ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
October 30 2009 |
October 23 2009 |
October 16 2009 |
October 9 2009 |
October 2 2009 |
September 25 2009 |
September 18 2009 |
September 11 2009 |
September 4 2009 |
August 28 2009 |
August 21 2009 |
August 14 2009 |
July 31 2009 |
July 24 2009 |
July 17 2009 |
July 10 2009 |
June 26 2009 |
June 19 2009 |
June 12 2009 |
June 5 2009 |
May 22 2009 |
April 17 2009
November 6 2009
Original Article
Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression
Z L Wu, S S Zheng, Z M Li, Y Y Qiao, M Y Aau and Q Yu
Cell Death Differ advance online publication, November 6, 2009; doi:10.1038/cdd.2009.162
Reviews
Control of granzymes by serpins
D Kaiserman and P I Bird
Cell Death Differ advance online publication, November 6, 2009; doi:10.1038/cdd.2009.169
Regulation of death receptor signaling by the ubiquitin system
I E Wertz and V M Dixit
Cell Death Differ advance online publication, November 6, 2009; doi:10.1038/cdd.2009.168
Original Papers
BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists
K C Goldsmith, B J Lestini, M Gross, L Ip, A Bhumbla, X Zhang, H Zhao, X Liu and M D Hogarty
Cell Death Differ advance online publication, November 6, 2009; doi:10.1038/cdd.2009.171
NF45 functions as an IRES trans-acting factor that is required for translation of cIAP1 during the unfolded protein response
T E Graber, S D Baird, P N Kao, M B Mathews and M Holcik
Cell Death Differ advance online publication, November 6, 2009; doi:10.1038/cdd.2009.164
Meeting Report
The 4th International p63/p73 workshop: p53's (older) sisters take centre stage
S Basu and M P Kadakia
Cell Death Differ advance online publication, November 6, 2009; doi:10.1038/cdd.2009.170
October 30 2009
Letters to the Editor
Treasure or artifact: a decade of p63 research speaks for itself
M L Mikkola, A Costanzo, I Thesleff, D R Roop and M I Koster
Cell Death Differ advance online publication, October 30, 2009; doi:10.1038/cdd.2009.157
Brdm2—an aberrant hypomorphic p63 allele
F Talos, S Wolff, U Beyer, M Dobbelstein and U M Moll
Cell Death Differ advance online publication, October 30, 2009; doi:10.1038/cdd.2009.158
Reviews
Granzymes and perforin in solid organ transplant rejection
J C Choy
Cell Death Differ advance online publication, October 30, 2009; doi:10.1038/cdd.2009.161
Cell therapy strategies and improvements for muscular dystrophy
M Quattrocelli, M Cassano, S Crippa, I Perini and M Sampaolesi
Cell Death Differ advance online publication, October 30, 2009; doi:10.1038/cdd.2009.160
Original Papers
Caspase-dependent generation of reactive oxygen species in human astrocytoma cells contributes to resistance to TRAIL-mediated apoptosis
K Choi, S-W Ryu, S Song, H Choi, S W Kang and C Choi
Cell Death Differ advance online publication, October 30, 2009; doi:10.1038/cdd.2009.154
53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope
J-L Perfettini, R Nardacci, C Séror, S Q Raza, S Sepe, H Saïdi, F Brottes, A Amendola, F Subra, F Del Nonno, L Chessa, A D'Incecco, M-L Gougeon, M Piacentini and G Kroemer
Cell Death Differ advance online publication, October 30, 2009; doi:10.1038/cdd.2009.159
October 23 2009
Original Papers
IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells
J Gao, M Senthil, B Ren, J Yan, Q Xing, J Yu, L Zhang and J H Yim
Cell Death Differ advance online publication, October 23, 2009; doi:10.1038/cdd.2009.156
Studies of the molecular mechanism of caspase-8 activation by solution NMR
N Keller, M G Grütter and O Zerbe
Cell Death Differ advance online publication, October 23, 2009; doi:10.1038/cdd.2009.155
October 16 2009
Original Article
IGF-IR-dependent expression of Survivin is required for T-antigen-mediated protection from apoptosis and proliferation of neural progenitors
E Gualco, K Urbanska, G Perez-Liz, T Sweet, F Peruzzi, K Reiss and L Del Valle
Cell Death Differ advance online publication, October 16, 2009; doi:10.1038/cdd.2009.146
Original Papers
Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2
Z X Chen and S Pervaiz
Cell Death Differ advance online publication, October 16, 2009; doi:10.1038/cdd.2009.132
Disruption of PPAR
signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy
M Jiang, S Fernandez, W G Jerome, Y He, X Yu, H Cai, B Boone, Y Yi, M A Magnuson, P Roy-Burman, R J Matusik, S B Shappell and S W Hayward
Cell Death Differ advance online publication, October 16, 2009; doi:10.1038/cdd.2009.148
The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival
R Kang, D Tang, N E Schapiro, K M Livesey, A Farkas, P Loughran, A Bierhaus, M T Lotze and H J Zeh
Cell Death Differ advance online publication, October 16, 2009; doi:10.1038/cdd.2009.149
PI3K p110
and p110
have differential effects on Akt activation and protection against oxidative stress-induced apoptosis in myoblasts
R W Matheny Jr and M L Adamo
Cell Death Differ advance online publication, October 16, 2009; doi:10.1038/cdd.2009.150
VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2
Z Zhang, K G Neiva, M W Lingen, L M Ellis and J E Nör
Cell Death Differ advance online publication, October 16, 2009; doi:10.1038/cdd.2009.152
Meeting Report
International Cell Death Society Annual Meeting 2009
R B Birge, M J Cronje, R A Lockshin and Z Zakeri
Cell Death Differ advance online publication, October 16, 2009; doi:10.1038/cdd.2009.151
October 9 2009
Original Papers
The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease
L Elia, M Quintavalle, J Zhang, R Contu, L Cossu, M V G Latronico, K L Peterson, C Indolfi, D Catalucci, J Chen, S A Courtneidge and G Condorelli
Cell Death Differ advance online publication, October 9, 2009; doi:10.1038/cdd.2009.153
Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-xL
L Lindenboim, E Blacher, C Borner and R Stein
Cell Death Differ advance online publication, October 9, 2009; doi:10.1038/cdd.2009.145
Altered thymic selection by overexpressing cellular FLICE inhibitory protein in T cells causes lupus-like syndrome in a BALB/c but not C57BL/6 strain
G Qiao, Z Li, A W Minto, J Shia, L Yang, L Bao, J Tschopp, J-X Gao, J Wang, R J Quigg and J Zhang
Cell Death Differ advance online publication, October 9, 2009; doi:10.1038/cdd.2009.143
Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis
M Wang, R Ye, E Barron, P Baumeister, C Mao, S Luo, Y Fu, B Luo, L Dubeau, D R Hinton and A S Lee
Cell Death Differ advance online publication, October 9, 2009; doi:10.1038/cdd.2009.144
Cytomegaloviruses inhibit Bak- and Bax-mediated apoptosis with two separate viral proteins
M Çam, W Handke, M Picard-Maureau and W Brune
Cell Death Differ advance online publication, October 9, 2009; doi:10.1038/cdd.2009.147
October 2 2009
Original Papers
Caspases rather than calpains mediate remodelling of the fodrin skeleton during human placental trophoblast fusion
M Gauster, M Siwetz, K Orendi, G Moser, G Desoye and B Huppertz
Cell Death Differ advance online publication, October 2, 2009; doi:10.1038/cdd.2009.133
An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosis
R C Kovi, S Paliwal, S Pande and S R Grossman
Cell Death Differ advance online publication, October 2, 2009; doi:10.1038/cdd.2009.140
Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation
I Verbrugge, C Maas, M Heijkoop, M Verheij and J Borst
Cell Death Differ advance online publication, October 2, 2009; doi:10.1038/cdd.2009.141
Coxiella burnetii modulates Beclin 1 and Bcl-2, preventing host cell apoptosis to generate a persistent bacterial infection
C L Vázquez and M I Colombo
Cell Death Differ advance online publication, October 2, 2009; doi:10.1038/cdd.2009.129
Ubiquitin B: an essential mediator of trichostatin A-induced tumor-selective killing in human cancer cells
P Wu, Y Tian, G Chen, B Wang, L Gui, L Xi, X Ma, Y Fang, T Zhu, D Wang, L Meng, G Xu, S Wang, D Ma and J Zhou
Cell Death Differ advance online publication, October 2, 2009; doi:10.1038/cdd.2009.142
September 25 2009
Original Article
p53-mediated apoptosis prevents the accumulation of progenitor B cells and B-cell tumors
T L Slatter, P Ganesan, C Holzhauer, R Mehta, C Rubio, G Williams, M Wilson, J A Royds, M A Baird and A W Braithwaite
Cell Death Differ advance online publication, September 25, 2009; doi:10.1038/cdd.2009.136
Reviews
Novel roles for GAPDH in cell death and carcinogenesis
A Colell, D R Green and J-E Ricci
Cell Death Differ advance online publication, September 25, 2009; doi:10.1038/cdd.2009.137
Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14ARF-MDM2-p53 axis
T Van Maerken, J Vandesompele, A Rihani, A De Paepe and F Speleman
Cell Death Differ advance online publication, September 25, 2009; doi:10.1038/cdd.2009.138
Original Papers
p27BBP/eIF6 acts as an anti-apoptotic factor upstream of Bcl-2 during Xenopus laevis development
N De Marco, L Iannone, R Carotenuto, S Biffo, A Vitale and C Campanella
Cell Death Differ advance online publication, September 25, 2009; doi:10.1038/cdd.2009.128
p73 is essential for vitamin D-mediated osteoblastic differentiation
R Kommagani, A Whitlatch, M K Leonard and M P Kadakia
Cell Death Differ advance online publication, September 25, 2009; doi:10.1038/cdd.2009.135
Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death
E Lafont, D Milhas, S Carpentier, V Garcia, Z-X Jin, H Umehara, T Okazaki, K Schulze-Osthoff, T Levade, H Benoist and B Ségui
Cell Death Differ advance online publication, September 25, 2009; doi:10.1038/cdd.2009.130
Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus
B M Murphy, T Engel, A Paucard, S Hatazaki, G Mouri, K Tanaka, L P Tuffy, E M Jimenez-Mateos, I Woods, M Dunleavy, H P Bonner, R Meller, R P Simon, A Strasser, J H M Prehn and D C Henshall
Cell Death Differ advance online publication, September 25, 2009; doi:10.1038/cdd.2009.134
September 18 2009
Review
Adenosine signaling and function in glial cells
D Boison, J-F Chen and B B Fredholm
Cell Death Differ advance online publication, September 18, 2009; doi:10.1038/cdd.2009.131
Original Paper
Conformational stability and activity of p73 require a second helix in the tetramerization domain
D Coutandin, F Löhr, F H Niesen, T Ikeya, T A Weber, B Schäfer, E M Zielonka, A N Bullock, A Yang, P Güntert, S Knapp, F McKeon, H D Ou and V Dötsch
Cell Death Differ advance online publication, September 18, 2009; doi:10.1038/cdd.2009.139
September 11 2009
Original Papers
Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation
H Düssmann, M Rehm, C G Concannon, S Anguissola, M Würstle, S Kacmar, P Völler, H J Huber and J H M Prehn
Cell Death Differ advance online publication, September 11, 2009; doi:10.1038/cdd.2009.123
TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival
C A Huser, M A Pringle, V J Heath, A K Bell, H Kendrick, M J Smalley, D Crighton, K M Ryan, B A Gusterson and T Stein
Cell Death Differ advance online publication, September 11, 2009; doi:10.1038/cdd.2009.126
PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum
A Saavedra, J M García-Martínez, X Xifró, A Giralt, J F Torres-Peraza, J M Canals, M Díaz-Hernández, J J Lucas, J Alberch and E Pérez-Navarro
Cell Death Differ advance online publication, September 11, 2009; doi:10.1038/cdd.2009.127
September 4 2009
Original Papers
Features of programmed cell death in intact Xenopus oocytes and early embryos revealed by near-infrared fluorescence and real-time monitoring
C E Johnson, C D Freel and S Kornbluth
Cell Death Differ advance online publication, September 4, 2009; doi:10.1038/cdd.2009.120
Caspase-3-mediated secretion of connective tissue growth factor by apoptotic endothelial cells promotes fibrosis
P Laplante, I Sirois, M-A Raymond, V Kokta, A Béliveau, A Prat, A V Pshezhetsky and M-J Hébert
Cell Death Differ advance online publication, September 4, 2009; doi:10.1038/cdd.2009.124
miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor- in human breast cancer cells
R Spizzo, M S Nicoloso, L Lupini, Y Lu, J Fogarty, S Rossi, B Zagatti, M Fabbri, A Veronese, X Liu, R Davuluri, C M Croce, G Mills, M Negrini and G A Calin
Cell Death Differ advance online publication, September 4, 2009; doi:10.1038/cdd.2009.117
Tnfaip8 is an essential gene for the regulation of glucocorticoid-mediated apoptosis of thymocytes
M J Woodward, J de Boer, S Heidorn, M Hubank, D Kioussis, O Williams and H J M Brady
Cell Death Differ advance online publication, September 4, 2009; doi:10.1038/cdd.2009.125
August 28 2009
Original Papers
Alteration of the nuclear pore complex in Ca2+-mediated cell death
D Bano, D Dinsdale, A Cabrera-Socorro, S Maida, N Lambacher, B Mccoll, E Ferrando-May, M O Hengartner and P Nicotera
Cell Death Differ advance online publication, August 28, 2009; doi:10.1038/cdd.2009.112
Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL
S Luo and D C Rubinsztein
Cell Death Differ advance online publication, August 28, 2009; doi:10.1038/cdd.2009.121
August 21 2009
Original Papers
p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC
N R Christoffersen, R Shalgi, L B Frankel, E Leucci, M Lees, M Klausen, Y Pilpel, F C Nielsen, M Oren and A H Lund
Cell Death Differ advance online publication, August 21, 2009; doi:10.1038/cdd.2009.109
Kv1.1 and Kv1.3 channels contribute to the degeneration of retinal ganglion cells after optic nerve transection in vivo
P D Koeberle, Y Wang and L C Schlichter
Cell Death Differ advance online publication, August 21, 2009; doi:10.1038/cdd.2009.113
Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells
S Romano, A D'Angelillo, R Pacelli, S Staibano, E De Luna, R Bisogni, E-L Eskelinen, M Mascolo, G Calì, C Arra and M F Romano
Cell Death Differ advance online publication, August 21, 2009; doi:10.1038/cdd.2009.115
August 14 2009
Reviews
Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2
F Bassermann and M Pagano
Cell Death Differ advance online publication, August 14, 2009; doi:10.1038/cdd.2009.104
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs
J Silke and R Brink
Cell Death Differ advance online publication, August 14, 2009; doi:10.1038/cdd.2009.114
Original Papers
CD95 engagement mediates actin-independent and -dependent apoptotic signals
B Chaigne-Delalande, W Mahfouf, S Daburon, J-F Moreau and P Legembre
Cell Death Differ advance online publication, August 14, 2009; doi:10.1038/cdd.2009.111
Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6
E Giaime, C Sunyach, C Druon, S Scarzello, G Robert, S Grosso, P Auberger, M S Goldberg, J Shen, P Heutink, J Pouysségur, G Pagès, F Checler and C Alves da Costa
Cell Death Differ advance online publication, August 14, 2009; doi:10.1038/cdd.2009.116
Hax1 lacks BH modules and is peripherally associated to heavy membranes: implications for Omi/HtrA2 and PARL activity in the regulation of mitochondrial stress and apoptosis
D V Jeyaraju, G Cisbani, O M De Brito, E V Koonin and L Pellegrini
Cell Death Differ advance online publication, August 14, 2009; doi:10.1038/cdd.2009.110
Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H
M Mihlan, S Stippa, M Józsi and P F Zipfel
Cell Death Differ advance online publication, August 14, 2009; doi:10.1038/cdd.2009.103
TRPC channel-mediated neuroprotection by PDGF involves Pyk2/ERK/CREB pathway
H Yao, F Peng, Y Fan, X Zhu, G Hu and S J Buch
Cell Death Differ advance online publication, August 14, 2009; doi:10.1038/cdd.2009.108
July 31 2009
Original Article
Granzyme F induces a novel death pathway characterized by Bid-independent cytochrome c release without caspase activation
L Shi, L Wu, S Wang and Z Fan
Cell Death Differ advance online publication, July 31, 2009; doi:10.1038/cdd.2009.101
Review
MicroRNAs as regulators of death receptors signaling
M Garofalo, G L Condorelli, C M Croce and G Condorelli
Cell Death Differ advance online publication, July 31, 2009; doi:10.1038/cdd.2009.105
Original Papers
PICK1-mediated GluR2 endocytosis contributes to cellular injury after neuronal trauma
J D Bell, E Park, J Ai and A J Baker
Cell Death Differ advance online publication, July 31, 2009; doi:10.1038/cdd.2009.106
IPS-1 is crucial for DAP3-mediated anoikis induction by caspase-8 activation
H-M Li, D Fujikura, T Harada, J Uehara, T Kawai, S Akira, J C Reed, A Iwai and T Miyazaki
Cell Death Differ advance online publication, July 31, 2009; doi:10.1038/cdd.2009.97
July 24 2009
Original Paper
The c-MYC-interacting proapoptotic tumor suppressor BIN1 is a transcriptional target for E2F1 in response to DNA damage
E K Cassimere, S Pyndiah and D Sakamuro
Cell Death Differ advance online publication, July 24, 2009; doi:10.1038/cdd.2009.98
July 17 2009
Review
MicroRNA-mediated control in the skin
R Yi and E Fuchs
Cell Death Differ advance online publication, July 17, 2009; doi:10.1038/cdd.2009.92
Original Paper
Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin
L Danielyan, R Schäfer, A Schulz, T Ladewig, A Lourhmati, M Buadze, A L Schmitt, S Verleysdonk, D Kabisch, K Koeppen, G Siegel, B Proksch, T Kluba, A Eckert, C Köhle, T Schöneberg, H Northoff, M Schwab and C H Gleiter
Cell Death Differ advance online publication, July 17, 2009; doi:10.1038/cdd.2009.95
July 10 2009
Review
XIAP as a ubiquitin ligase in cellular signaling
S Galbán and C S Duckett
Cell Death Differ advance online publication, July 10, 2009; doi:10.1038/cdd.2009.81
June 26 2009
Reviews
Therapeutic strategies within the ubiquitin proteasome system
A G Eldridge and T O'Brien
Cell Death Differ advance online publication, June 26, 2009; doi:10.1038/cdd.2009.82
Ubiquitin-independent p53 proteasomal degradation
P Tsvetkov, N Reuven and Y Shaul
Cell Death Differ advance online publication, June 26, 2009; doi:10.1038/cdd.2009.67
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions
B Yang and S Kumar
Cell Death Differ advance online publication, June 26, 2009; doi:10.1038/cdd.2009.84
June 19 2009
Review
The multiple levels of regulation by p53 ubiquitination
J T Lee and W Gu
Cell Death Differ advance online publication, June 19, 2009; doi:10.1038/cdd.2009.77
June 12 2009
Review
MicroRNAs and glioblastoma; the stem cell connection
J Godlewski, H B Newton, E A Chiocca and S E Lawler
Cell Death Differ advance online publication, June 12, 2009; doi:10.1038/cdd.2009.71
June 5 2009
Reviews
miR-15a and miR-16-1 in cancer: discovery, function and future perspectives
R I Aqeilan, G A Calin and C M Croce
Cell Death Differ advance online publication, June 5, 2009; doi:10.1038/cdd.2009.69
The role of ubiquitylation for the control of cell death in Drosophila
A Bergmann
Cell Death Differ advance online publication, June 5, 2009; doi:10.1038/cdd.2009.70
Mdm2-mediated ubiquitylation: p53 and beyond
J-C Marine and G Lozano
Cell Death Differ advance online publication, June 5, 2009; doi:10.1038/cdd.2009.68
May 22 2009
Reviews
The miR-34 family in cancer and apoptosis
H Hermeking
Cell Death Differ advance online publication, May 22, 2009; doi:10.1038/cdd.2009.56
miR-10 in development and cancer
A H Lund
Cell Death Differ advance online publication, May 22, 2009; doi:10.1038/cdd.2009.58
April 17 2009
Reviews
Assembling the building blocks: structure and function of inhibitor of apoptosis proteins
P D Mace, S Shirley and C L Day
Cell Death Differ advance online publication, April 17, 2009; doi:10.1038/cdd.2009.45
B activation and diverse biological processes
