. The genome sequence of Schizosaccharomyces Pombe. Nature 415, 871-880 (2002)

News and Views:
Eisen, J. A. Genome sequencing: Brouhaha over the other yeast. Nature 415, 845-848 (2002)


Sister-chromatid cohesion

Review:
Jallepalli, P. V. & Lengauer, C. Chromosome segregation and cancer: cutting through the mystery. Nature Rev. Cancer 1, 109-117 (2001)


Research papers:
Mailand, N., et al. Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation. Nature Cell Biol. 4, 318-322
(2002)

Sullivan, M., Lehane, C. & Uhlmann, F. Orchestrating anaphase and mitotic exit: separase cleavage and localization of Slk19. Nature Cell Biol. 3, 771-777
(2001)

Prieto, I. et al. Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I. Nature Cell Biol. 3, 761-766 (2001)

Rao, H., Uhlmann, F., Nasmyth, K. & Varshavsky, A. Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature 410, 955-959 (2001)

News and Views:
Amon, A. Together until separin do us part. Nature Cell Biol. 3, E12-E14 (2001)

Pellman, D. & Christman, M. F. Separase anxiety: dissolving the sister bond and more. Nature Cell Biol. 3, E207-E209 (2001)

Highlights:
· A complex link
· Sisters find a slick way to stick
· Sisters stick together
· Stuck in the middle


Spindle attachment

Highlight:
· Kinetochore fishing