TABLE OF CONTENTS

Volume 16, Issue 7 (July 2009)

Special Issue on Molecular mechanisms of autophagy in mammals


The growing importance of autophagy is clearly demonstrated by the exponentially increasing number of publications in this area. Although autophagy was initially classified as a form of cell death, it is now generally accepted that this is not the case.Autophagy mostly promotes cell health and survival and, only under peculiar conditions, can it result in cellular death. In the first issue of 2009, Cell Death and Differentiation published nine reviews on the topic of Autophagy in Aging, Disease and Death. These are now followed by six other papers covering more specific aspects on the complex regulation of this process and its crosstalk with apoptosis and other essential cellular functions such as energy production, vesicular traffic and cellular immunity.

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Editorials

Toward the understanding of autophagy regulation and its interplay with cell death pathways  

G M Fimia and M Piacentini

Cell Death Differ 16: 933-934; doi:10.1038/cdd.2009.47

Caspase activation pathways: some recent progress

S P Cullen and S J Martin

Cell Death Differ 16: 935-938; doi:10.1038/cdd.2009.59

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Reviews

Role of BNIP3 and NIX in cell death, autophagy, and mitophagy   FREE

J Zhang and P A Ney

Cell Death Differ 16: 939-946; advance online publication, February 20, 2009; doi:10.1038/cdd.2009.16

Bif-1/Endophilin B1: a candidate for crescent driving force in autophagy   FREE

Y Takahashi, C L Meyerkord and H-G Wang

Cell Death Differ 16: 947-955; advance online publication, March 6, 2009; doi:10.1038/cdd.2009.19

Vesicular trafficking and autophagosome formation   FREE

A Longatti and S A Tooze

Cell Death Differ 16: 956-965; advance online publication, April 17, 2009; doi:10.1038/cdd.2009.39

Life and death partners: apoptosis, autophagy and the cross-talk between them   FREE

A Eisenberg-Lerner, S Bialik, H-U Simon and A Kimchi

Cell Death Differ 16: 966-975; advance online publication, March 27, 2009; doi:10.1038/cdd.2009.33

Toll-like receptors in control of immunological autophagy   FREE

M A Delgado and V Deretic

Cell Death Differ 16: 976-983; advance online publication, May 15, 2009; doi:10.1038/cdd.2009.40

The late stages of autophagy: how does the end begin?   FREE

T Noda, N Fujita and T Yoshimori

Cell Death Differ 16: 984-990; advance online publication, May 8, 2009; doi:10.1038/cdd.2009.54

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Original Papers

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

M Uhl, O Kepp, H Jusforgues-Saklani, J-M Vicencio, G Kroemer and M L Albert

Cell Death Differ 16: 991-1005; advance online publication, February 20, 2009; doi:10.1038/cdd.2009.8

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1

J M Vicencio, C Ortiz, A Criollo, A W E Jones, O Kepp, L Galluzzi, N Joza, I Vitale, E Morselli, M Tailler, M Castedo, M C Maiuri, J Molgó, G Szabadkai, S Lavandero and G Kroemer

Cell Death Differ 16: 1006-1017; advance online publication, March 27, 2009; doi:10.1038/cdd.2009.34

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

E Laane, K Pokrovskaja Tamm, E Buentke, K Ito, P Khahariza, J Oscarsson, M Corcoran, A-C Björklund, K Hultenby, J Lundin, M Heyman, S Söderhäll, J Mazur, A Porwit, P P Pandolfi, B Zhivotovsky, T Panaretakis and D Grandér

Cell Death Differ 16: 1018-1029; advance online publication, April 24, 2009; doi:10.1038/cdd.2009.46

Different forms of cell death induced by putative BCL2 inhibitors

M Vogler, K Weber, D Dinsdale, I Schmitz, K Schulze-Osthoff, M J S Dyer and G M Cohen

Cell Death Differ 16: 1030-1039; advance online publication, April 24, 2009; doi:10.1038/cdd.2009.48

Superoxide is the major reactive oxygen species regulating autophagy

Y Chen, M B Azad and S B Gibson

Cell Death Differ 16: 1040-1052; advance online publication, May 1, 2009; doi:10.1038/cdd.2009.49

Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway

S Inoue, G Browne, G Melino and G M Cohen

Cell Death Differ 16: 1053-1061; advance online publication, March 27, 2009; doi:10.1038/cdd.2009.29

Genetic deletion of faim reveals its role in modulating c-FLIP expression during CD95-mediated apoptosis of lymphocytes and hepatocytes

J Huo, S Xu, K Guo, Q Zeng and K-P Lam

Cell Death Differ 16: 1062-1070; advance online publication, March 20, 2009; doi:10.1038/cdd.2009.26

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Corrigendum

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy FREE

E Laane, K Pokrovskaja Tamm, E Buentke, K Ito, P Kharaziha, J Oscarsson, M Corcoran, A-C Björklund, K Hultenby, J Lundin, M Heyman, S Söderhäll, J Mazur, A Porwit, P P Pandolfi, B Zhivotovsky, T Panaretakis and D Grandér

Cell Death Differ 16: 1071; doi:10.1038/cdd.2009.64

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